scholarly journals Single Ultra-High-Dose Cholecalciferol to Prevent Vitamin D Deficiency in Pediatric Hematopoietic Stem Cell Transplantation

2018 ◽  
Vol 24 (9) ◽  
pp. 1856-1860 ◽  
Author(s):  
Gregory Wallace ◽  
Sonata Jodele ◽  
Kasiani C. Myers ◽  
Christopher E. Dandoy ◽  
Javier El-Bietar ◽  
...  
2014 ◽  
Vol 36 (2) ◽  
pp. 126-131 ◽  
Author(s):  
Denise Johnsson Campos ◽  
Gleyne Lopes Kujew Biagini ◽  
Vaneuza Araujo Moreira Funke ◽  
Carmem Maria Sales Bonfim ◽  
César Luiz Boguszewski ◽  
...  

Blood ◽  
2013 ◽  
Vol 122 (21) ◽  
pp. 5499-5499
Author(s):  
Andrea Z Pereira ◽  
Juliana Bernardo Silva ◽  
Silvia MF Pivocari ◽  
Marcia Tanaka ◽  
Fabiana Lucio ◽  
...  

Abstract Introduction There are few studies on the behavior of vitamin D in patients undergoing Hematopoietic Stem Cell Transplantation (HSCT), although vitamin D serum levels are associated with use of corticosteroids and immunosuppressive drugs. In some studies, vitamin D deficiency in patients after HSCT is associated with reduced bone density, increased of parathyroid hormone and GVHD. Objectives To study vitamin D deficiency in patients undergoing to HSCT. Methods 51 patients who underwent HSCT at Albert Einstein Hospital, São Paulo, Brazil, were studied (28 male, 23 female) with a mean age of 50 ± 16 years, in the period from 2012 to 2013. Results 54 % had serum levels of vitamin D ≤ 50 nmol/l. And, 12% had serum levels of vitamin D ≤ 25 nmol/l. A multivariate analysis showed that more age and higher Body Mass Index (BMI) were significantly associated to lower serum levels of vitamin D. A negative correlation was found between BMI and serum level of vitamin D (rp=0,37). Conclusion The use of corticosteroids, immunosuppressive drugs and less lack of sun exposure during the HSCT and during the first year post-HSCT are associated with a greater tendency to deficiency of vitamin D. This deficiency can cause muscle and bone diseases, which can be prevented with diagnosis and early treatment. The deficiency of vitamin D should be carefully investigated in the elderly and obese patients. Disclosures: No relevant conflicts of interest to declare.


2015 ◽  
Vol 21 (2) ◽  
pp. S107 ◽  
Author(s):  
Gregory Wallace ◽  
Sonata Jodele ◽  
Kasiani C. Myers ◽  
Ashley Teusink ◽  
Catherine Holtzapfel ◽  
...  

2017 ◽  
Vol 65 (2) ◽  
pp. e26817 ◽  
Author(s):  
Kristen Beebe ◽  
Kyrie Magee ◽  
Annmarie McNulty ◽  
Jennifer Stahlecker ◽  
Dana Salzberg ◽  
...  

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