In-vitro biocompatibility and corrosion resistance of electrochemically assembled PPy/TNTA hybrid material for biomedical applications

2018 ◽  
Vol 445 ◽  
pp. 320-334 ◽  
Author(s):  
V.S. Simi ◽  
Aishwarya Satish ◽  
Purna Sai Korrapati ◽  
N. Rajendran
Keyword(s):  
Corrosion Resistance ◽  
Hybrid Material ◽  
Biomedical Applications ◽  
In Vitro Biocompatibility

scholarly journals Surface Properties and Biocompatibility of Anodized Titanium with a Potential Pretreatment for Biomedical Applications

Metals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1090
Author(s):  
Bai-Hung Huang ◽  
Yi-Jung Lu ◽  
Wen-Chien Lan ◽  
Muhammad Ruslin ◽  
Hung-Yang Lin ◽  
...  
Keyword(s):  
Porous Structure ◽  
Biomedical Applications ◽  
Grazing Incidence ◽  
Acid Pretreatment ◽  
Osteoblast Cells ◽  
In Vitro Biocompatibility ◽  
Porous Ti ◽  
Diphenyltetrazolium Bromide ◽  
Anodized Titanium

The effects of anodized titanium (Ti) with a potential hydrogen fluoride (HF) acid pretreatment through cathodization on the formation of nano-porous Ti dioxide (TiO2) layer were characterized using field-emission scanning electron microscopy, grazing incidence X-ray diffractometer, and contact angle goniometer. The biocompatibility was determined by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) test. Analytical results found that a well-aligned nano-porous structure was formed on the anodized Ti surface with HF pretreatment concentration above 0.5%. Microstructure of the nano-porous Ti dioxide surface generated by anodization with HF pretreatment was composed of anatase and rutile phases, while the anodized Ti sample with HF pretreatment concentration of 0.5% presented excellent hydrophilicity surface. An in-vitro biocompatibility also indicated that osteoblast cells grown on the surface of the anodized Ti sample with HF pretreatment increased with the increase of culture time. The filopodia of osteoblast cells not only adhered flat, but also tightly grabbed the nano-porous structure for promoting cell adhesion and proliferation. Therefore, the anodized Ti with HF pretreatment can form a functionalized surface with great biocompatibility for biomedical applications, particularly for dental implants.

Characterization of NiCrMo Dental Restoration Alloy

2021 ◽  
Vol 875 ◽  
pp. 373-378
Author(s):  
Ali Haider ◽  
Omar Farooq Azam ◽  
Muhammad Talha ◽  
Saleem Akhtar
Keyword(s):  
Mechanical Properties ◽  
Corrosion Resistance ◽  
Dental Materials ◽  
Dental Restoration ◽  
Restorative Material ◽  
Nicr Alloy ◽  
In Vitro Biocompatibility ◽  
Dental Prostheses ◽  
Materials Used

Restorative material is a class of dental materials used for direct filling and fabrication of indirect restoration. NiCr alloy is a restorative material frequently used for dental prostheses due to its properties and economic reasons. In present work beryllium free NiCrMo alloy was developed and studied for dental restoration application. The alloy have unique characteristics of resistance to oxidation and biocompatibility; the requisites for dental prostheses. NiCrMo alloy is found to possess mechanical strength and fabrication properties suitable for dental repairs. In this study the developed alloy was tested for its mechanical properties, biocompatibility and corrosion resistance. An in-vitro biocompatibility study was carried out. No signs of toxicity and no signs of cell growth inhibition, in presence of NiCrMo alloy specimen, were observed. Mechanical properties and corrosion resistance are found in the range that is suitable for dental prostheses and easy fabrication.

3D Printed PLA/PCL/TiO2 Composite for Bone Replacement and Grafting

MRS Advances ◽  
2018 ◽  
Vol 3 (40) ◽  
pp. 2373-2378 ◽  
Author(s):  
Sandra E. Nájera ◽  
Monica Michel ◽  
Nam-Soo Kim
Keyword(s):  
Biomedical Applications ◽  
Fused Deposition Modeling ◽  
Fracture Strain ◽  
Fused Deposition ◽  
In Vitro Biocompatibility ◽  
Bone Replacement ◽  
Deposition Modeling ◽  
3D Printed ◽  
The Stability

ABSTRACTPolymer composites of Polylactic acid (PLA) and poly-ε-caprolactone (PCL), containing small amounts of titanium oxide (TiO2) were developed for biomedical applications. These composite materials were prepared, and then printed using Fused Deposition Modeling (FDM). 3D printed structures were characterized to determine their mechanical properties and biocompatibility. DSC analysis yielded useful information regarding the immiscibility of the different polymers, and it was observed that the particles of TiO2 improved the stability of the polymers. The ultimate tensile strength and the fracture strain increased by adding TiO2 as a filler, resulting in values of approximately 45 MPa and 5.5 % elongation. The printed composites show excellent in vitro biocompatibility including cell proliferation and adhesion, and are therefore promising candidates to be used in the biomedical field for bone replacement procedures, due to their properties similar to those of cancellous bone.

Enhanced Biocompatibility of GPC by Ion Implantation and Deposition

2005 ◽  
Vol 908 ◽  
Author(s):  
Robert Lee Zimmerman ◽  
Ismet Gürhan ◽  
Claudiu I. Muntele ◽  
Daryush Ila ◽  
Feyzan Özdal-Kurt ◽  
...  
Keyword(s):  
Ion Implantation ◽  
Biomedical Applications ◽  
Heart Valves ◽  
Cell Attachment ◽  
Blood Stream ◽  
Silver Deposition ◽  
In Vitro Biocompatibility ◽  
Artificial Heart Valves ◽  
Model Cell

AbstractBiocompatible Glassy Polymeric Carbon (GPC) is used for artificial heart valves and in other biomedical applications. Although it is ideally suited for implants in the blood stream, tissue that normally forms around the moving parts of a GPC heart valve sometimes loses adhesion and creates embolisms downstream. Here we compare silver ion implantation and silver deposition, each of which strongly inhibits cell attachment on GPC. Inhibition of cell adhesion is a desirable improvement to current GPC cardiac implants. In vitro biocompatibility tests have been carried out with model cell lines to demonstrate that traces of silver can favorably influence the surface of GPC for biomedical applications.

In vitro biocompatibility and corrosion resistance of a new implant titanium base alloy

2010 ◽  
Vol 21 (6) ◽  
pp. 1959-1968 ◽  
Author(s):  
E. Vasilescu ◽  
P. Drob ◽  
D. Raducanu ◽  
V. D. Cojocaru ◽  
I. Cinca ◽  
...  
Keyword(s):  
Corrosion Resistance ◽  
Base Alloy ◽  
In Vitro Biocompatibility

scholarly journals Surface Characterization, Corrosion Resistance and in Vitro Biocompatibility of a New Ti‐Hf‐Mo‐Sn Alloy

Materials ◽  
2016 ◽  
Vol 9 (10) ◽  
pp. 818 ◽  
Author(s):  
Raluca Ion ◽  
Silviu Drob ◽  
Muhammad Ijaz ◽  
Cora Vasilescu ◽  
Petre Osiceanu ◽  
...  
Keyword(s):  
Corrosion Resistance ◽  
Surface Characterization ◽  
In Vitro Biocompatibility

scholarly journals Oxytetracycline versus Doxycycline Collagen Sponges Designed as Potential Carrier Supports in Biomedical Applications

Pharmaceutics ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 363 ◽  
Author(s):  
Tihan ◽  
Rău ◽  
Zgârian ◽  
Ungureanu ◽  
Barbaresso ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Structural Integrity ◽  
Release Kinetics ◽  
Collagen Sponge ◽  
Application Site ◽  
Cross Linking ◽  
Drug Kinetic ◽  
In Vitro Biocompatibility ◽  
Kinetic Release

Many research studies are directed toward developing safe and efficient collagen-based biomaterials as carriers for drug delivery systems. This article presents a comparative study of the properties of new collagen sponges prepared and characterized by different methods intended for biomedical applications. The structural integrity is one of the main properties for a biomaterial in order for it to be easily removed from the treated area. Thus, the effect of combining a natural polymer such as collagen with an antimicrobial drug such as oxytetracycline or doxycycline and glutaraldehyde as the chemical cross-linking agent influences the cross-linking degree of the material, which is in direct relation to its resistance to collagenase digestion, the drug kinetic release profile, and in vitro biocompatibility. The enzymatic degradation results identified oxytetracycline as the best inhibitor of collagenase when the collagen sponge was cross-linked with 0.5% glutaraldehyde. The drug release kinetics revealed an extended release of the antibiotic for oxytetracycline-loaded collagen sponges compared with doxycycline-loaded collagen sponges. Considering the behavior of differently prepared sponges, the collagen sponge with oxytetracycline and 0.5% glutaraldehyde could represent a viable polymeric support for the prevention/treatment of infections at the application site, favoring tissue regeneration.

Preparation and Properties of Fluoride-Coated Mg-Zn-Zr Alloy for Biodegradable Intravascular Stents

2011 ◽  
Vol 287-290 ◽  
pp. 1970-1975
Author(s):  
Xin Yu Ye ◽  
Min Fang Chen ◽  
De Bao Liu ◽  
Meng Yang ◽  
Jun Wei
Keyword(s):  
Corrosion Resistance ◽  
Fine Particles ◽  
Corrosion Current ◽  
Cell Number ◽  
Electrochemical Tests ◽  
In Vitro Biocompatibility ◽  
Intravascular Stents ◽  
Surface Morphologies ◽  
Zr Alloy

In order to improve the corrosion resistance, the samples made of Mg-Zn-Zr alloy were immersed in 20% or 40% hydrofluoric acid (HF) aqueous solutions for different intervals to prepare magnesium fluoride (MgF2) coating on the surface. By comparing the surface morphologies, the samples immersed in 20% HF solution for 6 h on which fine particles in nanoscale covered was selected for the further study. Immersion and electrochemical tests showed that the dense MgF2 coating would improve the corrosion resistance of Mg-Zn-Zr alloy. The corrosion current density (icorr) decreased from 2.10 μA·cm-2 to 0.05 μA·cm-2. The influence of HF treatment on the cytocompatibility was evaluated in vitro. There were significant differences in the cell number between the naked and coated samples after culturing for 3 and 5 days (p<0.05). All the results demonstrate that HF treatment is a promising approach to improve the corrosion resistance and in vitro biocompatibility of Mg-Zn-Zr alloy used as intravascular stents.

Sign in / Sign up

Export Citation Format

Share Document