LC8 dynein light chain (DYNLL1) binds to the C-terminal domain of ATM-interacting protein (ATMIN/ASCIZ) and regulates its subcellular localization

2011 ◽  
Vol 414 (3) ◽  
pp. 493-498 ◽  
Author(s):  
Péter Rapali ◽  
María Flor García-Mayoral ◽  
Mónica Martínez-Moreno ◽  
Krisztián Tárnok ◽  
Katalin Schlett ◽  
...  
Keyword(s):  
Subcellular Localization ◽  
Light Chain ◽  
Dynein Light Chain ◽  
Interacting Protein ◽  
Terminal Domain

scholarly journals The Exchange Factor and Diacylglycerol Receptor RasGRP3 Interacts with Dynein Light Chain 1 through Its C-terminal Domain

2006 ◽  
Vol 281 (47) ◽  
pp. 36132-36139 ◽  
Author(s):  
Sara M. Okamura ◽  
Carolyn E. Oki-Idouchi ◽  
Patricia S. Lorenzo
Keyword(s):  
Light Chain ◽  
Dynein Light Chain ◽  
Exchange Factor ◽  
Terminal Domain

scholarly journals The astrin–kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment

2011 ◽  
Vol 192 (6) ◽  
pp. 959-968 ◽  
Author(s):  
Anja K. Dunsch ◽  
Emily Linnane ◽  
Francis A. Barr ◽  
Ulrike Gruneberg
Keyword(s):  
Light Chain ◽  
Mitotic Spindle ◽  
Metaphase Plate ◽  
Dynein Light Chain ◽  
Interacting Protein ◽  
Anaphase Onset ◽  
Chromatid Cohesion ◽  
Interaction Partners ◽  
Chromosome Alignment ◽  
Correct Alignment

Astrin is a mitotic spindle–associated protein required for the correct alignment of all chromosomes at the metaphase plate. Astrin depletion delays chromosome alignment and causes the loss of normal spindle architecture and sister chromatid cohesion before anaphase onset. Here we describe an astrin complex containing kinastrin/SKAP, a novel kinetochore and mitotic spindle protein, and three minor interaction partners: dynein light chain, Plk1, and Sgo2. Kinastrin is the major astrin-interacting protein in mitotic cells, and is required for astrin targeting to microtubule plus ends proximal to the plus tip tracking protein EB1. Cells overexpressing or depleted of kinastrin mislocalize astrin and show the same mitotic defects as astrin-depleted cells. Importantly, astrin fails to localize to and track microtubule plus ends in cells depleted of or overexpressing kinastrin. These findings suggest that microtubule plus end targeting of astrin is required for normal spindle architecture and chromosome alignment, and that perturbations of this pathway result in delayed mitosis and nonphysiological separase activation.

Cloning and Response to Gravity of The Silkworm Dynein Light Chain 8 Gene*

2009 ◽  
Vol 36 (3) ◽  
pp. 364-370
Author(s):  
Zong-Cheng TIAN ◽  
Ai-Rong QIAN ◽  
Hui-Yun XU ◽  
Sheng-Meng DI ◽  
Wei ZHANG ◽  
...  
Keyword(s):  
Light Chain ◽  
Dynein Light Chain

scholarly journals Function of the NH2-terminal domain of the regulatory light chain on the regulation of smooth muscle myosin.

1994 ◽  
Vol 269 (45) ◽  
pp. 28173-28180
Author(s):  
M Ikebe ◽  
R Ikebe ◽  
H Kamisoyama ◽  
S Reardon ◽  
J P Schwonek ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Light Chain ◽  
Regulatory Light Chain ◽  
Smooth Muscle Myosin ◽  
Terminal Domain ◽  
Muscle Myosin

scholarly journals In silico whole-genome scanning of cancer-associated nonsynonymous SNPs and molecular characterization of a dynein light chain tumour variant

Oncogene ◽  
2005 ◽  
Vol 24 (40) ◽  
pp. 6133-6142 ◽  
Author(s):  
Abdel Aouacheria ◽  
Vincent Navratil ◽  
Wenyu Wen ◽  
Ming Jiang ◽  
Dominique Mouchiroud ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Light Chain ◽  
In Silico ◽  
Nonsynonymous Snps ◽  
Whole Genome ◽  
Dynein Light Chain ◽  
Genome Scanning
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