Snake venom metalloproteinases: Structure, function and relevance to the mammalian ADAM/ADAMTS family proteins

2012 ◽  
Vol 1824 (1) ◽  
pp. 164-176 ◽  
Author(s):  
Soichi Takeda ◽  
Hiroyuki Takeya ◽  
Sadaaki Iwanaga
Keyword(s):  
Structure Function ◽  
Snake Venom

scholarly journals Anticoagulant proteins from snake venoms: structure, function and mechanism

2006 ◽  
Vol 397 (3) ◽  
pp. 377-387 ◽  
Author(s):  
R. Manjunatha Kini
Keyword(s):  
Structure Function ◽  
Blood Coagulation ◽  
Snake Venom ◽  
Molecular Mechanisms ◽  
Cerebrovascular Diseases ◽  
Clot Formation ◽  
Snake Venoms ◽  
New Anticoagulants ◽  
Physiological Processes ◽  
Made In

Over the last several decades, research on snake venom toxins has provided not only new tools to decipher molecular details of various physiological processes, but also inspiration to design and develop a number of therapeutic agents. Blood circulation, particularly thrombosis and haemostasis, is one of the major targets of several snake venom proteins. Among them, anticoagulant proteins have contributed to our understanding of molecular mechanisms of blood coagulation and have provided potential new leads for the development of drugs to treat or to prevent unwanted clot formation. Some of these anticoagulants exhibit various enzymatic activities whereas others do not. They interfere in normal blood coagulation by different mechanisms. Although significant progress has been made in understanding the structure–function relationships and the mechanisms of some of these anticoagulants, there are still a number of questions to be answered as more new anticoagulants are being discovered. Such studies contribute to our fight against unwanted clot formation, which leads to death and debilitation in cardiac arrest and stroke in patients with cardiovascular and cerebrovascular diseases, arteriosclerosis and hypertension. This review describes the details of the structure, mechanism and structure–function relationships of anticoagulant proteins from snake venoms.

Insights into the structure, function and stability of bordonein-L, the first L-amino acid oxidase from Crotalus durissus terrificus snake venom

Biochimie ◽  
2019 ◽  
Vol 163 ◽  
pp. 33-49 ◽  
Author(s):  
Gisele A. Wiezel ◽  
Joane K. Rustiguel ◽  
David Morgenstern ◽  
Karina F. Zoccal ◽  
Lucia H. Faccioli ◽  
...  
Keyword(s):  
Amino Acid ◽  
Structure Function ◽  
Snake Venom ◽  
Acid Oxidase ◽  
Amino Acid Oxidase ◽  
Crotalus Durissus Terrificus ◽  
Crotalus Durissus

Snake venom metalloproteinases: Structure, function and relationship to the ADAMs family of proteins

Toxicon ◽  
1996 ◽  
Vol 34 (11-12) ◽  
pp. 1269-1276 ◽  
Author(s):  
Li-Guo Jia ◽  
Ken-Ichi Shimokawa ◽  
Jon B. Bjarnason ◽  
Jay W. Fox
Keyword(s):  
Structure Function ◽  
Snake Venom ◽  
Adams Family

Structure–function inferences based on molecular modeling, sequence-based methods and biological data analysis of snake venom lectins

Toxicon ◽  
2006 ◽  
Vol 48 (6) ◽  
pp. 690-701 ◽  
Author(s):  
Paula Alvarez Abreu ◽  
Magaly Girão Albuquerque ◽  
Carlos Rangel Rodrigues ◽  
Helena Carla Castro
Keyword(s):  
Data Analysis ◽  
Molecular Modeling ◽  
Structure Function ◽  
Snake Venom ◽  
Biological Data ◽  
Biological Data Analysis

Structure-function studies on the bradykinin potentiating peptide from Chinese snake venom (Agkistrodon halys Pallas)

Peptides ◽  
1985 ◽  
Vol 6 ◽  
pp. 339-342 ◽  
Author(s):  
Chi Cheng-Wu ◽  
Wang Shou-Zhen ◽  
Xu Lai-Gen ◽  
Wang Mao-Ying ◽  
Lo Shan-Shan ◽  
...  
Keyword(s):  
Structure Function ◽  
Snake Venom

Structure-function study of a novel plasminogen activator from snake venom (Trimeresurus stejnegeri)

Toxicon ◽  
1997 ◽  
Vol 35 (12) ◽  
pp. 1661
Author(s):  
S. Braud ◽  
A. Wisner ◽  
R.C. Maroun ◽  
Y. Zhang ◽  
C. Bon
Keyword(s):  
Structure Function ◽  
Plasminogen Activator ◽  
Snake Venom ◽  
Function Study

Snake venom metalloproteinases: structure/function relationships studies using monoclonal antibodies

Toxicon ◽  
2003 ◽  
Vol 42 (7) ◽  
pp. 801-808 ◽  
Author(s):  
Isabelle Tanjoni ◽  
Diego Butera ◽  
Luciana Bento ◽  
Maisa S Della-Casa ◽  
Rafael Marques-Porto ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Structure Function ◽  
Snake Venom
Sign in / Sign up

Export Citation Format

Share Document