Analysis of the local dynamics of human insulin and a rapid-acting insulin analog by hydrogen/deuterium exchange mass spectrometry

Shiori Nakazawa; Joomi Ahn; Noritaka Hashii; Kenji Hirose; Nana Kawasaki

doi:10.1016/j.bbapap.2012.11.012

Analysis of the local dynamics of human insulin and a rapid-acting insulin analog by hydrogen/deuterium exchange mass spectrometry

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics ◽

10.1016/j.bbapap.2012.11.012 ◽

2013 ◽

Vol 1834 (6) ◽

pp. 1210-1214 ◽

Cited By ~ 11

Author(s):

Shiori Nakazawa ◽

Joomi Ahn ◽

Noritaka Hashii ◽

Kenji Hirose ◽

Nana Kawasaki

Keyword(s):

Mass Spectrometry ◽

Human Insulin ◽

Deuterium Exchange ◽

Insulin Analog ◽

Hydrogen Deuterium Exchange ◽

Local Dynamics ◽

Exchange Mass Spectrometry ◽

Acting Insulin ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry

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Detection of structural and conformational changes in ALS-causing mutant profilin-1 with hydrogen/deuterium exchange mass spectrometry and bioinformatics techniques

Metabolic Brain Disease ◽

10.1007/s11011-021-00763-y ◽

2021 ◽

Author(s):

Ahmad Shahir Sadr ◽

Zahra Abdollahpour ◽

Atousa Aliahmadi ◽

Changiz Eslahchi ◽

Mina Nekouei ◽

...

Keyword(s):

Mass Spectrometry ◽

Conformational Changes ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry

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Design and Validation of In-Source Atmospheric Pressure Photoionization Hydrogen/Deuterium Exchange Mass Spectrometry with Continuous Feeding of D2O

Journal of the American Society for Mass Spectrometry ◽

10.1007/s13361-017-1831-8 ◽

2017 ◽

Vol 29 (1) ◽

pp. 85-94 ◽

Cited By ~ 4

Author(s):

Thamina Acter ◽

Seulgidaun Lee ◽

Eunji Cho ◽

Maeng-Joon Jung ◽

Sunghwan Kim

Keyword(s):

Mass Spectrometry ◽

Atmospheric Pressure ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Atmospheric Pressure Photoionization ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry ◽

Continuous Feeding

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Different conformational dynamics of various active states of β-arrestin1 analyzed by hydrogen/deuterium exchange mass spectrometry

Journal of Structural Biology ◽

10.1016/j.jsb.2015.04.006 ◽

2015 ◽

Vol 190 (2) ◽

pp. 250-259 ◽

Cited By ~ 11

Author(s):

Dong Kyun Kim ◽

Youngjoo Yun ◽

Hee Ryung Kim ◽

Min-Duk Seo ◽

Ka Young Chung

Keyword(s):

Mass Spectrometry ◽

Conformational Dynamics ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry

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Hydrogen deuterium exchange mass spectrometry in biopharmaceutical discovery and development – A review

Analytica Chimica Acta ◽

10.1016/j.aca.2016.08.006 ◽

2016 ◽

Vol 940 ◽

pp. 8-20 ◽

Cited By ~ 36

Author(s):

Bin Deng ◽

Cristina Lento ◽

Derek J. Wilson

Keyword(s):

Mass Spectrometry ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry

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Hydrogen-Deuterium Exchange Mass Spectrometry of Phosphorylation Induced Changes in Smooth Muscle Myosin

Biophysical Journal ◽

10.1016/j.bpj.2012.11.2501 ◽

2013 ◽

Vol 104 (2) ◽

pp. 452a

Author(s):

K. Ilker Sen ◽

Brian D. Haldeman ◽

Richard Brizendine ◽

Roger Mercer ◽

Christine R. Cremo ◽

...

Keyword(s):

Mass Spectrometry ◽

Smooth Muscle ◽

Smooth Muscle Myosin ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry ◽

Induced Changes ◽

Muscle Myosin

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Deglycosylation induces extensive dynamics changes in α-amylase revealed by hydrogen/deuterium exchange mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.6732 ◽

2013 ◽

Vol 27 (23) ◽

pp. 2625-2630 ◽

Cited By ~ 4

Author(s):

Chengjie Ji ◽

Gary Wei

Keyword(s):

Mass Spectrometry ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry

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Research advances in hydrogen–deuterium exchange mass spectrometry for protein epitope mapping

Analytical and Bioanalytical Chemistry ◽

10.1007/s00216-020-03091-9 ◽

2021 ◽

Author(s):

Haofeng Sun ◽

Lingyun Ma ◽

Leyu Wang ◽

Peng Xiao ◽

Hongmei Li ◽

...

Keyword(s):

Mass Spectrometry ◽

Epitope Mapping ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry

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Moderated Test Statistics to Detect Differential Deuteration in Hydrogen/Deuterium Exchange Mass Spectrometry Experiments

Analytical Chemistry ◽

10.1021/acs.analchem.1c02346 ◽

2021 ◽

Author(s):

Jürgen Claesen ◽

Srinath Krishnamurthy ◽

Andy M. Lau ◽

Anastassios Economou

Keyword(s):

Mass Spectrometry ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Test Statistics ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry

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Cover Picture: Identification of Pharmacological Chaperones for Gaucher Disease and Characterization of Their Effects on β-Glucocerebrosidase by Hydrogen/Deuterium Exchange Mass Spectrometry (ChemBioChem 16/2008)

ChemBioChem ◽

10.1002/cbic.200890061 ◽

2008 ◽

Vol 9 (16) ◽

pp. 2549-2549

Author(s):

Michael B. Tropak ◽

Gregory J. Kornhaber ◽

Brigitte A. Rigat ◽

Gustavo H. Maegawa ◽

Justin D. Buttner ◽

...

Keyword(s):

Mass Spectrometry ◽

Gaucher Disease ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Pharmacological Chaperones ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry ◽

Picture Identification

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Vibrio cholerae Toxin-Coregulated Pilus Structure Analyzed by Hydrogen/Deuterium Exchange Mass Spectrometry

Structure ◽

10.1016/j.str.2007.10.027 ◽

2008 ◽

Vol 16 (1) ◽

pp. 137-148 ◽

Cited By ~ 51

Author(s):

Juliana Li ◽

Mindy S. Lim ◽

Sheng Li ◽

Melissa Brock ◽

Michael E. Pique ◽

...

Keyword(s):

Mass Spectrometry ◽

Vibrio Cholerae ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry ◽

Toxin Coregulated Pilus

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