The noradrenaline re-uptake inhibitor desipramine limits pro-inflammatory cytokine production in rat cortex in vivo

2006 ◽  
Vol 20 (3) ◽  
pp. 53 ◽  
Author(s):  
Joan B. O’Sullivan ◽  
Thomas J. Connor
Keyword(s):  
Inflammatory Cytokine ◽  
Cytokine Production ◽  
Inflammatory Cytokine Production ◽  
Uptake Inhibitor ◽  
Rat Cortex

In vivo and in vitro effects of fluoroquinolones on lipopolysaccharide-induced pro-inflammatory cytokine production

2009 ◽  
Vol 15 (3) ◽  
pp. 168-173 ◽  
Author(s):  
Hiromi Ogino ◽  
Miho Fujii ◽  
Mariko Ono ◽  
Kayoko Maezawa ◽  
Junko Kizu ◽  
...  
Keyword(s):  
Inflammatory Cytokine ◽  
Cytokine Production ◽  
Inflammatory Cytokine Production ◽  
In Vitro Effects

scholarly journals Urban Aerosols Induce Pro-inflammatory Cytokine Production in Macrophages and Cause Airway Inflammation in Vivo

2010 ◽  
Vol 33 (5) ◽  
pp. 780-783 ◽  
Author(s):  
Tokuyuki Yoshida ◽  
Yasuo Yoshioka ◽  
Maho Fujimura ◽  
Hiroyuki Kayamuro ◽  
Kohei Yamashita ◽  
...  
Keyword(s):  
Airway Inflammation ◽  
Inflammatory Cytokine ◽  
Cytokine Production ◽  
Inflammatory Cytokine Production ◽  
Urban Aerosols

scholarly journals Glutathione Peroxidase-1 Primes Pro-Inflammatory Cytokine Production after LPS Challenge In Vivo

PLoS ONE ◽  
2012 ◽  
Vol 7 (3) ◽  
pp. e33172 ◽  
Author(s):  
Steven Bozinovski ◽  
Huei Jiunn Seow ◽  
Peter J. Crack ◽  
Gary P. Anderson ◽  
Ross Vlahos
Keyword(s):  
Glutathione Peroxidase ◽  
Inflammatory Cytokine ◽  
Cytokine Production ◽  
Inflammatory Cytokine Production ◽  
Glutathione Peroxidase 1 ◽  
Lps Challenge

Differential effects of lactobacilli on activation and maturation of mouse dendritic cells

2014 ◽  
Vol 5 (3) ◽  
pp. 323-334 ◽  
Author(s):  
I. Elawadli ◽  
J.T. Brisbin ◽  
B.A. Mallard ◽  
M.W. Griffiths ◽  
M. Corredig ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Immune Responses ◽  
Inflammatory Cytokine ◽  
Cytokine Production ◽  
Lactobacillus Helveticus ◽  
Inflammatory Cytokine Production

Lactic acid bacteria (LAB) are of interest because of their potential to modulate immune responses. The effects of LAB range from regulation to stimulation of the immune system. A series of studies were performed in vitro to study the effects of six lactic acid bacteria (LAB), Lactobacillus helveticus LH-2, Lactobacillus acidophilus La-5, La-115, La-116 and La-14, and Lactobacillus salivarius, on maturation and activation of mouse dendritic cells. Production of tumour necrosis factor (TNF)-?, interleukin (IL)-6 and IL-10 by dendritic cells (DCs) was determined after treating cells with live LAB. The expression of DC maturation markers, CD80 and CD40, was also measured using flow cytometry after stimulation with LAB. In addition, the expression of Toll-like receptors (TLRs) 2, 4 and 9 by DCs stimulated with LAB was measured. Our results revealed that LAB act differentially on pro-inflammatory and anti-inflammatory cytokine production and induction of co-stimulatory molecules by DCs. Specifically, L. salivarius was found to be the most effective LAB to induce pro-inflammatory cytokine production and expression of co-stimulatory molecules. Moreover, La-14, La-116 and La-5 induced moderate maturation and activation of DCs. On the other hand, LH-2 and La-115 were the least effective lactobacilli to induce DC responses. The present study also revealed that L. salivarius was able to induce the expression of TLR2, 4 and 9 by DCs. In conclusion, various strains and species of LAB can differentially regulate DC activation and maturation, providing further evidence that these bacteria may have the ability to influence and steer immune responses in vivo.

scholarly journals A Novel Compound C12 Inhibits Inflammatory Cytokine Production and Protects from Inflammatory Injury In Vivo

PLoS ONE ◽  
2011 ◽  
Vol 6 (9) ◽  
pp. e24377 ◽  
Author(s):  
Yi Wang ◽  
Congcong Yu ◽  
Yong Pan ◽  
Jianling Li ◽  
Yali Zhang ◽  
...  
Keyword(s):  
Inflammatory Cytokine ◽  
Cytokine Production ◽  
Inflammatory Cytokine Production ◽  
Inflammatory Injury
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