scholarly journals Health-Related Quality of Life Among Older Adult Related Hematopoietic Stem Cells (HSC) Donors (>60 yrs.) Is Equivalent to or Better Than That of Younger Adult Related Donors (18-60 yrs.)

2015 ◽  
Vol 21 (2) ◽  
pp. S47-S48
Author(s):  
Galen E. Switzer ◽  
Jessica G. Bruce ◽  
Deidre M. Kiefer ◽  
Hati Kobusingye ◽  
Rebecca J. Drexler ◽  
...  
Hematology ◽  
2010 ◽  
Vol 2010 (1) ◽  
pp. 248-254 ◽  
Author(s):  
Margaret Bevans

Abstract It is common knowledge that an allogeneic hematopoietic stem cell transplantation (HSCT) will have an enormous impact on the lives of transplant recipients and their families. Once an appropriate donor is identified, the curative potential of this treatment often drives the decision to proceed knowing that there will be intense physiologic toxicities and adverse effects on health-related quality of life (HRQL). Twenty-five years ago, HRQL was identified as an efficacy parameter in the evaluation of new anticancer drug therapy. Overall, the evidence suggests that an allogeneic HSCT has a significant impact on the overall HRQL of recipients, which is a result of decrements across all dimensions, including a significant symptom profile. The degree of impact on overall HRQL and the multiple dimensions varies across the transplant trajectory. Specific HRQL dimensions, such as physical function and symptoms, are easily incorporated into a clinician's assessment whereas other dimensions (eg, psychosocial) are less commonly integrated. The translation of HRQL results to improve clinical practice is not well established. Clinicians are often uncertain when to assess the scope of HRQL and how to interpret the information in a clinically meaningful way. The purpose of this review is to highlight the quality-of-life effects of allogeneic HSCT and discuss application into clinical practice.


Cancer ◽  
2014 ◽  
Vol 121 (5) ◽  
pp. 758-765 ◽  
Author(s):  
Erin E. Kent ◽  
Anita Ambs ◽  
Sandra A. Mitchell ◽  
Steven B. Clauser ◽  
Ashley Wilder Smith ◽  
...  

Healthcare ◽  
2022 ◽  
Vol 10 (1) ◽  
pp. 100
Author(s):  
Carmen Galán-Arroyo ◽  
Damián Pereira-Payo ◽  
Miguel A. Hernández-Mocholí ◽  
Eugenio Merellano-Navarro ◽  
Jorge Pérez-Gómez ◽  
...  

Introduction. Depressive disorders are mental disorders that last over time, and seriously affect the lives of the people who suffer from them, diminishing their quality of life, reducing their motor capacity, and incapacitating them in their daily lives. It is a major problem worldwide. Objective. To study the association between agility, health-related quality of life (hrqol), anthropometric status, and depression status in older adult women with depression. Design. Data collected from 685 physically active older women with depression were analyzed. Result. A moderate inverse correlation (r = −0.34) is shown between Time Up & Go (TUG) and EuroQol Five-Dimensional Three-Level Version (EQ-5D-3L). Between TUG and Geriatric Depression Scale (GDS), there is a small direct correlation (r = 0.14) between them. Between TUG and anthropometric data, all observed correlations are significant. Conclusions. There is a significant association between agility, health-related quality of life, depression, and anthropometric data in physically active older women with depression.


2015 ◽  
Vol 21 (2) ◽  
pp. 350-356 ◽  
Author(s):  
Annelies Billen ◽  
J. Alejandro Madrigal ◽  
Andre Strydom ◽  
Richard M. Szydlo ◽  
Galen E. Switzer ◽  
...  

2015 ◽  
Vol 19 (9) ◽  
pp. 2345-2349 ◽  
Author(s):  
J. E. Tinoco-Araujo ◽  
E. S. L. Orti-Raduan ◽  
D. Santos ◽  
V. A. R. Colturato ◽  
M. P. Souza ◽  
...  

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