scholarly journals American Society for Blood and Marrow Transplantation Pharmacy Special Interest Group Survey on Chimeric Antigen Receptor T Cell Therapy Administrative, Logistic, and Toxicity Management Practices in the United States

2019 ◽  
Vol 25 (1) ◽  
pp. 26-33 ◽  
Author(s):  
Zahra Mahmoudjafari ◽  
Kelly G. Hawks ◽  
Angela A. Hsieh ◽  
Dragos Plesca ◽  
Katie S. Gatwood ◽  
...  
2020 ◽  
Vol 55 (9) ◽  
pp. 1706-1715 ◽  
Author(s):  
Salvatore Fiorenza ◽  
David S. Ritchie ◽  
Scott D. Ramsey ◽  
Cameron J. Turtle ◽  
Joshua A. Roth

2018 ◽  
Vol 144 (8) ◽  
pp. 2043-2050 ◽  
Author(s):  
Lijuan Gou ◽  
Jianchao Gao ◽  
Huan Yang ◽  
Chenyan Gao

2019 ◽  
Vol 22 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Karen Freijer ◽  
Sheri Volger ◽  
János G. Pitter ◽  
Elizabeth Molsen-David ◽  
Clarissa Cooblall ◽  
...  

Immunotherapy ◽  
2020 ◽  
Vol 12 (18) ◽  
pp. 1341-1357
Author(s):  
Nashwa El-Khazragy ◽  
Sherief Ghozy ◽  
Passant Emad ◽  
Mariam Mourad ◽  
Diaaeldeen Razza ◽  
...  

Taking advantage of the cellular immune system is the mainstay of the adoptive cell therapy, to induce recognition and destruction of cancer cells. The impressive demonstration of this principle is chimeric antigen receptor-modified T (CAR-T)-cell therapy, which had a major impact on treating relapsed and refractory hematological malignancies. Despite the great results of the CAR-T-cell therapy, many tumors are still able to avoid immune detection and further elimination, as well as the possible associated adverse events. Herein, we highlighted the recent advances in CAR-T-cell therapy, discussing their applications beneficial functions and side effects in hematological malignancies, illustrating the underlying challenges and opportunities. Furthermore, we provide an overview to overcome different obstacles using potential manufacture and treatment strategies.


Sign in / Sign up

Export Citation Format

Share Document