Multiple alternative splicing of mouse Dmrt1 during gonadal differentiation

2007 ◽  
Vol 352 (3) ◽  
pp. 630-634 ◽  
Author(s):  
Heng Lu ◽  
Xiao Huang ◽  
Liao Zhang ◽  
Yiqing Guo ◽  
Hanhua Cheng ◽  
...  
2010 ◽  
Vol 2010 ◽  
pp. 1-5
Author(s):  
Lawrence M. Agius

The provision of dynamic splicing events constitutes the reflected nature of neoplasia that locally infiltrates and systemically spreads in terms of evolutionary attributes of the primary and various secondary pathways in malignant transformation. The significant diversity in molecular characterization of the given tumor lesion would adaptively conform to dynamics of splicing as enhanced or silenced exons of the premessenger RNA molecule. The proteins synthesized are in turn potential modifiers in further gene expression within such contexts as RNA:protein and RNA:DNA binding events. The recognition of pathways of incremental scope would underline the development of lesions, such as tumors, as multiple alternative splicing phenomena primarily affecting molecular physicochemical identity. It is within contexts of operative intervention and modification that the real identity of the malignant neoplastic process arises, within terms of reference of contextual splicing events. Disrupted gene expression is thus a referential pathway in the modification of splicing that may prove constitutive or alternative, in first instance, but also aberrant as the lesion progresses locally and systemically.


2008 ◽  
Vol 68 (3) ◽  
pp. 657-663 ◽  
Author(s):  
Roscoe Klinck ◽  
Anne Bramard ◽  
Lyna Inkel ◽  
Geneviève Dufresne-Martin ◽  
Julien Gervais-Bird ◽  
...  

2005 ◽  
Vol 330 (3) ◽  
pp. 950-957 ◽  
Author(s):  
Yiqing Guo ◽  
Hanhua Cheng ◽  
Xiao Huang ◽  
Shang Gao ◽  
Hongshi Yu ◽  
...  

2006 ◽  
Vol 217 (2) ◽  
pp. 119-126 ◽  
Author(s):  
Yang Zhao ◽  
Heng Lu ◽  
Hongshi Yu ◽  
Hanhua Cheng ◽  
Rongjia Zhou

Gene ◽  
2008 ◽  
Vol 425 (1-2) ◽  
pp. 56-63 ◽  
Author(s):  
Amit Anand ◽  
Minarbha Patel ◽  
Albert Lalremruata ◽  
Ajeet Pratap Singh ◽  
Raman Agrawal ◽  
...  

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