The effects of Ginkgo biloba extract on cognitive functions in aged female rats: The role of oxidative stress and brain-derived neurotrophic factor

2015 ◽  
Vol 278 ◽  
pp. 453-461 ◽  
Author(s):  
Muaz Belviranlı ◽  
Nilsel Okudan
2011 ◽  
Vol 59 (5) ◽  
pp. 628-636 ◽  
Author(s):  
Patricia Rojas ◽  
Norma Serrano-García ◽  
Omar N. Medina-Campos ◽  
José Pedraza-Chaverri ◽  
Sven O. Ögren ◽  
...  

Salmand ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. 234-247
Author(s):  
Bahman Hasanvand ◽  
◽  
Alireza Farhadi ◽  

Objectives: The current study aims to examine the effect of combined exercises and ginkgo biloba supplementation for 8 weeks on Brain-Derived Neurotrophic Factor (BDNF) level in depressed older men. Methods & Materials: Forty depressed older men were randomly divided into four groups of exercise (n=10), supplementation (n=10), exercise + supplementation (n=10), and control (n=10). In the pre-test phase, blood samples were taken from the subjects. Then the participants in the exercise group performed combined exercises for eight weeks, 3 sessions per week. Those in the supplementation group, the subjects were given 80 mg of ginkgo biloba extract daily for eight weeks. In the exercise + supplementation group, the subjects received both interventions simultaneously. Blood samples were taken again 24 hours after the end of intervention. Collected data were analyzed using paired t-test, one-way ANOVA, and Bonferroni Post Hoc Test. Results: Eight weeks of combined exercise alone, ginkgo biloba supplementation alone, and combined exercise and ginkgo biloba supplementation simultaneously significantly increased BDNF level in depressed older men (P<0.05). The increase in the BDNF level of subjects in the exercise + supplementation group was higher (84.78) compared to the exercise (74.37) and supplementation (72.20) groups. Conclusion: Simultaneous use of combined exercises and ginkgo biloba supplementation can be used by geriatricians to improve brain function of depressed older men.


2013 ◽  
Vol 38 (10) ◽  
pp. 2136-2147 ◽  
Author(s):  
Smita Jain ◽  
Basu Dev Banerjee ◽  
Rafat Sultana Ahmed ◽  
Vinod Kumar Arora ◽  
Pramod Kumari Mediratta

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