Design and biophysical characterization of a monomeric four-alpha-helix bundle protein Aα4 with affinity for the volatile anesthetic halothane

2012 ◽  
Vol 1824 (12) ◽  
pp. 1409-1415
Author(s):  
Lucia Morstadt ◽  
Qing Cheng Meng ◽  
Jonas S. Johansson
Keyword(s):  
Volatile Anesthetic ◽  
Alpha Helix ◽  
Biophysical Characterization ◽  
Helix Bundle ◽  
Bundle Protein

Binding of Four General Anesthetics to the Hydrophobic Core of a Four-Alpha-Helix Bundle Protein

2002 ◽  
Vol 96 (Sup 2) ◽  
pp. A79
Author(s):  
Jonas S. Johansson ◽  
Gavin A. Manderson ◽  
Ravindernath Pidikiti ◽  
Roderic G. Eckenhoff
Keyword(s):  
Alpha Helix ◽  
Hydrophobic Core ◽  
General Anesthetics ◽  
Helix Bundle ◽  
Bundle Protein

scholarly journals Characterization of folding the four-helix bundle protein Rop by real-time NMR

2008 ◽  
Vol 21 (3) ◽  
pp. 165-170 ◽  
Author(s):  
N. A.J. van Nuland ◽  
C. M. Dobson ◽  
L. Regan
Keyword(s):  
Real Time ◽  
Helix Bundle ◽  
Four Helix Bundle ◽  
Bundle Protein

Expression and Characterization of a Four-α-Helix Bundle Protein That Binds the Volatile General Anesthetic Halothane

2005 ◽  
Vol 6 (3) ◽  
pp. 1516-1523 ◽  
Author(s):  
Ravindernath Pidikiti ◽  
Mohammad Shamim ◽  
Krishna M. G. Mallela ◽  
Konda S. Reddy ◽  
Jonas S. Johansson
Keyword(s):  
General Anesthetic ◽  
Helix Bundle ◽  
Α Helix ◽  
Bundle Protein

De novo design, expression, and characterization of Felix: a four-helix bundle protein of native-like sequence

Science ◽  
1990 ◽  
Vol 249 (4971) ◽  
pp. 884-891 ◽  
Author(s):  
M. Hecht ◽  
J. Richardson ◽  
D. Richardson ◽  
R. Ogden
Keyword(s):  
De Novo ◽  
De Novo Design ◽  
Helix Bundle ◽  
Four Helix Bundle ◽  
Bundle Protein

A DESIGNED THREE-[Greek small letter alpha]-HELIX BUNDLE SCAFFOLD FOR INCORPORATING VOLATILE ANESTHETIC BINDING SITES

1998 ◽  
Vol 89 (Supplement) ◽  
pp. 101A ◽  
Author(s):  
J S Johansson ◽  
B R Gibney ◽  
J J Skalicky ◽  
A J Wand ◽  
P L Dutton
Keyword(s):  
Binding Sites ◽  
Volatile Anesthetic ◽  
Alpha Helix ◽  
Small Letter ◽  
Helix Bundle

scholarly journals Computational De Novo Design and Characterization of a Four-Helix Bundle Protein that Selectively Binds a Nonbiological Cofactor [J.Am. Chem. Soc.2005,127, 1346−1347].

2006 ◽  
Vol 128 (2) ◽  
pp. 663-663 ◽  
Author(s):  
Frank V. Cochran ◽  
Sophia P. Wu ◽  
Wei Wang ◽  
Vikas Nanda ◽  
Jeffery G. Saven ◽  
...  
Keyword(s):  
De Novo ◽  
De Novo Design ◽  
Helix Bundle ◽  
Four Helix Bundle ◽  
Bundle Protein
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