scholarly journals Comparison of unrelated cord blood and unrelated bone marrow transplants for adults with leukemia a collaborative study: The New York blood center national cord blood program and The International bone marrow transplant registry

2004 ◽  
Vol 10 (10) ◽  
pp. 734-735 ◽  
Author(s):  
M.J. Laughlin
Keyword(s):  
New York ◽  
Bone Marrow ◽  
Cord Blood ◽  
Bone Marrow Transplant ◽  
Collaborative Study ◽  
Marrow Transplant ◽  
Bone Marrow Transplants ◽  
Blood Center ◽  
Transplant Registry ◽  
Unrelated Cord Blood

scholarly journals Should HLA-identical sibling bone marrow transplants for leukemia be restricted to large centers? [see comments]

Blood ◽  
1992 ◽  
Vol 79 (10) ◽  
pp. 2771-2774 ◽  
Author(s):  
MM Horowitz ◽  
D Przepiorka ◽  
RE Champlin ◽  
RP Gale ◽  
A Gratwohl ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplant ◽  
Chronic Phase ◽  
Marrow Transplant ◽  
Myelogenous Leukemia ◽  
Bone Marrow Transplants ◽  
Relative Risks ◽  
Disease Characteristics ◽  
First Remission ◽  
Transplant Registry

Abstract There is substantial evidence that the volume of medical procedures in a hospital has an inverse relationship with mortality. We analyzed data for 1313 recipients of HLA-identical sibling bone marrow transplants for early leukemia (acute leukemia in first remission or chronic myelogenous leukemia in first chronic phase) to determine whether transplant outcome differed in small and large centers. Transplants were performed in 86 bone marrow transplant centers active between the years 1983 and 1988, which participated in the International Bone Marrow Transplant Registry. Twenty-one (24%) centers performed five or fewer allogeneic transplants per year during the study period; five (6%) performed more than 40 per year. After adjustment for differences in patient and disease characteristics, the relative risks of treatment- related mortality (1.53, P less than .01) and treatment failure (1.38, P less than .04) were higher among patients who received transplants at centers doing five or fewer transplants per year than among those at larger centers. Among patients receiving transplants in centers performing more than five transplants a year, there was no statistically significant correlation between number of transplants and outcome.

scholarly journals Should HLA-identical sibling bone marrow transplants for leukemia be restricted to large centers? [see comments]

Blood ◽  
1992 ◽  
Vol 79 (10) ◽  
pp. 2771-2774 ◽  
Author(s):  
MM Horowitz ◽  
D Przepiorka ◽  
RE Champlin ◽  
RP Gale ◽  
A Gratwohl ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplant ◽  
Chronic Phase ◽  
Marrow Transplant ◽  
Myelogenous Leukemia ◽  
Bone Marrow Transplants ◽  
Relative Risks ◽  
Disease Characteristics ◽  
First Remission ◽  
Transplant Registry

There is substantial evidence that the volume of medical procedures in a hospital has an inverse relationship with mortality. We analyzed data for 1313 recipients of HLA-identical sibling bone marrow transplants for early leukemia (acute leukemia in first remission or chronic myelogenous leukemia in first chronic phase) to determine whether transplant outcome differed in small and large centers. Transplants were performed in 86 bone marrow transplant centers active between the years 1983 and 1988, which participated in the International Bone Marrow Transplant Registry. Twenty-one (24%) centers performed five or fewer allogeneic transplants per year during the study period; five (6%) performed more than 40 per year. After adjustment for differences in patient and disease characteristics, the relative risks of treatment- related mortality (1.53, P less than .01) and treatment failure (1.38, P less than .04) were higher among patients who received transplants at centers doing five or fewer transplants per year than among those at larger centers. Among patients receiving transplants in centers performing more than five transplants a year, there was no statistically significant correlation between number of transplants and outcome.

The International Bone Marrow Transplant Registry

2002 ◽  
Vol 76 (S1) ◽  
pp. 393-397 ◽  
Author(s):  
John M. Goldman ◽  
Mary M. Horowitz
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplant ◽  
Marrow Transplant ◽  
Transplant Registry

scholarly journals A PHASE 1 Perspective: Multivirus-Specific T CELLS from BOTH Cord Blood and BONE Marrow Transplant Donors

2016 ◽  
Vol 22 (3) ◽  
pp. S140-S141
Author(s):  
Patrick J. Hanley ◽  
Michael Daniel Keller ◽  
Maria Martin Manso ◽  
Caridad Martinez ◽  
Kathryn Leung ◽  
...  
Keyword(s):  
Bone Marrow ◽  
T Cells ◽  
Cord Blood ◽  
Bone Marrow Transplant ◽  
Phase 1 ◽  
Marrow Transplant
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