Self-assembly behavior of amphiphilic poly(ethylene glycol)-conjugated 10-hydroxycamptothecin in water and its cytotoxicity assay

2018 ◽  
Vol 459 ◽  
pp. 749-759 ◽  
Author(s):  
Yongfang Zhang ◽  
Xiaoxia Yang ◽  
Zhenning Lu ◽  
Haiping Li ◽  
Xiuli Guo ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Self Assembly ◽  
Cytotoxicity Assay ◽  
Poly Ethylene Glycol ◽  
Assembly Behavior ◽  
Poly Ethylene

Synthesis and thermo-responsive self-assembly behavior of amphiphilic copolymer β-CD–(PCL–P(MEO2MA-co-PEGMA))21 for the controlled intracellular delivery of doxorubicin

RSC Advances ◽  
2016 ◽  
Vol 6 (56) ◽  
pp. 50993-51004 ◽  
Author(s):  
Beibei Lu ◽  
Lei Li ◽  
Lulu Wei ◽  
Xuhong Guo ◽  
Jun Hou ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Self Assembly ◽  
Intracellular Delivery ◽  
Amphiphilic Copolymer ◽  
Poly Ethylene Glycol ◽  
Glycol Methacrylate ◽  
Ethyl Methacrylate ◽  
Assembly Behavior ◽  
Poly Ethylene

Well-defined amphiphilic β-cyclodextrin star-shaped copolymers with poly(ε-caprolactone)–poly(2-(2-methoxyethoxy)ethyl methacrylate)-co-poly(ethylene glycol)methacrylate) (β-CD–(PCL–P(MEO2MA-co-PEGMA))21 were synthesized via (ROP) and (ATRP).

Study on polymeric micelles of poly(γ-benzyl l-glutamate)-graft-poly(ethylene glycol) copolymer and its mixtures with poly(γ-benzyl l-glutamate) homopolymer in ethanol

2009 ◽  
Vol 63 (6) ◽  
Author(s):  
Guo-Quan Zhu
Keyword(s):  
Critical Micelle Concentration ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
Polymeric Micelles ◽  
Mixed System ◽  
Cylindrical Shape ◽  
Poly Ethylene Glycol ◽  
Assembly Behavior ◽  
Ester Exchange Reaction ◽  
Poly Ethylene

AbstractPoly(γ-benzyl l-glutamate)-graft-poly(ethylene glycol) (PBLG-graft-PEG) copolymer was synthesized by the ester exchange reaction of the PBLG homopolymer with PEG. NMR spectroscopy was used to confirm the composition of the PBLG-graft-PEG copolymer. FTIR spectroscopy was used to characterize the chain conformation of polypeptide segments in the PBLG-graft-PEG copolymer in solid state. The self-assembly behavior of PBLG-graft-PEG and its mixtures with PBLG in ethanol were investigated by transmission electron microscopy (TEM) and viscometry. Experimental results showed that the PBLG-graft-PEG copolymer can self-assemble to form polymeric micelles with a core-shell structure of a thin shuttle-like shape. The introduction of the PBLG homopolymer into the mixed system not only decreases the critical micelle concentration (CMC) but also changes the morphology of the micelles from their shuttle-like shape to cylindrical shape. The effects of test temperature on the critical micelle concentration of PBLG-graft-PEG were also studied.

Self-assembly behavior of gels composed of dibenzylidene sorbitol derivatives and poly(ethylene glycol)

RSC Advances ◽  
2016 ◽  
Vol 6 (100) ◽  
pp. 98042-98051 ◽  
Author(s):  
Wei-Chi Lai ◽  
Yi-Chin Lee
Keyword(s):  
Ethylene Glycol ◽  
Intermolecular Interactions ◽  
Self Assembly ◽  
Regular Structure ◽  
Poly Ethylene Glycol ◽  
Assembly Behavior ◽  
Poly Ethylene

The strongest intermolecular interactions between DBS molecules in the DBS/PEG systems led to the more regular structure compared with the DMDBS/PEG and TBPMN/PEG systems.

Self-assembly behavior of well-defined polymethylene-block-poly(ethylene glycol) copolymers in aqueous solution

Polymer ◽  
2016 ◽  
Vol 107 ◽  
pp. 415-421 ◽  
Author(s):  
Nazeeha Alkayal ◽  
George Zapsas ◽  
Panayiotis Bilalis ◽  
Nikos Hadjichristidis
Keyword(s):  
Aqueous Solution ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
Poly Ethylene Glycol ◽  
Assembly Behavior ◽  
Poly Ethylene

Synthesis and self-assembly behaviour of poly(Nα-Boc-l-tryptophan)-block-poly(ethylene glycol)-block-poly(Nα-Boc-l-tryptophan)

RSC Advances ◽  
2016 ◽  
Vol 6 (29) ◽  
pp. 24142-24153
Author(s):  
Andreea S. Voda ◽  
Kevin Magniez ◽  
Nisa V. Salim ◽  
Cynthia Wong ◽  
Qipeng Guo
Keyword(s):  
Drug Delivery ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
Triblock Copolymers ◽  
Potential Drug ◽  
Poly Ethylene Glycol ◽  
Drug Delivery Applications ◽  
Poly Ethylene ◽  
First Time

We report for the first time the use of Nα-Boc-l-tryptophan for the synthesis of amphiphilic BAB triblock copolymers for potential drug delivery applications.

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