Rapid prototyping for hypervelocity impulse facility test models

2019 ◽  
Vol 88 ◽  
pp. 174-184 ◽  
Author(s):  
Steven F.T. Apirana ◽  
Christopher M. James ◽  
Robert Eldridge ◽  
Richard G. Morgan ◽  
Steven W. Lewis
Keyword(s):  
Rapid Prototyping ◽  
Test Models ◽  
Impulse Facility

Medical rapid prototyping (MRP) in adult- and paediatric cardiac surgery

2011 ◽  
Vol 59 (S 01) ◽  
Author(s):  
R Sodian ◽  
S Haeberle ◽  
S Weber ◽  
T Lueth ◽  
A Beiras-Fernandez ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Rapid Prototyping ◽  
Paediatric Cardiac Surgery

Defibrotide Inhibits Platelet Activation by Cathepsin G Released From Stimulated Polymorphonuclear Leukocytes

1992 ◽  
Vol 67 (06) ◽  
pp. 660-664 ◽  
Author(s):  
Virgilio Evangelista ◽  
Paola Piccardoni ◽  
Giovanni de Gaetano ◽  
Chiara Cerletti
Keyword(s):  
Platelet Activation ◽  
Polymorphonuclear Leukocytes ◽  
Direct Interaction ◽  
Cathepsin G ◽  
In Vivo Test ◽  
Cell Functions ◽  
Test Models ◽  
Antithrombotic Effects

SummaryDefibrotide is a polydeoxyribonucleotide with antithrombotic effects in experimental animal models. Most of the actions of this drug have been observed in in vivo test models but no effects have been reported in in vitro systems. In this paper we demonstrate that defibrotide interferes with polymorphonuclear leukocyte-induced human platelet activation in vitro. This effect was not related to any direct interaction with polymorphonuclear leukocytes or platelets, but was due to the inhibition of cathepsin G, the main biochemical mediator of this cell-cell cooperation. Since cathepsin G not only induces platelet activation but also affects some endothelial cell functions, the anticathepsin G activity of defibrotide could help to explain the antithrombotic effect of this drug.

USE OF RAPID PROTOTYPING IN PRODUCT DEVELOPMENT: A Case Study for Tool Manufacturing for Aeronautical Use

2017 ◽  
Vol 8 (5) ◽  
pp. 1-17
Author(s):  
Aires Jorge Alberto Sandi ◽  
◽  
Giacaglia Giorgio Eugenio Oscare ◽  
Keyword(s):  
Product Development ◽  
Rapid Prototyping

APPLYING THE ISF TECHNOLOGY TO PRODUCE THE CAR PART MODELS

2010 ◽  
Vol 13 (4) ◽  
pp. 91-98
Author(s):  
Tuan Dinh Phan ◽  
Binh Thien Nguyen ◽  
Dien Khanh Le ◽  
Phuong Hoang Pham
Keyword(s):  
Rapid Prototyping ◽  
Incremental Sheet Forming ◽  
Cad Model ◽  
Post Processing ◽  
Technological Parameters ◽  
Batch Production ◽  
Complex Products ◽  
3D Cad ◽  
Real Size ◽  
Single Batch

The paper presents an application the research results previously done by group on the influence of technological parameters to the deformation angle and finish surface quality in order to choose technology parameters for the incremental sheet forming (ISF) process to produce products for the purpose of rapid prototyping or single-batch production, including all steps from design and process 3D CAD model, calculate and select the technological parameters, setting up manufacturing and the stage of post-processing. The samples formed successfully showed high applicability of this technology to practical work, the complex products with the real size can be produced in industries: automotive, motorcycle, civil...

Dynamic Emulation of a Vehicle Seat Using HIL and Rapid Prototyping

2015 ◽  
Vol 9 (5) ◽  
pp. 499
Author(s):  
Angie Julieth Valencia Castañeda ◽  
Nicolás Linares Ospina ◽  
Dario Amaya Hurtado
Keyword(s):  
Rapid Prototyping ◽  
Dynamic Emulation ◽  
Vehicle Seat
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