scholarly journals A Prospective Study of Iron Overload Management in Allogeneic Hematopoietic Cell Transplantation Survivors

2010 ◽  
Vol 16 (6) ◽  
pp. 832-837 ◽  
Author(s):  
Navneet S. Majhail ◽  
Hillard M. Lazarus ◽  
Linda J. Burns
Keyword(s):  
Iron Overload ◽  
Prospective Study ◽  
Cell Transplantation ◽  
Hematopoietic Cell Transplantation ◽  
Hematopoietic Cell ◽  
Allogeneic Hematopoietic Cell Transplantation ◽  
Overload Management ◽  
A Prospective Study

Prognostic Value and Clinical Implication of Serum Ferritin Levels following Allogeneic Hematopoietic Cell Transplantation

2014 ◽  
Vol 133 (3) ◽  
pp. 310-316 ◽  
Author(s):  
Mika Nakamae ◽  
Hirohisa Nakamae ◽  
Shiro Koh ◽  
Hideo Koh ◽  
Mitsutaka Nishimoto ◽  
...  
Keyword(s):  
Cell Transplantation ◽  
Serum Ferritin ◽  
Hematopoietic Cell Transplantation ◽  
Ferritin Level ◽  
Hematopoietic Cell ◽  
Allogeneic Hematopoietic Cell Transplantation ◽  
Red Blood Cell Transfusion ◽  
Acute Phase Reactants ◽  
A Prospective Study ◽  
Worse Prognosis

Little research has been done on changes in serum ferritin (s-ferritin) levels and clinical implications following allogeneic hematopoietic cell transplantation (HCT). We retrospectively evaluated the correlation of s-ferritin levels after HCT with survival in 203 patients. The s-ferritin level was significantly elevated, with 75% of the patients showing peak levels 90 days after HCT. The level was >10,000 ng/ml in a total of 43% of the patients, a finding that was associated with febrile neutropenia or infection. The s-ferritin level at day 30 and at 1 year after HCT was significantly associated with prognosis. However, this statistically significant relationship was lost after adjusting for acute-phase reactants. We conclude that hyperferritinemia is very common and the degree of influence of a red blood cell transfusion will vary depending on the phase after HCT. A prospective study is needed to determine if iron load in and of itself contributes to a worse prognosis after HCT. © 2014 S. Karger AG, Basel

scholarly journals Iron overload adversely affects outcome of allogeneic hematopoietic cell transplantation

2008 ◽  
Vol 42 (12) ◽  
pp. 799-805 ◽  
Author(s):  
V Pullarkat ◽  
S Blanchard ◽  
B Tegtmeier ◽  
A Dagis ◽  
K Patane ◽  
...  
Keyword(s):  
Iron Overload ◽  
Cell Transplantation ◽  
Hematopoietic Cell Transplantation ◽  
Hematopoietic Cell ◽  
Allogeneic Hematopoietic Cell Transplantation

scholarly journals Iron Overload in Allogeneic Hematopoietic Cell Transplantation Outcome: A Meta-Analysis

2014 ◽  
Vol 20 (8) ◽  
pp. 1248-1251 ◽  
Author(s):  
Philippe Armand ◽  
Haesook T. Kim ◽  
Johanna M. Virtanen ◽  
Riitta K. Parkkola ◽  
Maija A. Itälä-Remes ◽  
...  
Keyword(s):  
Iron Overload ◽  
Cell Transplantation ◽  
Hematopoietic Cell Transplantation ◽  
Meta Analysis ◽  
Hematopoietic Cell ◽  
Allogeneic Hematopoietic Cell Transplantation
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