Surface plasmon resonance imaging validation of small molecule drugs binding on target protein microarrays

2018 ◽  
Vol 450 ◽  
pp. 328-335 ◽  
Author(s):  
Wenfei Zhou ◽  
Mo Yang ◽  
Shaopeng Li ◽  
Jinsong Zhu
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Small Molecule ◽  
Plasmon Resonance ◽  
Protein Microarrays ◽  
Target Protein ◽  
Surface Plasmon Resonance Imaging ◽  
Resonance Imaging ◽  
Small Molecule Drugs

scholarly journals Small molecule microarray screening methodology based on surface plasmon resonance imaging

2019 ◽  
Vol 12 (8) ◽  
pp. 2111-2117 ◽  
Author(s):  
Vikramjeet Singh ◽  
Kuldeep Singh ◽  
Amita Nand ◽  
Huanqin Dai ◽  
Jianguo Wang ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Small Molecule ◽  
Plasmon Resonance ◽  
Surface Plasmon Resonance Imaging ◽  
Resonance Imaging ◽  
Microarray Screening

High-throughput measurement of drug–cyclodextrin kinetic rate constants by a small molecule microarray using surface plasmon resonance imaging

RSC Advances ◽  
2016 ◽  
Vol 6 (4) ◽  
pp. 3213-3218 ◽  
Author(s):  
Vikramjeet Singh ◽  
Zhuo Li ◽  
Xiaotong Zhou ◽  
Xiaonan Xu ◽  
Jianghui Xu ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Small Molecule ◽  
High Throughput ◽  
Plasmon Resonance ◽  
Rate Constants ◽  
Surface Plasmon Resonance Imaging ◽  
Resonance Imaging ◽  
Kinetic Rate ◽  
Kinetic Rate Constants

A high-throughput methodology for the measurement of drug–CD kinetic rate constants.

scholarly journals Retraction: 3D small molecule microarray with enhanced sensitivity and immobilization capacity monitored by surface plasmon resonance imaging

RSC Advances ◽  
2016 ◽  
Vol 6 (116) ◽  
pp. 115345-115345
Author(s):  
Jinsong Zhu
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Small Molecule ◽  
Plasmon Resonance ◽  
Surface Plasmon Resonance Imaging ◽  
Resonance Imaging ◽  
Enhanced Sensitivity

Retraction of ‘3D small molecule microarray with enhanced sensitivity and immobilization capacity monitored by surface plasmon resonance imaging’ by Vikramjeet Singh et al., RSC Adv., 2014, DOI: 10.1039/c4ra07306a.

Small-Molecule (Micro)arrays for Sensitive Multiplex Metabolites Detection by Surface Plasmon Resonance Imaging

2018 ◽  
Author(s):  
Yong Cao ◽  
Mark T. McDermott
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Small Molecule ◽  
Plasmon Resonance ◽  
Surface Plasmon Resonance Imaging ◽  
Resonance Imaging ◽  
Low Sensitivity ◽  
Small Molecule Detection ◽  
First Time

<div> <div> <div> <p>Small-molecule (micro)arrays were developed to measure three metabolites simultaneously by surface plasmon resonance imaging for the first time. To tackle the low sensitivity challenge associated with small molecule detection, antibodies were employed as the signal amplifiers. This work demonstrates both inhibition and displacement formats are applicable for sensitive multiplex metabolites detection. </p> </div> </div> </div>

Small-Molecule (Micro)arrays for Sensitive Multiplex Metabolites Detection by Surface Plasmon Resonance Imaging

2018 ◽  
Author(s):  
Yong Cao ◽  
Mark T. McDermott
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Small Molecule ◽  
Plasmon Resonance ◽  
Surface Plasmon Resonance Imaging ◽  
Resonance Imaging ◽  
Low Sensitivity ◽  
Small Molecule Detection ◽  
First Time

<div> <div> <div> <p>Small-molecule (micro)arrays were developed to measure three metabolites simultaneously by surface plasmon resonance imaging for the first time. To tackle the low sensitivity challenge associated with small molecule detection, antibodies were employed as the signal amplifiers. This work demonstrates both inhibition and displacement formats are applicable for sensitive multiplex metabolites detection. </p> </div> </div> </div>

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