scholarly journals Impact of Peritoneal Drain Placement on Respiratory and Renal Outcomes in Pediatric Patients with Veno-Occlusive Disease Following Hematopoietic Cell Transplantation

2018 ◽  
Vol 24 (3) ◽  
pp. S290
Author(s):  
Hemalatha G. Rangarajan ◽  
Vinita B. Pai ◽  
Jeffrey C. Naples ◽  
Cassandra Rush ◽  
Misti Drope ◽  
...  
Keyword(s):  
Cell Transplantation ◽  
Pediatric Patients ◽  
Hematopoietic Cell Transplantation ◽  
Occlusive Disease ◽  
Hematopoietic Cell ◽  
Renal Outcomes ◽  
Drain Placement

Early Identification of Barriers and Facilitators to Self-Management Behaviors in Pediatric Patients With Sickle Cell Disease to Minimize Hematopoietic Cell Transplantation Complications

2018 ◽  
Vol 35 (3) ◽  
pp. 199-209 ◽  
Author(s):  
Ginny L. Schulz ◽  
Rebecca H. Foster ◽  
Valerie Kennedy Lang ◽  
Alison Towerman ◽  
Shalini Shenoy ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Cell Transplantation ◽  
Sickle Cell ◽  
Pediatric Patients ◽  
Hematopoietic Cell Transplantation ◽  
Hematopoietic Cell ◽  
Barriers And Facilitators ◽  
Self Management ◽  
Cell Disease ◽  
Management Behaviors

Hematopoietic cell transplantation (HCT) is an elective, curative treatment option for patients with sickle cell disease (SCD). Transplant requires extensive self-management behaviors to be successful. The purpose of this study was to describe potential barriers and facilitators to self-management in a group of pediatric patients with SCD prior to HCT and their medical outcomes post-HCT. A multiple case study approach was used to describe 4 pairs of transplant recipients grouped by age, donor type, and donor source. Each pair included a case with minimal and increased post-HCT complications. Complications included readmissions, graft-versus-host disease, systemic infections, and survival in the first year post-HCT. Variables were retrospectively collected and content analyzed to identify barriers and facilitators within and across pairs using existing self-management frameworks. While higher risk transplants experienced more complications, 3 of the 4 cases with increased complications had a larger number of modifiable barriers identified compared with those experiencing minimal complications. At least one modifiable barrier and multiple facilitators were identified in all cases. A standardized psychosocial assessment process with an established plan to mitigate barriers and promote facilitators to self-management is essential to optimize outcomes in patients with SCD undergoing elective HCT.

scholarly journals A phase I dose finding study of intravenous voriconazole in pediatric patients undergoing hematopoietic cell transplantation

2019 ◽  
Vol 55 (5) ◽  
pp. 955-964 ◽  
Author(s):  
Jessica Knight-Perry ◽  
Cathryn Jennissen ◽  
Susie E. Long ◽  
Stefanie Hage ◽  
Todd E. DeFor ◽  
...  
Keyword(s):  
Phase I ◽  
Cell Transplantation ◽  
Pediatric Patients ◽  
Hematopoietic Cell Transplantation ◽  
Hematopoietic Cell ◽  
Dose Finding ◽  
Finding Study ◽  
Dose Finding Study
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