scholarly journals Alteration of the Intestinal Microbiota by Broad-Spectrum Antibiotic Use Correlates with the Occurrence of Intestinal Graft-versus-Host Disease

2019 ◽  
Vol 25 (10) ◽  
pp. 1933-1943 ◽  
Author(s):  
Sung-Eun Lee ◽  
Ji-Young Lim ◽  
Da-Bin Ryu ◽  
Tae Woo Kim ◽  
Sung Soo Park ◽  
...  
Keyword(s):  
Intestinal Microbiota ◽  
Graft Versus Host Disease ◽  
Broad Spectrum ◽  
Antibiotic Use ◽  
Broad Spectrum Antibiotic ◽  
Host Disease ◽  
Graft Versus Host

scholarly journals Murine Syngeneic Graft-Versus-Host Disease Is Responsive to Broad-Spectrum Antibiotic Therapy

2011 ◽  
Vol 186 (6) ◽  
pp. 3726-3734 ◽  
Author(s):  
J. Anthony Brandon ◽  
C. Darrell Jennings ◽  
Alan M. Kaplan ◽  
J. Scott Bryson
Keyword(s):  
Antibiotic Therapy ◽  
Graft Versus Host Disease ◽  
Broad Spectrum ◽  
Broad Spectrum Antibiotic ◽  
Host Disease ◽  
Graft Versus Host

scholarly journals The Role of Intestinal Microbiota in Acute Graft-versus-Host Disease

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Yuanyuan Chen ◽  
Ye Zhao ◽  
Qiao Cheng ◽  
Depei Wu ◽  
Haiyan Liu
Keyword(s):  
Immune Responses ◽  
Intestinal Microbiota ◽  
Graft Versus Host Disease ◽  
Inflammatory Diseases ◽  
Hematopoietic Stem ◽  
Host Disease ◽  
Graft Versus Host ◽  
Host Immune Responses ◽  
Acute Graft

The mammalian intestinal microbiota is a complex ecosystem that plays an important role in host immune responses. Recent studies have demonstrated that alterations in intestinal microbiota composition are linked to multiple inflammatory diseases in humans, including acute graft-versus-host disease (aGVHD). aGVHD is one of the major obstacles in allogeneic hematopoietic stem cell transplantation (allo-HSCT), characterized by tissue damage in the gastrointestinal (GI) tract, liver, lung, and skin. Here, we review the current understanding of the role of intestinal microbiota in the control of immune responses during aGVHD. Additionally, the possibility of using probiotic strains for potential treatment or prevention of aGVHD will be discussed.

scholarly journals Intestinal microbiota-related effects on graft-versus-host disease

2015 ◽  
Vol 101 (5) ◽  
pp. 428-437 ◽  
Author(s):  
Yusuke Shono ◽  
Melissa D. Docampo ◽  
Jonathan U. Peled ◽  
Suelen M. Perobelli ◽  
Robert R. Jenq
Keyword(s):  
Intestinal Microbiota ◽  
Graft Versus Host Disease ◽  
Host Disease ◽  
Graft Versus Host

Early Use of Etanercept for Graft-Versus-Host Disease After Liver Transplant: the Importance of Broad Spectrum Infective Prophylaxis

2020 ◽  
Vol 18 (1) ◽  
pp. 123-127 ◽  
Author(s):  
Annalisa Boscolo ◽  
Eugenia Menin ◽  
Beatrice Zelaschi ◽  
Laura Albertoni ◽  
Giacomo Zanus ◽  
...  
Keyword(s):  
Liver Transplant ◽  
Graft Versus Host Disease ◽  
Broad Spectrum ◽  
Host Disease ◽  
Graft Versus Host ◽  
Early Use

Preventive usage of broad spectrum chemokine inhibitor NR58-3.14.3 reduces the severity of pulmonary and hepatic graft-versus-host disease

2009 ◽  
Vol 89 (3) ◽  
pp. 383-397 ◽  
Author(s):  
Sandra Miklos ◽  
Gunnar Mueller ◽  
Yayi Chang ◽  
Abdellatif Bouazzaoui ◽  
Elena Spacenko ◽  
...  
Keyword(s):  
Graft Versus Host Disease ◽  
Broad Spectrum ◽  
Host Disease ◽  
Graft Versus Host
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