scholarly journals Acute cognitive impairment after lateral fluid percussion brain injury recovers by 1 month: Evaluation by conditioned fear response

2007 ◽  
Vol 177 (2) ◽  
pp. 347-357 ◽  
Author(s):  
J LIFSHITZ ◽  
B WITGEN ◽  
M GRADY
Keyword(s):  
Cognitive Impairment ◽  
Brain Injury ◽  
Conditioned Fear ◽  
Fear Response ◽  
Conditioned Fear Response ◽  
Fluid Percussion ◽  
Lateral Fluid Percussion

scholarly journals A Mouse Model for Juvenile, Lateral Fluid Percussion Brain Injury Reveals Sex-Dependent Differences in Neuroinflammation and Functional Recovery

2020 ◽  
Vol 37 (4) ◽  
pp. 635-646 ◽  
Author(s):  
Elizabeth A. Newell ◽  
Brittany P. Todd ◽  
Zili Luo ◽  
Lucy P. Evans ◽  
Polly J. Ferguson ◽  
...  
Keyword(s):  
Brain Injury ◽  
Mouse Model ◽  
Functional Recovery ◽  
Fluid Percussion ◽  
Lateral Fluid Percussion

scholarly journals Regional Induction of c-Fos and Heat Shock Protein-72 mRNA following Fluid-Percussion Brain Injury in the Rat

1995 ◽  
Vol 15 (3) ◽  
pp. 467-473 ◽  
Author(s):  
Ramesh Raghupathi ◽  
Frank A. Welsh ◽  
Daniel H. Lowenstein ◽  
Thomas A. Gennarelli ◽  
Tracy K. McIntosh
Keyword(s):  
Brain Injury ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Cellular Response ◽  
Granule Cells ◽  
Subcortical White Matter ◽  
Specific Expression ◽  
Fluid Percussion ◽  
Lateral Fluid Percussion ◽  
The Impact

To evaluate the cellular response to traumatic brain injury, the expression of mRNA for c- fos and the 72-kDa heat shock protein (hsp72) was determined using in situ hybridization following lateral fluid-percussion injury (2.2–2.4 atm) in rat brain. At 2 h after injury, induction of c- fos mRNA was observed throughout the cortex ipsilateral to the site of injury, while increased expression of hsp72 mRNA was restricted to regions of the cortex surrounding the contusion area. An increase in c- fos mRNA, but not hsp72 mRNA, was observed bilaterally in the CA3 subfield of the hippocampus and the granule cells of the dentate gyrus and in the thalamus ipsilateral to the impact site. By 6 h, increased expression of c- fos mRNA was observed only in the corpus callosum on the impact side; hsp72 mRNA persisted in the deep cortical layers and upper layers of the subcortical white matter below the site of maximal injury. By 24 h, both c- fos and hsp72 mRNA had returned to control levels in all regions of the brain. These results demonstrate that lateral fluid– percussion brain injury triggers regionally and temporally specific expression of c- fos and hsp72 mRNA, which may be suggestive of differential neurochemical alterations in neurons and glia following experimental brain injury.

Response of the Contralateral Hippocampus to Lateral Fluid Percussion Brain Injury

2006 ◽  
Vol 23 (9) ◽  
pp. 1330-1342 ◽  
Author(s):  
Lorriann D. Tran ◽  
Jonathan Lifshitz ◽  
Brent M. Witgen ◽  
Elizabeth Schwarzbach ◽  
Akiva S. Cohen ◽  
...  
Keyword(s):  
Brain Injury ◽  
Fluid Percussion ◽  
Lateral Fluid Percussion
Sign in / Sign up

Export Citation Format

Share Document