‘Something in the way she moves’: The functional significance of flexibility in the multiple roles of protein disulfide isomerase (PDI)

Robert B. Freedman; Jasmine L. Desmond; Lee J. Byrne; Jack W. Heal; Mark J. Howard; Narinder Sanghera; Kelly L. Walker; A. Katrine Wallis; Stephen A. Wells; Richard A. Williamson; Rudolf A. Römer

doi:10.1016/j.bbapap.2017.08.014

‘Something in the way she moves’: The functional significance of flexibility in the multiple roles of protein disulfide isomerase (PDI)

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics ◽

10.1016/j.bbapap.2017.08.014 ◽

2017 ◽

Vol 1865 (11) ◽

pp. 1383-1394 ◽

Cited By ~ 20

Author(s):

Robert B. Freedman ◽

Jasmine L. Desmond ◽

Lee J. Byrne ◽

Jack W. Heal ◽

Mark J. Howard ◽

...

Keyword(s):

Functional Significance ◽

Protein Disulfide Isomerase ◽

Multiple Roles ◽

Disulfide Isomerase ◽

Protein Disulfide ◽

The Way

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Protein disulfide isomerase: Multiple roles in the modification of nascent secretory proteins

Cell ◽

10.1016/0092-8674(89)90043-3 ◽

1989 ◽

Vol 57 (7) ◽

pp. 1069-1072 ◽

Cited By ~ 327

Author(s):

Robert B. Freedman

Keyword(s):

Protein Disulfide Isomerase ◽

Multiple Roles ◽

Secretory Proteins ◽

Disulfide Isomerase ◽

Protein Disulfide

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Promoter of the gene for the multifunctional protein disulfide isomerase polypeptide. Functional significance of the six CCAAT boxes and other promoter elements.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)49940-7 ◽

1992 ◽

Vol 267 (16) ◽

pp. 11513-11519

Author(s):

K Tasanen ◽

J Oikarinen ◽

K.I. Kivirikko ◽

T Pihlajaniemi

Keyword(s):

Functional Significance ◽

Protein Disulfide Isomerase ◽

Promoter Elements ◽

Multifunctional Protein ◽

Disulfide Isomerase ◽

Protein Disulfide

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Activation of the Renin-Angiotensin II-Aldosterone-System leads to increases in extracellular protein disulfide isomerase: role in insulin resistance

Endocrine Abstracts ◽

10.1530/endoabs.49.oc6.5 ◽

2017 ◽

Author(s):

Ricardo Perez-Fuentes ◽

Patricia Pulido ◽

Joshua Cazares ◽

Yaritza Inostroza-Nieves ◽

Enrique Torres-Rasgado ◽

...

Keyword(s):

Insulin Resistance ◽

Angiotensin Ii ◽

Protein Disulfide Isomerase ◽

Extracellular Protein ◽

Disulfide Isomerase ◽

Renin Angiotensin ◽

Protein Disulfide

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Faculty Opinions recommendation of Is protein disulfide isomerase a redox-dependent molecular chaperone?

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1007498.177269 ◽

2002 ◽

Author(s):

Karin Romisch

Keyword(s):

Molecular Chaperone ◽

Protein Disulfide Isomerase ◽

Disulfide Isomerase ◽

Protein Disulfide

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Faculty Opinions recommendation of Protein disulfide isomerase acts as a redox-dependent chaperone to unfold cholera toxin.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1010976.175608 ◽

2003 ◽

Author(s):

Bernhard Dobberstein

Keyword(s):

Cholera Toxin ◽

Protein Disulfide Isomerase ◽

Disulfide Isomerase ◽

Protein Disulfide

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Faculty Opinions recommendation of Protein disulfide-isomerase mediates delivery of nitric oxide redox derivatives into platelets.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1088121.541113 ◽

2007 ◽

Author(s):

Peter Taylor

Keyword(s):

Nitric Oxide ◽

Protein Disulfide Isomerase ◽

Disulfide Isomerase ◽

Protein Disulfide

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Faculty Opinions recommendation of A critical role for extracellular protein disulfide isomerase during thrombus formation in mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1104838.560924 ◽

2008 ◽

Author(s):

Steve Watson

Keyword(s):

Protein Disulfide Isomerase ◽

Thrombus Formation ◽

Critical Role ◽

Extracellular Protein ◽

Disulfide Isomerase ◽

Protein Disulfide

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Faculty Opinions recommendation of Platelet protein disulfide isomerase is required for thrombus formation but not for hemostasis in mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718084608.793482672 ◽

2013 ◽

Author(s):

A Koneti Rao ◽

David Essex

Keyword(s):

Protein Disulfide Isomerase ◽

Thrombus Formation ◽

Disulfide Isomerase ◽

Platelet Protein ◽

Protein Disulfide

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Faculty Opinions recommendation of Extracellular protein disulfide isomerase regulates ligand-binding activity of αMβ2 integrin and neutrophil recruitment during vascular inflammation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718095306.793483028 ◽

2013 ◽

Author(s):

A Koneti Rao ◽

David Essex

Keyword(s):

Ligand Binding ◽

Protein Disulfide Isomerase ◽

Vascular Inflammation ◽

Binding Activity ◽

Neutrophil Recruitment ◽

Extracellular Protein ◽

Disulfide Isomerase ◽

Protein Disulfide ◽

Ligand Binding Activity

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Faculty Opinions recommendation of The transmembrane protein disulfide isomerase TMX1 negatively regulates platelet responses.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.734435822.793555036 ◽

2019 ◽

Author(s):

Toshiyuki Miyata

Keyword(s):

Protein Disulfide Isomerase ◽

Transmembrane Protein ◽

Disulfide Isomerase ◽

Protein Disulfide

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