Effects of lipopolysaccharide administration and maternal deprivation on anxiety and depressive symptoms in male and female Wistar rats: Neurobehavioral and biochemical assessments

2019 ◽  
Vol 362 ◽  
pp. 46-55 ◽  
Author(s):  
Hajar Benmhammed ◽  
Samer El Hayek ◽  
Abdeljabbar Nassiri ◽  
Rim Bousalham ◽  
Abdelhalem Mesfioui ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Wistar Rats ◽  
Maternal Deprivation ◽  
Male And Female ◽  
Female Wistar Rats

scholarly journals Serum pharmacokinetics and coagulation aberration induced by sodium dehydroacetate in male and female Wistar rats

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Yumei Zhang ◽  
Donglai Ying ◽  
Hao Liu ◽  
Zengrong Yu ◽  
Lingling Han ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Male And Female ◽  
Female Wistar Rats

Fixed-consecutive-number performance in male and female Wistar rats

1990 ◽  
Vol 37 (3) ◽  
pp. 255-261 ◽  
Author(s):  
Frans van Haaren ◽  
Annemieke van Hest
Keyword(s):  
Wistar Rats ◽  
Male And Female ◽  
Female Wistar Rats ◽  
Consecutive Number

scholarly journals The Influence of Gonadectomy on Anxiolytic and Antidepressant Effects of Melatonin in Male and Female Wistar Rats: A Possible Implication of Sex Hormones

2012 ◽  
Vol 03 (02) ◽  
pp. 162-173 ◽  
Author(s):  
El Mrabet Fatima Zahra ◽  
Lagbouri Ibtissam ◽  
Mesfioui Abdelhalim ◽  
El Hessni Aboubakr ◽  
Ouichou Ali
Keyword(s):  
Sex Hormones ◽  
Wistar Rats ◽  
Male And Female ◽  
Antidepressant Effects ◽  
Female Wistar Rats

scholarly journals Effects of Maternal Deprivation on Anxiety, Depression, and Empathy in Male and Female Offspring of Wistar Rats in the Face of Novel Objects

2019 ◽  
Vol 8 ◽  
pp. 1093
Author(s):  
Solmaz Khalifeh ◽  
Fariba Khodagholi ◽  
Mehrad Moghtadaei ◽  
Ali Behvarmanesh ◽  
Afshin Kheradmand ◽  
...  
Keyword(s):  
Life Stress ◽  
Wistar Rats ◽  
Female Offspring ◽  
Maternal Deprivation ◽  
Female Rats ◽  
Control Group ◽  
Male And Female ◽  
Male And Female Rats ◽  
Novel Objects ◽  
Anxiety Depression

Background: Early life stress (ELS) models such as maternal deprivation (MD) are used to in¬vestigate behavioral changes in rodents under stressful situations. MD is a situation in which rat pups are separated from the dam; MD has different paradigms. The purpose of this research is to evaluate the effects of maternal deprivation on anxiety, depression, and empathy in adult Wistar rats. Materials and Methods: MD was applied to pups as per specifically designed protocol to compare rats of the control group with maternal deprivation rats and also the group, which faced novel objects. Each group consisted of eight rats. In this study, separation started from postnatal day (PND) 14 for various periods up to PND 60. EPM test was undertaken to measure anxiety; moreover, FST was used to indicate levels of depression. Also, changes in the empathy ratio were also demonstrated. One-way analysis of variance (ANOVA), Tukey’s post hoc analysis, and t-test were applied to analyze the results. Results: MD-treated rats showed a significant decrease in anxiety and empathy indexes compared with those in the control group (P<0.05). However, MD significantly increased depression in both male and female rats (P<0.05). Final¬ly, exposure to novel objects decreased depression but did not have any effect on anxiety and empathy levels in MD rats (P<0.05). Conclusion: ELS may lead to various states of mood and behavior in adulthood. According to the findings of this study, depression increases due to MD, though both anxiety and empathy decrease in both male and female Wistar rats. Moreover, ex¬posure to novel objects decreases depression, while anxiety and empathy do not change signifi¬cantly with exposure to novel objects. [GMJ.2019;8:e1093]

scholarly journals Classification and genetic expression of Wistar rats with high and low hepatic microsomal UDP-glucuronosyltransferase activity towards androsterone

1982 ◽  
Vol 202 (1) ◽  
pp. 171-174 ◽  
Author(s):  
Michio Matsui ◽  
Hiroshi K. Watanabe
Keyword(s):  
High Activity ◽  
Wistar Rats ◽  
Autosomal Dominant ◽  
Transferase Activity ◽  
Male And Female ◽  
Genetic Expression ◽  
Autosomal Dominant Fashion ◽  
Female Wistar Rats ◽  
Udp Glucuronosyltransferase ◽  
Low Activity

Male and female Wistar rats with high and low hepatic microsomal UDP-glucuronosyltransferase activity towards androsterone were classified by partial hepatectomy. The breeding experiments between the classified high-activity and low-activity rats show that the genetic expression of the high transferase activity is inherited in an autosomal dominant fashion.

scholarly journals Compulsive sucrose- and cocaine-seeking behaviors in male and female Wistar rats

2018 ◽  
Vol 235 (8) ◽  
pp. 2395-2405 ◽  
Author(s):  
Udita Datta ◽  
Mariangela Martini ◽  
Meiyun Fan ◽  
WenLin Sun
Keyword(s):  
Wistar Rats ◽  
Male And Female ◽  
Cocaine Seeking ◽  
Female Wistar Rats
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