scholarly journals A Retrospective Analysis Of Risk Factors That Influence Intravenous Busulfan Kinetics In Adult Patients

2009 ◽  
Vol 15 (2) ◽  
pp. 155
Author(s):  
A. McBride ◽  
K. Fancher ◽  
J. Perkins ◽  
M. Milone ◽  
L. Shaw ◽  
...  
Keyword(s):  
Risk Factors ◽  
Retrospective Analysis ◽  
Adult Patients

scholarly journals Risk factors of ifosfamide-related encephalopathy in adult patients with cancer: A retrospective analysis

2016 ◽  
Vol 115 (9) ◽  
pp. 744-751 ◽  
Author(s):  
Yin Lo ◽  
Li-Jiuan Shen ◽  
Wen-Hwei Chen ◽  
Yaa-Hui Dong ◽  
Fe-Lin Lin Wu
Keyword(s):  
Risk Factors ◽  
Retrospective Analysis ◽  
Adult Patients ◽  
Patients With Cancer

scholarly journals Incidence of early intra-cranial bleeding and ischaemia in adult veno-arterial extracorporeal membrane oxygenation and extracorporeal cardiopulmonary resuscitation patients: a retrospective analysis of risk factors

Perfusion ◽  
2020 ◽  
Vol 35 (1_suppl) ◽  
pp. 8-17
Author(s):  
Maximilian Valentin Malfertheiner ◽  
Andrea Koch ◽  
Christoph Fisser ◽  
Jonathan Edward Millar ◽  
Lars Sigfried Maier ◽  
...  
Keyword(s):  
Risk Factors ◽  
Computed Tomography ◽  
Extracorporeal Membrane Oxygenation ◽  
Hospital Mortality ◽  
Retrospective Analysis ◽  
Adult Patients ◽  
Membrane Oxygenation ◽  
Cerebral Complications ◽  
Lower Blood ◽  
Cerebral Computed Tomography

Background: Cerebral complications in veno-arterial extracorporeal membrane oxygenation are known to have a strong impact on mortality and morbidity. Aim of this study is to investigate the early incidence, risk factors and in-hospital mortality of intra-cranial ischaemia and haemorrhage in adults undergoing veno-arterial extracorporeal membrane oxygenation treatment. Methods: This study is a single-centre retrospective analysis on adult patients undergoing veno-arterial extracorporeal membrane oxygenation for different indications. The inclusion criterion included patients with early routine cerebral computed tomography imaging during extracorporeal membrane oxygenation, with no clinical evidence of cerebral pathology prior to cannulation. Cerebral complications were grouped by aetiology and the territories of the brain’s supplying arteries. Results: One hundred eighty-seven adult patients with a total of 190 veno-arterial extracorporeal membrane oxygenation treatments were included. A total of 16.3% (n = 31) had evidence of either cerebral ischaemia (11.1%) or haemorrhage (5.8%); one patient suffered from both. Cerebral computed tomography scans were performed early in median on the first day after extracorporeal membrane oxygenation cannulation; in-hospital mortality of intra-cranial ischaemia and haemorrhage was 71.4% and 45.5%, respectively. Associated with an increased risk for ischaemic lesions were cannulation of the ascending aorta, higher age, presence of an autoimmune disease and cardiac surgery prior to veno-arterial extracorporeal membrane oxygenation. An association with haemorrhagic lesions was found for a lower blood PaCO2 at 2 hours, lower blood flow through the extracorporeal membrane oxygenation device at 2 hours, higher international normalized ratio and constantly higher activated partial thromboplastin time values as well as higher mean arterial pressures until haemorrhagic lesions were evident. Conclusion: Cerebral complications are frequent in patients on veno-arterial extracorporeal membrane oxygenation and may be clinically silent events. Careful monitoring with routine neuroimaging seems to be the most appropriate diagnostic approach at present. Intra-cranial ischaemia occurs more frequent than haemorrhage and is associated with cannulation of the aorta ascendens.

scholarly journals Incidence of and risk factors for postoperative delirium in older adult patients undergoing noncardiac surgery: a prospective study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Arissara Iamaroon ◽  
Titima Wongviriyawong ◽  
Patumporn Sura-arunsumrit ◽  
Nattikan Wiwatnodom ◽  
Nichakarn Rewuri ◽  
...  
Keyword(s):  
Risk Factors ◽  
Prospective Study ◽  
Older Adult ◽  
Postoperative Delirium ◽  
Noncardiac Surgery ◽  
Adult Patients ◽  
A Prospective Study
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