Zaprinast consolidates long-term memory when administered to neonate chicks trained using a weakly reinforced single trial passive avoidance task

2006 ◽  
Vol 169 (1) ◽  
pp. 181-185 ◽  
Author(s):  
Emma Campbell ◽  
Thomas Edwards
Keyword(s):  
Passive Avoidance ◽  
Passive Avoidance Task ◽  
Long Term Memory ◽  
Avoidance Task ◽  
Single Trial ◽  
Term Memory

Vasopressin/oxytocin-related peptides influence long-term memory of a passive avoidance task in the cuttlefish, Sepia officinalis

2010 ◽  
Vol 93 (2) ◽  
pp. 240-247 ◽  
Author(s):  
Isabelle Bardou ◽  
Jérôme Leprince ◽  
Raymond Chichery ◽  
Hubert Vaudry ◽  
Véronique Agin
Keyword(s):  
Passive Avoidance ◽  
Passive Avoidance Task ◽  
Long Term Memory ◽  
Avoidance Task ◽  
Sepia Officinalis ◽  
Term Memory

scholarly journals Sotalol does not interfere with the antielectroshock action of selected second-generation antiepileptic drugs in mice

2021 ◽  
Author(s):  
Kinga K. Borowicz-Reutt ◽  
Monika Banach ◽  
Monika Rudkowska ◽  
Anna Stachniuk
Keyword(s):  
Antiepileptic Drugs ◽  
Second Generation ◽  
Antidepressant Drug ◽  
Experimental Models ◽  
Long Term Memory ◽  
Avoidance Task ◽  
Maximal Electroshock ◽  
Term Memory ◽  
The Brain

Abstract Background Due to blocking β-receptors, and potassium KCNH2 channels, sotalol may influence seizure phenomena. In the previous study, we have shown that sotalol potentiated the antielectroshock action of phenytoin and valproate in mice. Materials and methods As a continuation of previous experiments, we examined the effect of sotalol on the action of four chosen second-generation antiepileptic drugs (oxcarbazepine, lamotrigine, pregabalin, and topiramate) against the maximal electroshock in mice. Undesired effects were evaluated in the chimney test (motor impairment) and step-through passive-avoidance task (long-term memory deficits). Finally, brain concentrations of antiepileptics were determined by fluorescence polarization immunoassay, while those of sotalol by liquid chromatography–mass spectrometry. Results Sotalol at doses of up to 100 mg/kg did not affect the electroconvulsive threshold. Applied at doses of 80–100 mg/kg, sotalol did not affect the antielectroshock action of oxcarbazepine, lamotrigine, pregabalin, or topiramate. Sotalol alone and in combinations with antiepileptics impaired neither motor performance nor long-term memory. Finally, sotalol significantly decreased the brain concentrations of lamotrigine and increased those of oxcarbazepine and topiramate. Pharmacokinetic interactions, however, did not influence the final antielectroshock effects of above-mentioned drug combinations. On the other hand, the brain concentrations of sotalol were not changed by second-generation antiepileptics used in this study. Conclusion Sotalol did not reduce the antielectroshock action of four second-generation antiepileptic drugs examined in this study. Therefore, this antidepressant drug should not interfere with antiseizure effects of lamotrigine, oxcarbazepine, pregabalin, and topiramate in patients with epilepsy. To draw final conclusions, our preclinical data should still be confirmed in other experimental models and clinical conditions.

Evaluation of potential antiamnesic activities of aqueous extract of Vitex trifolia leaves against scopolamine induced amnesia and in normal rats

2015 ◽  
Vol 26 (2) ◽  
Author(s):  
Amberkar Vittal Rao Mohanbabu ◽  
Meena Kumari Kamal Kishore ◽  
Bangalore Revanna Chandrashekar ◽  
Hoskeri Dakappa Pradeepa ◽  
Rockson Christopher ◽  
...  
Keyword(s):  
Working Memory ◽  
Passive Avoidance ◽  
Probe Trial ◽  
Water Maze ◽  
Long Term Memory ◽  
Localization Task ◽  
Traditional Use ◽  
Term Memory ◽  
Memory Enhancing

AbstractThe goal of this study was to evaluate the cerebroprotective and cognition-enhancing activities of the aqueousReference or working memory and long-term memory in rodents were tested by experimental paradigms like passive avoidance (PA) and T-maze (TM), respectively. TM and Morris water maze (MWM) were used to screen putative spatial or localization task and the navigation memory-enhancing activities ofThe higher dose (20 mg/kg) of plant extract exhibited significant (p<0.01) antiamnesic activity in the PA and TM models vs. the control. In the MWM test, at probe trial,These results partly substantiate the traditional use of

scholarly journals A CREB2-targeting microRNA is required for long-term memory after single-trial learning

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Sergei A. Korneev ◽  
Dimitris V. Vavoulis ◽  
Souvik Naskar ◽  
Varvara E. Dyakonova ◽  
Ildikó Kemenes ◽  
...  
Keyword(s):  
Long Term Memory ◽  
Single Trial ◽  
Term Memory

Dextrorphan blocks long- but not short-term memory in a passive avoidance task in rats

1991 ◽  
Vol 205 (1) ◽  
pp. 109-111 ◽  
Author(s):  
Jolanta Sierocinska ◽  
Eugeniusz Nikolaev ◽  
Wojciech Danysz ◽  
Leszek Kaczmarek
Keyword(s):  
Passive Avoidance ◽  
Short Term Memory ◽  
Passive Avoidance Task ◽  
Avoidance Task ◽  
Short Term ◽  
Term Memory
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