A mild traumatic brain injury (mTBI) induces secondary attention-deficit hyperactivity disorder-like symptomology in young rats

2015 ◽  
Vol 286 ◽  
pp. 285-292 ◽  
Author(s):  
Richelle Mychasiuk ◽  
Harleen Hehar ◽  
Michael J. Esser
Keyword(s):  
Traumatic Brain Injury ◽  
Attention Deficit Hyperactivity Disorder ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Attention Deficit ◽  
Hyperactivity Disorder ◽  
Young Rats

scholarly journals Neuropsychological Performance of Youth with Secondary Attention-Deficit/Hyperactivity Disorder 6- and 12-Months after Traumatic Brain Injury

2014 ◽  
Vol 20 (10) ◽  
pp. 971-981 ◽  
Author(s):  
Tisha J. Ornstein ◽  
Sanya Sagar ◽  
Russell J. Schachar ◽  
Linda Ewing-Cobbs ◽  
Sandra B. Chapman ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Attention Deficit Hyperactivity Disorder ◽  
Brain Injury ◽  
Executive Control ◽  
Attention Deficit ◽  
Executive Dysfunction ◽  
Control Measures ◽  
Post Injury ◽  
Psychiatric Interview ◽  
Hyperactivity Disorder

AbstractThe present study compared executive dysfunction among children with attention-deficit/hyperactivity disorder (ADHD) after traumatic brain injury (TBI), also called secondary ADHD (S-ADHD), pre-injury ADHD and children with TBI only (i.e., no ADHD). Youth aged 6–16 years admitted for TBI to five trauma centers were enrolled (n=177) and evaluated with a semi-structured psychiatric interview scheduled on three occasions (within 2 weeks of TBI, i.e., baseline assessment for pre-injury status; 6-months and 12-months post-TBI). This permitted the determination of 6- and 12-month post-injury classifications of membership in three mutually exclusive groups (S-ADHD; pre-injury ADHD; TBI-only). Several executive control measures were administered. Unremitted S-ADHD was present in 17/141 (12%) children at the 6-month assessment, and in 14/125 (11%) children at 12-months post-injury. The study found that children with S-ADHD exhibited deficient working memory, attention, and psychomotor speed as compared to children with pre-injury ADHD. Furthermore, the children with S-ADHD and the children with TBI-only were impaired compared to the children with pre-injury ADHD with regard to planning. No group differences related to response inhibition emerged. Age, but not injury severity, gender, or adaptive functioning was related to executive function outcome. Neuropsychological sequelae distinguish among children who develop S-ADHD following TBI and those with TBI only. Moreover, there appears to be a different pattern of executive control performance in those who develop S-ADHD than in children with pre-injury ADHD suggesting that differences exist in the underlying neural mechanisms that define each disorder, underscoring the need to identify targeted treatment interventions. (JINS, 2014,20, 971–981)

Attention Deficit Hyperactivity Disorder in Children and Adolescents Following Traumatic Brain Injury

2004 ◽  
Vol 25 (1-2) ◽  
pp. 159-177 ◽  
Author(s):  
Jeffrey E. Max ◽  
Amy E. Lansing ◽  
Sharon L. Koele ◽  
Carlos S. Castillo ◽  
Hirokazu Bokura ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Attention Deficit Hyperactivity Disorder ◽  
Brain Injury ◽  
Children And Adolescents ◽  
Attention Deficit ◽  
Hyperactivity Disorder
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