Integration of 3D multimodal imaging data of a head and neck cancer and advanced feature recognition

2017 ◽  
Vol 1865 (7) ◽  
pp. 946-956 ◽  
Author(s):  
Judith M. Lotz ◽  
Franziska Hoffmann ◽  
Johannes Lotz ◽  
Stefan Heldmann ◽  
Dennis Trede ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Multimodal Imaging ◽  
Feature Recognition ◽  
Imaging Data

Kinetic modeling and numerical simulations to predict patient-specific responses to radiotherapy

2021 ◽  
pp. 2150083
Author(s):  
Liuyong Pang ◽  
Sanhong Liu ◽  
Zhong Zhao ◽  
XinYu Song ◽  
Xinan Zhang ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Treatment Strategies ◽  
Critical Factor ◽  
Patient Specific ◽  
Imaging Data ◽  
Short Treatment ◽  
Repair Capacity ◽  
Volumetric Imaging

Recent research indicates that quiescent tumor cells are significantly less radiosensitive with a greater repair capacity than proliferative cells. In order to better predict patient-specific responses to radiotherapy, we develop a mathematical model with treatment terms to describe dynamical behaviors of tumor growth. The global stabilities of the tumor-free equilibrium, the tumor-present equilibrium and the corresponding sufficient criteria are obtained. In addition, we simulate volumetric imaging data from 12 head-and-neck cancer patients and estimate the patient-specific responses to radiotherapy. Results indicate that radiosensitivity of proliferative cells is a critical factor that determines a successful radiotherapy. By comparison with previous simulation results, we find that the model presented in this paper is more suitable to describe the radiotherapy procedure of head-and-neck cancer. Finally, we discuss the influences of different radiotherapy strategies on therapeutic effect. The results show that treatment strategies with large dose or short treatment cycle can obtain better treatment effect.

Multimodal imaging analysis of an orthotopic head and neck cancer mouse model and application of anti-CD137 tumor immune therapy

Head & Neck ◽  
2015 ◽  
Vol 38 (4) ◽  
pp. 542-549 ◽  
Author(s):  
Anne-Kristin Vahle ◽  
Sven Hermann ◽  
Michael Schäfers ◽  
Michael Wildner ◽  
Alexander Kerem ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Mouse Model ◽  
Head And Neck ◽  
Neck Cancer ◽  
Multimodal Imaging ◽  
Immune Therapy ◽  
Imaging Analysis

Prognostic value of tumor volumetry data of routine imaging data in a head and neck cancer registry

2013 ◽  
Vol 271 (9) ◽  
pp. 2531-2537 ◽  
Author(s):  
Daniela Oemus ◽  
Johanna Inhestern ◽  
Harald Schmalenberg ◽  
Stefan Schultze-Mosgau ◽  
Hans-Joachim Mentzel ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Registry ◽  
Neck Cancer ◽  
Prognostic Value ◽  
Imaging Data ◽  
Tumor Volumetry ◽  
Routine Imaging

Nutritional status as a prognostic factor in advanced head and neck cancer

1998 ◽  
Vol 23 (4) ◽  
pp. 376-376
Author(s):  
Quak ◽  
Van Bokhorst ◽  
Klop ◽  
Van Leeuwen ◽  
Snow
Keyword(s):  
Head And Neck Cancer ◽  
Prognostic Factor ◽  
Nutritional Status ◽  
Head And Neck ◽  
Neck Cancer ◽  
Advanced Head
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