Selective breeding for 50kHz ultrasonic vocalization emission produces alterations in the ontogeny and regulation of rough-and-tumble play

2012 ◽  
Vol 229 (1) ◽  
pp. 138-144 ◽  
Author(s):  
E.S. Webber ◽  
K.M. Harmon ◽  
T.J. Beckwith ◽  
S. Peña ◽  
J. Burgdorf ◽  
...  
Keyword(s):  
Selective Breeding ◽  
Ultrasonic Vocalization

Effects of selective breeding for infant rat ultrasonic vocalization on cardiac responses to isolation.

2002 ◽  
Vol 116 (4) ◽  
pp. 612-623 ◽  
Author(s):  
Susan A. Brunelli ◽  
Michael M. Myers ◽  
Shira L. Asekoff ◽  
Myron A. Hofer
Keyword(s):  
Selective Breeding ◽  
Ultrasonic Vocalization ◽  
Cardiac Responses ◽  
Infant Rat

Five generations of selective breeding for ultrasonic vocalization (USV) responses in N:NIH strain rats

1997 ◽  
Vol 31 (4) ◽  
pp. 255-265 ◽  
Author(s):  
Susan A. Brunelli ◽  
Danielle D. Vinocur ◽  
Dorene Soo-Hoo ◽  
Myron A. Hofer
Keyword(s):  
Selective Breeding ◽  
Ultrasonic Vocalization

scholarly journals Whole-Genome Sequencing and Characterization of Buffalo Genetic Resources: Recent Advances and Future Challenges

Animals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 904
Author(s):  
Saif ur Rehman ◽  
Faiz-ul Hassan ◽  
Xier Luo ◽  
Zhipeng Li ◽  
Qingyou Liu
Keyword(s):  
Selective Breeding ◽  
Reference Genome ◽  
De Novo ◽  
Phenotypic Diversity ◽  
Molecular Data ◽  
Genomic Diversity ◽  
Production Performance ◽  
Phylogeographic Structure ◽  
Economic Significance ◽  
And Performance

The buffalo was domesticated around 3000–6000 years ago and has substantial economic significance as a meat, dairy, and draught animal. The buffalo has remained underutilized in terms of the development of a well-annotated and assembled reference genome de novo. It is mandatory to explore the genetic architecture of a species to understand the biology that helps to manage its genetic variability, which is ultimately used for selective breeding and genomic selection. Morphological and molecular data have revealed that the swamp buffalo population has strong geographical genomic diversity with low gene flow but strong phenotypic consistency, while the river buffalo population has higher phenotypic diversity with a weak phylogeographic structure. The availability of recent high-quality reference genome and genotyping marker panels has invigorated many genome-based studies on evolutionary history, genetic diversity, functional elements, and performance traits. The increasing molecular knowledge syndicate with selective breeding should pave the way for genetic improvement in the climatic resilience, disease resistance, and production performance of water buffalo populations globally.

scholarly journals A humanized version of Foxp2 affects ultrasonic vocalization in adult female and male mice

2021 ◽  
Author(s):  
Sophie Merten ◽  
Christine Pfeifle ◽  
Sven Künzel ◽  
Svenja Hoier ◽  
Diethard Tautz
Keyword(s):  
Adult Female ◽  
Ultrasonic Vocalization ◽  
Male Mice

scholarly journals An FGA Frameshift Variant Associated with Afibrinogenemia in Dachshunds

Genes ◽  
2021 ◽  
Vol 12 (7) ◽  
pp. 1065
Author(s):  
Reinhard Mischke ◽  
Julia Metzger ◽  
Ottmar Distl
Keyword(s):  
Protein Sequence ◽  
Sanger Sequencing ◽  
Selective Breeding ◽  
Genome Wide Association Study ◽  
Frameshift Mutation ◽  
Homozygosity Mapping ◽  
Genomic Region ◽  
Severe Bleeding ◽  
Genome Wide ◽  
A Genome

Congenital fibrinogen disorders are very rare in dogs. Cases of afibrinogenemia have been reported in Bernese Mountain, Bichon Frise, Cocker Spaniel, Collie, Lhasa Apso, Viszla, and St. Bernard dogs. In the present study, we examined four miniature wire-haired Dachshunds with afibrinogenemia and ascertained their pedigree. Homozygosity mapping and a genome-wide association study identified a candidate genomic region at 50,188,932–64,187,680 bp on CFA15 harboring FGB (fibrinogen beta chain), FGA (fibrinogen alpha chain), and FGG (fibrinogen gamma-B chain). Sanger sequencing of all three fibrinogen genes in two cases and validation of the FGA-associated mutation (FGA:g.6296delT, NC_006597.3:g.52240694delA, rs1152388481) in pedigree members showed a perfect co-segregation with afibrinogenemia-affected phenotypes, obligate carriers, and healthy animals. In addition, the rs1152388481 variant was validated in 393 Dachshunds and samples from 33 other dog breeds. The rs1152388481 variant is predicted to modify the protein sequence of both FGA transcripts (FGA201:p.Ile486Met and FGA-202:p.Ile555Met) leading to proteins truncated by 306 amino acids. The present data provide evidence for a novel FGA truncating frameshift mutation that is very likely to explain the cases of severe bleeding due to afibrinogenemia in a Dachshund family. This mutation has already been spread in Dachshunds through carriers before cases were ascertained. Genetic testing allows selective breeding to prevent afibrinogenemia-affected puppies in the future.

Sign in / Sign up

Export Citation Format

Share Document