Investigation of self-assembling proline- and glycine-rich recombinant proteins and peptides inspired by proteins from a symbiotic fungus using atomic force microscopy and circular dichroism spectroscopy

2012 ◽  
Vol 1824 (5) ◽  
pp. 711-722 ◽  
Author(s):  
Rhiannon G. Creasey ◽  
Nicolas H. Voelcker ◽  
Carolyn J. Schultz
Keyword(s):  
Atomic Force Microscopy ◽  
Circular Dichroism ◽  
Recombinant Proteins ◽  
Circular Dichroism Spectroscopy ◽  
Force Microscopy ◽  
Symbiotic Fungus ◽  
Self Assembling ◽  
Atomic Force ◽  
Circular Dichroïsm ◽  
Proteins And Peptides

Tunable Organogelator from Alkyl-Polypeptide Diblock Prepared by Ring-Opening Polymerization

2014 ◽  
Vol 67 (1) ◽  
pp. 59 ◽  
Author(s):  
Chongyi Chen ◽  
Decheng Wu ◽  
Wenxin Fu ◽  
Zhibo Li
Keyword(s):  
Atomic Force Microscopy ◽  
Organic Solvents ◽  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Low Concentration ◽  
Force Microscopy ◽  
Atomic Force ◽  
Transmission Electron ◽  
Circular Dichroïsm ◽  
Β Sheet

Three alkyl-polypeptide hybrid amphiphiles were synthesized by the ring-opening polymerization (ROP) of γ-(2-methoxyethoxy)esteryl-l-glutamate N-carboxyanhydride (l-EG1Glu NCA) using alkylamine, i.e. C6H13NH2, C14H29NH2, and C16H33NH2, as initiators. As-prepared alkyl-poly-l-EG1Glu hybrids were found to form clear organogels in several organic solvents at low concentration. FTIR and circular dichroism characterizations suggested that poly-l-EG1Glu formed a predominantly β-sheet conformation, which accounted for the gelation. Transmission electron and atomic force microscopy characterizations revealed that these copolymers formed nanoribbon structures in THF.

scholarly journals The Inhibitory Effect of Resveratrol on Elastin Amyloidogenesis

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Antonietta Pepe ◽  
Florian Delaunay ◽  
Angelo Bracalello ◽  
Brigida Bochicchio
Keyword(s):  
Molecular Structure ◽  
Atomic Force Microscopy ◽  
Self Assembly ◽  
Inhibitory Effect ◽  
Degenerative Diseases ◽  
Force Microscopy ◽  
Atomic Force ◽  
Circular Dichroïsm

The role of polyphenols in the prevention of degenerative diseases is emerging in the last years. In this report, we will investigate in vitro the inhibitory effect of resveratrol on elastin amyloidogenesis. The effect of resveratrol on molecular structure was investigated by circular dichroism spectroscopy, while the inhibitory effect on self-assembly was evaluated by turbidimetry as a function of temperature and by atomic force microscopy.

Reduction of ice adhesion to metal by using self-assembling monolayers (SAMs)

2003 ◽  
Vol 81 (1-2) ◽  
pp. 387-393 ◽  
Author(s):  
V F Petrenko ◽  
S Peng
Keyword(s):  
Contact Angle ◽  
Atomic Force Microscopy ◽  
Hydrogen Bonding ◽  
Molecular Layer ◽  
Hydrophobic Properties ◽  
Force Microscopy ◽  
Self Assembling ◽  
Atomic Force ◽  
Ice Adhesion

A new method has been developed to study the role of hydrogen bonding in ice adhesion and to minimize the effect of this mechanism on ice adhesion. Metals were coated with a mono-molecular layer that had either strong hydrophobic properties or strong hydrophilic properties. Self-assembling monolayers (SAMs) of varying degrees of hydrophobicity/hydrophilicity were created by mixing the hydrophobic and hydrophilic components. The SAM structure and quality were examined using atomic force microscopy, and the degree of the SAM hydrophobicity/hydrophilicity was characterized by the contact angle of water on the monolayer surfaces. Then, water was frozen on the top of the SAM and the shear strength of the interface between ice and SAM was measured. A good correlation between the contact angle of water and the ice adhesion strength was shown and the fraction of ice adhesion caused by hydrogen bonding was determined. It is revealed that hydrogen bonding significantly enhances ice adhesion. PACS No.: 61

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