To attack, or not to attack? The role of serotonin transporter genotype in the display of maternal aggression

2013 ◽  
Vol 242 ◽  
pp. 135-141 ◽  
Author(s):  
Rebecca S. Heiming ◽  
Andrea Mnning ◽  
Friederike Jansen ◽  
Vanessa Kloke ◽  
Klaus-Peter Lesch ◽  
...  
2014 ◽  
Vol 6 (3) ◽  
pp. 284-291
Author(s):  
Changjian Qiu ◽  
Liansheng Zhao ◽  
Xiang Liu ◽  
Yue Yu ◽  
Yajing Meng ◽  
...  

2013 ◽  
Vol 14 (5) ◽  
pp. 522-530 ◽  
Author(s):  
Donatella Marazziti ◽  
Paola Landi ◽  
Stefano Baroni ◽  
Federica Vanelli ◽  
Natalia Bartolommei ◽  
...  

Author(s):  
Sabrina I. Hanswijk ◽  
Daan van Rooij ◽  
Jaap Oosterlaan ◽  
Marjolein Luman ◽  
Pieter J. Hoekstra ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Xiaonan Lin ◽  
Yanmiao Cao ◽  
Linqin Ji ◽  
Wenxin Zhang

AbstractMany efforts have been devoted to investigating the effect of the interaction between the serotonin transporter gene (5-HTTLPR) and environment (G × E) on depression, but they yield mixed results. The inconsistency has suggested that G × E effects may be more complex than originally conceptualized, and further study is warranted. This study explored the association among 5-HTTLPR, peer victimization and depressive symptoms and the underlying mediating role of inhibitory control in this association. A total of 871 Chinese Han adolescents (Mage = 15.32 years, 50.3% girls) participated and provided saliva samples from which the 5-HTTLPR was genotyped. This study found that 5-HTTLPR interacted with peer victimization in predicting depressive symptoms. Adolescents carrying L allele reported more depressive symptoms than SS carriers when exposed to higher level of peer victimization. Furthermore, adolescents’ inhibitory control deficits mediated the association between 5-HTTLPR × peer victimization and depressive symptoms. These findings suggested that one pathway in which G × E may confer vulnerability to depressive symptoms is through disruptions to adolescents’ inhibitory control system.


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