scholarly journals Long-term outcome of allogeneic stem cell transplant: Single institution experience of a large cohort

2006 ◽  
Vol 12 (2) ◽  
pp. 108-109
Author(s):  
Y.R. Abou Mourad ◽  
B.C.Y. Lau ◽  
M.J. Barnett ◽  
D.L. Forrest ◽  
D.E. Hogge ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplant ◽  
Large Cohort ◽  
Cell Transplant ◽  
Allogeneic Stem Cell Transplant ◽  
Single Institution ◽  
Term Outcome ◽  
Long Term Outcome

100 Long Term Outcome of Renal Failure in Multiple Myeloma Following Autologous Stem Cell Transplant

2011 ◽  
Vol 57 (4) ◽  
pp. B41 ◽  
Author(s):  
Siobhan V. Glavey ◽  
Morie A. Gertz ◽  
Angela Dispenzieri ◽  
Shaji Kumar ◽  
Francis Buadi ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Renal Failure ◽  
Stem Cell ◽  
Stem Cell Transplant ◽  
Autologous Stem Cell Transplant ◽  
Cell Transplant ◽  
Term Outcome ◽  
Long Term Outcome

Long-term Outcome of a Successful Cord Blood Stem Cell Transplant in Mevalonate Kinase Deficiency

PEDIATRICS ◽  
2014 ◽  
Vol 135 (1) ◽  
pp. e211-e215 ◽  
Author(s):  
Stefano Giardino ◽  
Edoardo Lanino ◽  
Giuseppe Morreale ◽  
Annalisa Madeo ◽  
Maja Di Rocco ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cord Blood ◽  
Stem Cell Transplant ◽  
Mevalonate Kinase Deficiency ◽  
Cell Transplant ◽  
Mevalonate Kinase ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Cord Blood Stem Cell

A validated symptomatic BKV risk assessment score in patient post allogeneic stem cell transplant.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e18536-e18536
Author(s):  
Ala Abudayyeh ◽  
Heather Y. Lin ◽  
Maen Abdelrahim ◽  
Gabriela Rondon ◽  
Borje Andersson ◽  
...  
Keyword(s):  
Stem Cell ◽  
High Risk ◽  
Cumulative Incidence ◽  
Stem Cell Transplant ◽  
Conditioning Regimen ◽  
Large Cohort ◽  
Grading System ◽  
Cell Transplant ◽  
Allogeneic Stem Cell Transplant ◽  
Cell Immunity

e18536 Background: BKV, Polyomavirus hominis 1, is a member of the family Polyomaviridae, is a non-enveloped virion; in the 1980s, it emerged as an important pathogen in SCT recipients. In the absence of sufficient T-cell immunity, BKV reactivation can progress, leading to prolonged hospital stays and increased mortality secondary to late hemorrhagic cystitis, ureteral stenosis, and nephropathy. In our recently completed retrospective study of 2477 SCT patients, 38.1% had developed renal impairment, and BKV viruria was present in 25%. In addition, BKV was found to be an independent predictor of chronic kidney disease and shorter survival. Using the large cohort (2477) patients studied earlier (2004-2012) we have derived a grading system to identify patients with risk of symptomatic BKV. We hypothesize that the current grading system will identify the patients at risk of symptomatic BKV at day 30 post allogeneic stem cell transplant. Methods: We performed a retrospective chart review of all patients who underwent allogeneic SCT from 2012-2016. The data was extracted from the secured database at MD Anderson cancer Center. Using the three variables that were significant predictor for symptomatic BKV derived from our initial study (conditioning regimen, HLA donor status, & underlying cancer diagnosis) we performed the analysis. Predicted cumulative incidence rate of BK infection at 30 days after transplant in 1308 patients were calculated in the presence of death as a competing risk using the “BASELINE” statement in PHREG procedure in SAS. Patients were classified into low, moderate and high risk according to the distribution of the predicted cumulative incidence of BK infection 30 days after transplant. Results: We have shown that the grading system derived from allogeneic SCT population predicted accurately the high, moderate & low risk population for developing symptomatic BKV. Conclusions: We have created and validated a grading system for symptomatic BKV in a large cohort of (1308 patients) to predict risk at day 30 post allogeneic SCT. Using this grading system we would hope to identify high risk patients for BKV and intervene early with novel therapies prior to complications associated.

scholarly journals Reduced-Intensity Allogeneic Stem Cell Transplant for Sickle Cell Disease in Pediatrics: A Single Institution Experience

2018 ◽  
Vol 24 (3) ◽  
pp. S434-S435
Author(s):  
Michael J. Eckrich ◽  
Lisa Madden ◽  
Candace Taylor ◽  
Christina Matheny ◽  
Erica Frausto-Garcia ◽  
...  
Keyword(s):  
Stem Cell ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Stem Cell Transplant ◽  
Cell Transplant ◽  
Allogeneic Stem Cell Transplant ◽  
Cell Disease ◽  
Single Institution ◽  
Reduced Intensity
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