Frequency-domain analysis of linear systems with periodic jumps: Definition of hybrid transfer function, pole and zero

Automatica ◽  
2020 ◽  
Vol 112 ◽  
pp. 108690
Author(s):  
Sergio Galeani ◽  
Corrado Possieri ◽  
Mario Sassano
2017 ◽  
Vol 312 (5) ◽  
pp. H1076-H1084 ◽  
Author(s):  
Jun Sugawara ◽  
Tsubasa Tomoto ◽  
Tomoko Imai ◽  
Seiji Maeda ◽  
Shigehiko Ogoh

High cerebral pressure and flow fluctuations could be a risk for future cerebrovascular disease. This study aims to determine whether acute systemic vasoconstriction affects the dynamic pulsatile hemodynamic transmission from the aorta to the brain. We applied a stepwise lower body negative pressure (LBNP) (−10, −20, and −30 mmHg) in 15 young men to induce systemic vasoconstriction. To elucidate the dynamic relationship between the changes in aortic pressure (AoP; estimated from the radial arterial pressure waveforms) and the cerebral blood flow velocity (CBFV) at the middle cerebral artery (via a transcranial Doppler), frequency-domain analysis characterized the beat-to-beat slow oscillation (0.02–0.30 Hz) and the intra-beat rapid change (0.78–9.69 Hz). The systemic vascular resistance gradually and significantly increased throughout the LBNP protocol. In the low-frequency range (LF: 0.07–0.20 Hz) of a slow oscillation, the normalized transfer function gain of the steady-state component (between mean AoP and mean CBFV) remained unchanged, whereas that of the pulsatile component (between pulsatile AoP and pulsatile CBFV) was significantly augmented during −20 and −30 mmHg of LBNP (+28.8% and +32.4% vs. baseline). Furthermore, the relative change in the normalized transfer function gain of the pulsatile component at the LF range correlated with the corresponding change in systemic vascular resistance ( r = 0.41, P = 0.005). Regarding the intra-beat analysis, the normalized transfer function gain from AoP to CBFV was not significantly affected by the LBNP stimulation ( P = 0.77). Our findings suggest that systemic vasoconstriction deteriorates the dampening effect on the pulsatile hemodynamics toward the brain, particularly in slow oscillations (e.g., 0.07–0.20 Hz). NEW & NOTEWORTHY We characterized the pulsatile hemodynamic transmission from the heart to the brain by frequency-domain analysis. The low-frequency transmission was augmented with a mild LBNP stimulation partly due to the elevated systemic vascular resistance. A systemic vasoconstriction deteriorates the dampening effect on slow oscillations of pulsatile hemodynamics toward the brain.


1998 ◽  
Vol 18 (3) ◽  
pp. 311-318 ◽  
Author(s):  
Terry Bo-Jau Kuo ◽  
Chang-Ming Chern ◽  
Wen-Yung Sheng ◽  
Wen-Jang Wong ◽  
Han-Hwa Hu

We applied frequency domain analysis to detect and quantify spontaneous fluctuations in the blood flow velocity of the middle cerebral artery (MCAFV). Instantaneous MCAFV of normal volunteers was detected using transcranial Doppler sonography. Spectral and transfer function analyses of MCAFV and arterial blood pressure (ABP) were performed by fast Fourier transform. We found the fluctuations in MCAFV, like ABP, could be diffracted into three components at specific frequency ranges, designated as high-frequency (HF, 0.15 to 0.4 Hz), low-frequency (LF, 0.04 to 0.15 Hz), and very low-frequency (VLF, 0.016 to 0.04 Hz) components. The HF and LF components of MCAFV exhibited high coherence with those of ABP, indicating great similarity of MCAFV and ABP fluctuations within the two frequency ranges. However, it was not the case for the VLF component. Transfer function analysis revealed that the ABP-MCAFV phase angle was frequency-dependent in the LF range ( r = −0.79, P < 0.001) but not in the HF range. The time delay between LF fluctuations of ABP and those of MCAFV was evaluated as 2.1 seconds. We conclude that in addition to traditional B-wave equivalents, there are at least two different mechanisms for MCAFV fluctuations: the HF and LF fluctuations of MCAFV are basically secondary to those of ABP, and cerebral autoregulation may operate efficiently in LF rather than HF range. Frequency domain analysis offers an opportunity to explore the nature and underlying mechanism of dynamic regulation in cerebral circulation.


Energies ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3606
Author(s):  
Jing-Yuan Lin ◽  
Chuan-Ting Chen ◽  
Kuan-Hung Chen ◽  
Yi-Feng Lin

Three-phase wye–delta LLC topology is suitable for voltage step down and high output current, and has been used in the industry for some time, e.g., for server power and EV charger. However, no comprehensive circuit analysis has been performed for three-phase wye–delta LLC. This paper provides complete analysis methods for three-phase wye–delta LLC. The analysis methods include circuit operation, time domain analysis, frequency domain analysis, and state–plane analysis. Circuit operation helps determine the circuit composition and operation sequence. Time domain analysis helps understand the detail operation, equivalent circuit model, and circuit equation. Frequency domain analysis helps obtain the curve of the transfer function and assists in circuit design. State–plane analysis is used for optimal trajectory control (OTC). These analyses not only can calculate the voltage/current stress, but can also help design three-phase wye-delta connected LLC and provide the OTC control reference. In addition, this paper uses PSIM simulation to verify the correctness of analysis. At the end, a 5-kW three-phase wye–delta LLC prototype is realized. The specification of the prototype is a DC input voltage of 380 V and output voltage/current of 48 V/105 A. The peak efficiency is 96.57%.


Sign in / Sign up

Export Citation Format

Share Document