A Phase I Trial of Mesenchymal Stem Cells Transfected with a Plasmid Secreting Interferon Beta in Advanced Ovarian Cancer

Amanda Olson; Frank Marini; Shannon Westin; Robert Coleman; Peter Thall; Vivian Al Jhadhami; Muzaffar H. Qazilbash; Katy Rezvani; Melissa Timmons; Lauren Heese; Rui-Yu Wang; Richard E. Champlin; Elizabeth J. Shpall; Michael Andreeff

doi:10.1016/j.bbmt.2017.12.556

A Phase I Trial of Mesenchymal Stem Cells Transfected with a Plasmid Secreting Interferon Beta in Advanced Ovarian Cancer

Biology of Blood and Marrow Transplantation ◽

10.1016/j.bbmt.2017.12.556 ◽

2018 ◽

Vol 24 (3) ◽

pp. S473

Author(s):

Amanda Olson ◽

Frank Marini ◽

Shannon Westin ◽

Robert Coleman ◽

Peter Thall ◽

...

Keyword(s):

Ovarian Cancer ◽

Stem Cells ◽

Mesenchymal Stem Cells ◽

Phase I ◽

Phase I Trial ◽

Interferon Beta ◽

Advanced Ovarian Cancer

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A phase I trial of mesenchymal stem cells transfected with a plasmid secreting interferon beta in advanced ovarian cancer

Cytotherapy ◽

10.1016/j.jcyt.2018.02.017 ◽

2018 ◽

Vol 20 (5) ◽

pp. S11-S12

Author(s):

A. Olson ◽

F. Marini ◽

S. Westin ◽

R. Coleman ◽

P. Thall ◽

...

Keyword(s):

Ovarian Cancer ◽

Stem Cells ◽

Mesenchymal Stem Cells ◽

Phase I ◽

Phase I Trial ◽

Interferon Beta ◽

Advanced Ovarian Cancer

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Abstract 75: A phase I trial of mesenchymal stem cells transfected with a plasmid secreting interferon beta in advanced ovarian cancer

10.1158/1538-7445.am2018-75 ◽

2018 ◽

Author(s):

Michael Andreeff ◽

Frank C. Marini ◽

Shannon N. Westin ◽

Robert L. Coleman ◽

Peter F. Thall ◽

...

Keyword(s):

Ovarian Cancer ◽

Stem Cells ◽

Mesenchymal Stem Cells ◽

Phase I ◽

Phase I Trial ◽

Interferon Beta ◽

Advanced Ovarian Cancer

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What factors influence advanced ovarian cancer patient (AOC pt) outcomes to phase I trial treatments?

Journal of Clinical Oncology ◽

10.1200/jco.2014.32.15_suppl.5560 ◽

2014 ◽

Vol 32 (15_suppl) ◽

pp. 5560-5560

Author(s):

Timothy Anthony Yap ◽

Angela George ◽

Caroline O Michie ◽

Mabel Wong ◽

Rebecca Bowen ◽

...

Keyword(s):

Ovarian Cancer ◽

Cancer Patient ◽

Phase I ◽

Phase I Trial ◽

Ovarian Cancer Patient ◽

Advanced Ovarian Cancer

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Cisplatin, Paclitaxel and Escalating Doses of Doxorubicin (TAP) in Advanced Ovarian Cancer: a Phase I Trial

Japanese Journal of Clinical Oncology ◽

10.1093/jjco/hyh098 ◽

2004 ◽

Vol 34 (9) ◽

pp. 540-546 ◽

Cited By ~ 4

Author(s):

T. Onda

Keyword(s):

Ovarian Cancer ◽

Phase I ◽

Phase I Trial ◽

Advanced Ovarian Cancer

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Two-Year Follow-Up Outcomes of Premature Infants Enrolled in the Phase I Trial of Mesenchymal Stem Cells Transplantation for Bronchopulmonary Dysplasia

The Journal of Pediatrics ◽

10.1016/j.jpeds.2017.02.061 ◽

2017 ◽

Vol 185 ◽

pp. 49-54.e2 ◽

Cited By ~ 62

Author(s):

So Yoon Ahn ◽

Yun Sil Chang ◽

Ji Hye Kim ◽

Se In Sung ◽

Won Soon Park

Keyword(s):

Stem Cells ◽

Mesenchymal Stem Cells ◽

Phase I ◽

Bronchopulmonary Dysplasia ◽

Premature Infants ◽

Phase I Trial ◽

Stem Cells Transplantation

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Phase I trial of carboplatin-cyclophosphamide and iproplatin-cyclophosphamide in advanced ovarian cancer: a Southwest Oncology Group study

Cancer Treatment Reviews ◽

10.1016/0305-7372(85)90023-4 ◽

1985 ◽

Vol 12 ◽

pp. 83-92 ◽

Cited By ~ 9

Author(s):

David Alberts ◽

Nancy Mason ◽

Earl Surwit ◽

Sheldon Weiner ◽

Neel Hammond ◽

...

Keyword(s):

Ovarian Cancer ◽

Phase I ◽

Phase I Trial ◽

Advanced Ovarian Cancer ◽

Oncology Group ◽

Oncology Group Study ◽

Southwest Oncology Group ◽

Southwest Oncology Group Study

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302. Phase I Trial of Intraperitoneal (IP) Administration of an Oncolytic Measles Virus (MV) Derivative, Expressing the Human Carcinoembryonic Antigen (CEA) in Patients with Advanced Ovarian Cancer (OvCa)

Molecular Therapy ◽

10.1016/s1525-0016(16)39705-2 ◽

2008 ◽

Vol 16 ◽

pp. S113

Keyword(s):

Ovarian Cancer ◽

Phase I ◽

Carcinoembryonic Antigen ◽

Measles Virus ◽

Phase I Trial ◽

Advanced Ovarian Cancer

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A combination of a fixed dose of carboplatin plus paclitaxel and adriamycin in first line therapy for advanced ovarian cancer and suboptimal surgical cytoreduction. A phase I trial of the Spanish group for ovarian cancer research and treatment (GEICO)

European Journal of Cancer ◽

10.1016/s0959-8049(99)81361-6 ◽

1999 ◽

Vol 35 ◽

pp. S239 ◽

Cited By ~ 2

Author(s):

A. Cervantes ◽

A. Poveda ◽

A. González ◽

B. Massuti ◽

C. Balañá ◽

...

Keyword(s):

Ovarian Cancer ◽

Cancer Research ◽

Phase I ◽

Phase I Trial ◽

Advanced Ovarian Cancer ◽

Fixed Dose ◽

First Line ◽

First Line Therapy ◽

Line Therapy

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Optimizing patient derived mesenchymal stem cells as virus carriers for a Phase I clinical trial in ovarian cancer

Journal of Translational Medicine ◽

10.1186/1479-5876-11-20 ◽

2013 ◽

Vol 11 (1) ◽

pp. 20 ◽

Cited By ~ 73

Author(s):

Emily K Mader ◽

Greg Butler ◽

Sean C Dowdy ◽

Andrea Mariani ◽

Keith L Knutson ◽

...

Keyword(s):

Ovarian Cancer ◽

Clinical Trial ◽

Stem Cells ◽

Mesenchymal Stem Cells ◽

Phase I ◽

Phase I Clinical Trial

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A phase I trial of a DNA plasmid-based vaccine targeting insulin-like growth factor binding protein-2 (IGFBP-2) in patients with advanced ovarian cancer: Preliminary safety and immunogenicity

Gynecologic Oncology ◽

10.1016/j.ygyno.2014.03.094 ◽

2014 ◽

Vol 133 ◽

pp. 30

Author(s):

J.B. Liao ◽

D.L. Cecil ◽

J. Reichow ◽

S. Parker ◽

D. Higgins ◽

...

Keyword(s):

Ovarian Cancer ◽

Growth Factor ◽

Phase I ◽

Phase I Trial ◽

Binding Protein ◽

Advanced Ovarian Cancer ◽

Insulin Like Growth Factor ◽

Factor Binding ◽

Dna Plasmid

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