Optimizing the plasmonic sensing of RNA folding based on local refractive index change of gold nanorod

2013 ◽  
Vol 275 ◽  
pp. 264-268 ◽  
Author(s):  
Jian Zhu ◽  
Jian-jun Li ◽  
Jun-wu Zhao
Keyword(s):  
Refractive Index ◽  
Rna Folding ◽  
Refractive Index Change ◽  
Gold Nanorod ◽  
Index Change ◽  
Plasmonic Sensing ◽  
Local Refractive Index

Theoretical Investigation of Surface Plasmon Resonance (SPR)-Based Acoustic Sensor

2017 ◽  
Vol 866 ◽  
pp. 370-374
Author(s):  
Supannee Learkthanakhachon ◽  
Suejit Pechprasarn ◽  
Manas Sangworasil ◽  
Michael G. Somekh ◽  
Naphat Albutt
Keyword(s):  
Refractive Index ◽  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Theoretical Investigation ◽  
Plasmon Resonance ◽  
Refractive Index Change ◽  
Acoustic Sensor ◽  
Water Density ◽  
Index Change ◽  
Local Refractive Index

We report a theoretical investigation of a surface plasmon resonance (SPR)-based acoustic sensor for optical detection of ultrasound. The structure being studied is arranged in the Krestchmann configuration and the detection is performed by observing the change of refractive index of water next to the SPR metal. The acoustic pressure is simulated using COMSOL. The simulation results illustrate an insight into mechanism of pressure variation on the surface of SPR sensor due to a constructive interference of the ultrasound. This leads to a local refractive index change of water. The local refractive index change is calculated by converting the incident pressure to water density using IAPWS-95 formulation. Then, the water density is converted to the refractive index using Lorentz-Lorenz formulation. Here we report the change in the refractive index of the water to pressure, dn/dp, which is calculated to be 1.4 x 10-10 Pa-1, which is very close to the dn/dp reported by M. W. Sigrist 1986. We also investigated the effect of temperature and wavelength on the dn/dp and found that the variation in temperature and wavelength does not show any significant effect on the dn/dp relationship. We also discuss the effect of quality factor (Q) and possible improvements to enhance the sensitivity of SPR-based acoustic sensor.

Tuning the plasmon resonance of gold nanoparticles in phase-separated glass via the local refractive index change

2021 ◽  
Vol 566 ◽  
pp. 120893
Author(s):  
G. Shakhgildyan ◽  
L. Avakyan ◽  
M. Ziyatdinova ◽  
G. Atroshchenko ◽  
N. Presnyakova ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Refractive Index ◽  
Plasmon Resonance ◽  
Refractive Index Change ◽  
Index Change ◽  
Local Refractive Index

scholarly journals Morphological and in situ local refractive index change induced tuning of the optical properties of titania coated porous gold nanoparticles

2020 ◽  
Vol 128 (5) ◽  
pp. 054303
Author(s):  
Laura Juhász ◽  
Bence Parditka ◽  
Shenouda Shanda Shenouda ◽  
Misumi Kadoi ◽  
Kei-ichi Fukunaga ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Refractive Index ◽  
Optical Properties ◽  
Refractive Index Change ◽  
Index Change ◽  
Porous Gold ◽  
Local Refractive Index

scholarly journals Critical angle reflection imaging for quantification of molecular interactions on glass surface

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Guangzhong Ma ◽  
Runli Liang ◽  
Zijian Wan ◽  
Shaopeng Wang
Keyword(s):  
Refractive Index ◽  
Small Molecule ◽  
Molecular Interactions ◽  
Glass Surface ◽  
Critical Angle ◽  
Dynamic Range ◽  
Refractive Index Change ◽  
Label Free ◽  
Index Change ◽  
Sensing Range

AbstractQuantification of molecular interactions on a surface is typically achieved via label-free techniques such as surface plasmon resonance (SPR). The sensitivity of SPR originates from the characteristic that the SPR angle is sensitive to the surface refractive index change. Analogously, in another interfacial optical phenomenon, total internal reflection, the critical angle is also refractive index dependent. Therefore, surface refractive index change can also be quantified by measuring the reflectivity near the critical angle. Based on this concept, we develop a method called critical angle reflection (CAR) imaging to quantify molecular interactions on glass surface. CAR imaging can be performed on SPR imaging setups. Through a side-by-side comparison, we show that CAR is capable of most molecular interaction measurements that SPR performs, including proteins, nucleic acids and cell-based detections. In addition, we show that CAR can detect small molecule bindings and intracellular signals beyond SPR sensing range. CAR exhibits several distinct characteristics, including tunable sensitivity and dynamic range, deeper vertical sensing range, fluorescence compatibility, broader wavelength and polarization of light selection, and glass surface chemistry. We anticipate CAR can expand SPR′s capability in small molecule detection, whole cell-based detection, simultaneous fluorescence imaging, and broader conjugation chemistry.

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