Does Vitamin E–Stabilized Ultrahigh-Molecular-Weight Polyethylene Address Concerns of Cross-Linked Polyethylene in Total Knee Arthroplasty?

2012 ◽  
Vol 27 (3) ◽  
pp. 461-469 ◽  
Author(s):  
Hani Haider ◽  
Joel N. Weisenburger ◽  
Steven M. Kurtz ◽  
Clare M. Rimnac ◽  
Jordan Freedman ◽  
...  
1998 ◽  
Vol 13 (1) ◽  
pp. 8-16 ◽  
Author(s):  
Markus A. Wimmer ◽  
Thomas P. Andriacchi ◽  
Raghu N. Natarajan ◽  
Joachim Loos ◽  
Matthias Karlhuber ◽  
...  

1984 ◽  
Vol 18 (2) ◽  
pp. 207-224 ◽  
Author(s):  
Robert M. Rose ◽  
Michael D. Ries ◽  
Igor L. Paul ◽  
Aldo M. Crugnola ◽  
Edward Ellis

1985 ◽  
Vol 55 ◽  
Author(s):  
Timothy M. Wright ◽  
Clare M. Rimnac ◽  
Donald L. Bartel

ABSTRACTThis article reviews the problem of ultrahigh molecular weight polyethylene component surface degradation in total hip and total knee prostheses, including its clinical implications. Several factors affecting surface damage have been identified from a combination of the observations of in-vivo degradation made on retrieved components, experimental measurement of contact stresses on polyethylene components as a result of contact with their metallic counterpart, and analytical studies of both contact stress and the stresses beneath the polyethylene surface. Both the observations of in-vivo surface degradation and the analytical studies demonstrate that surface degradation is a more severe problem in total knee replacements than in total hip replacements. The performance of polyethylene components, as affected by design factors such as material thickness and material modification, is also considered.


1998 ◽  
Vol 79 (05) ◽  
pp. 902-906 ◽  
Author(s):  
Andrew W. Howard ◽  
Shawn D. Aaron

SummaryObjectives: To assess the efficacy and safety of low molecular weight heparin (LMWH) as deep venous thrombosis (DVT) prophylaxis following total knee arthroplasty. Data sources: Medline 1986 to June 1997, Embase, and manufacturers were used to identify randomized controlled trials. Review methods: Trials included were randomized studies of LMWH with routine radiological screening for DVT. Placebo or active controls were included. Two reviewers independently screened trials for inclusion, and assessed their quality. Pooled relative risk estimates of DVT and proximal DVT rates were calculated using a DerSimonian and Laird random effects model. Sensitivity of the results to the type of control used and the quality of the trial was assessed. Results: The relative risk of DVT for a patient given LMWH is 0.73 (95% CI 0.66 to 0.80) when compared with patients treated with adjusted dose heparin or warfarin controls. The relative risk for proximal DVT is 0.58 (95% CI 0.38 to 0.90). The relative risk of pulmonary emboli in the LMWH group was 0.55 (95% C.I. 0.20 to 1.57). No excess of bleeding was recorded in the LMWH group. Conclusions: Low molecular weight heparin is more efficacious than either adjusted dose heparin or adjusted dose warfarin, when used to prevent DVT and proximal DVT following total knee arthroplasty.


2009 ◽  
Vol 2009.6 (0) ◽  
pp. 297-298
Author(s):  
Daisuke HAMADA ◽  
Yasushi OKUBO ◽  
Koji YAMAMOTO ◽  
Shin-ichiro MORI ◽  
Kunihiko FUJIWARA ◽  
...  

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