Enhanced in vitro biocompatibility of ultrafine-grained titanium with hierarchical porous surface

2011 ◽  
Vol 257 (13) ◽  
pp. 5634-5640 ◽  
Author(s):  
C.Y. Zheng ◽  
F.L. Nie ◽  
Y.F. Zheng ◽  
Y. Cheng ◽  
S.C. Wei ◽  
...  
Keyword(s):  
Porous Surface ◽  
In Vitro Biocompatibility ◽  
Ultrafine Grained ◽  
Hierarchical Porous

scholarly journals Fabrication of a Promising Hierarchical Porous Surface on Titanium for Promoting Biocompatibility

2020 ◽  
Vol 10 (4) ◽  
pp. 1363 ◽  
Author(s):  
Wen-Chien Lan ◽  
Chia-Hsien Wang ◽  
Bai-Hung Huang ◽  
Yen-Chun Cho ◽  
Takashi Saito ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Photoelectron Spectroscopy ◽  
Porous Surface ◽  
Potential Approach ◽  
X Ray ◽  
In Vitro Biocompatibility ◽  
Adhesion Ability ◽  
Transmission Electron ◽  
Hierarchical Porous

The effects of the nano-titanium hydrides (nano-γ-TiH) phase on the formation of nanoporous Ti oxide layer by the potential approach (hydrogen fluoride (HF) pretreatment and sodium hydroxide (NaOH) anodization) were investigated using scanning electron microscopy, X-ray photoelectron spectroscopy, X-ray diffractometry, and transmission electron microscopy. The nano-γ-TiH phase was formed by the HF pretreatment with various current densities. After the NaOH anodization, the nano-γ-TiH phase was dissolved and transformed into nanoporous rutile-Ti dioxide (R-TiO2). As the Ti underwent HF pretreatment and NaOH anodization, the microstructure on the surface layer was transformed from α-Ti → (α-Ti + nano-γ-TiH) → (α-Ti + R-TiO2). In-vitro biocompatibility also indicated that the Ti with a hierarchical porous (micro and nanoporous) TiO2 surface possessed great potential to enhance cell adhesion ability. Thus, the potential approach can be utilized to fabricate a promising hierarchical porous surface on the Ti implant for promoting biocompatibility.

scholarly journals In vitro biocompatibility of a sandblasted, acid-etched HA composite coating on ultrafine-grained titanium

RSC Advances ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 6124-6130
Author(s):  
Yanxia Chi ◽  
Sipeng An ◽  
Yunpeng Xu ◽  
Mingda Liu ◽  
Jie Zhang
Keyword(s):  
Composite Coating ◽  
Acid Etching ◽  
In Vitro Biocompatibility ◽  
Ultrafine Grained ◽  
Electrophoresis Deposition

A sandblasted, acid-etched hydroxyapatite (SLA-HA) composite coating on ultrafine-grained titanium was synthesized by sandblasting, acid etching and electrophoresis deposition.

Enhanced in vitro biocompatibility of ultrafine-grained biomedical NiTi alloy with microporous surface

2011 ◽  
Vol 257 (21) ◽  
pp. 9086-9093 ◽  
Author(s):  
C.Y. Zheng ◽  
F.L. Nie ◽  
Y.F. Zheng ◽  
Y. Cheng ◽  
S.C. Wei ◽  
...  
Keyword(s):  
Niti Alloy ◽  
In Vitro Biocompatibility ◽  
Ultrafine Grained

scholarly journals Template-assisted, Sol-gel Fabrication of Biocompatible, Hierarchically Porous Hydroxyapatite Scaffolds

Materials ◽  
2019 ◽  
Vol 12 (8) ◽  
pp. 1274 ◽  
Author(s):  
Xingyuan Zhang ◽  
Lirong Zhang ◽  
Yuanwei Li ◽  
Youlu Hua ◽  
Yangde Li ◽  
...  
Keyword(s):  
High Surface ◽  
Sol Gel ◽  
High Surface Area ◽  
Culture Cell ◽  
Porous Structures ◽  
Porous Hydroxyapatite ◽  
Hierarchically Porous ◽  
In Vitro Biocompatibility ◽  
Hierarchical Porous

Hierarchically porous hydroxyapatite (HHA) scaffolds were synthesized by template-assisted sol-gel chemistry. Polyurethane foam and a block copolymer were used as templates for inducing hierarchically porous structures. The HHA scaffolds exhibited open porous structures with large pores of 400–600 µm and nanoscale pores of ~75 nm. In comparison with conventional hydroxyapatite (CHA), HHA scaffolds exhibited significantly higher surface areas and increased protein adsorption for bovine serum albumin and vitronectin. Both the HHA and CHA scaffolds exhibited well in vitro biocompatibility. After 1 day, Saos-2 osteoblast-like cells bound equally well to both HHA and CHA scaffolds, but after 7 days in culture, cell proliferation was significantly greater on the HHA scaffolds (p < 0.01). High surface area and hierarchical porous structure contributed to the selective enhancement of osteoblast proliferation on the HHA scaffolds.

In vitro biocompatibility of an ultrafine grained zirconium

Biomaterials ◽  
2007 ◽  
Vol 28 (30) ◽  
pp. 4343-4354 ◽  
Author(s):  
L SALDANA ◽  
A MENDEZVILAS ◽  
L JIANG ◽  
M MULTIGNER ◽  
J GONZALEZCARRASCO ◽  
...  
Keyword(s):  
In Vitro Biocompatibility ◽  
Ultrafine Grained

In vitro biocompatibility of nanoscale zerovalent iron particles (NZVI) synthesized using tea polyphenols

2010 ◽  
Vol 12 (1) ◽  
pp. 114-122 ◽  
Author(s):  
Mallikarjuna N. Nadagouda ◽  
Alicia B. Castle ◽  
Richard C. Murdock ◽  
Saber M. Hussain ◽  
Rajender S. Varma
Keyword(s):  
Tea Polyphenols ◽  
Zerovalent Iron ◽  
Iron Particles ◽  
Nanoscale Zerovalent Iron ◽  
In Vitro Biocompatibility

scholarly journals Surface Properties and Biocompatibility of Anodized Titanium with a Potential Pretreatment for Biomedical Applications

Metals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1090
Author(s):  
Bai-Hung Huang ◽  
Yi-Jung Lu ◽  
Wen-Chien Lan ◽  
Muhammad Ruslin ◽  
Hung-Yang Lin ◽  
...  
Keyword(s):  
Porous Structure ◽  
Biomedical Applications ◽  
Grazing Incidence ◽  
Acid Pretreatment ◽  
Osteoblast Cells ◽  
In Vitro Biocompatibility ◽  
Porous Ti ◽  
Diphenyltetrazolium Bromide ◽  
Anodized Titanium

The effects of anodized titanium (Ti) with a potential hydrogen fluoride (HF) acid pretreatment through cathodization on the formation of nano-porous Ti dioxide (TiO2) layer were characterized using field-emission scanning electron microscopy, grazing incidence X-ray diffractometer, and contact angle goniometer. The biocompatibility was determined by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) test. Analytical results found that a well-aligned nano-porous structure was formed on the anodized Ti surface with HF pretreatment concentration above 0.5%. Microstructure of the nano-porous Ti dioxide surface generated by anodization with HF pretreatment was composed of anatase and rutile phases, while the anodized Ti sample with HF pretreatment concentration of 0.5% presented excellent hydrophilicity surface. An in-vitro biocompatibility also indicated that osteoblast cells grown on the surface of the anodized Ti sample with HF pretreatment increased with the increase of culture time. The filopodia of osteoblast cells not only adhered flat, but also tightly grabbed the nano-porous structure for promoting cell adhesion and proliferation. Therefore, the anodized Ti with HF pretreatment can form a functionalized surface with great biocompatibility for biomedical applications, particularly for dental implants.

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