scholarly journals Design, synthesis, and biological evaluation of quinazolin-4(3H)-one derivatives co-targeting poly(ADP-ribose) polymerase-1 and bromodomain containing protein 4 for breast cancer therapy

2020 ◽  
Author(s):  
Xiaosa Chang ◽  
Dejuan Sun ◽  
Danfeng Shi ◽  
Guan Wang ◽  
Yanmei Chen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Therapy ◽  
Biological Evaluation ◽  
Breast Cancer Therapy ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation

scholarly journals Design, synthesis, and biological evaluation of new 6,N2-diaryl-1,3,5-triazine-2,4-diamines as anticancer agents selectively targeting triple negative breast cancer cells

RSC Advances ◽  
2020 ◽  
Vol 10 (43) ◽  
pp. 25517-25528
Author(s):  
Ahmad Junaid ◽  
Felicia Phei Lin Lim ◽  
Edward R. T. Tiekink ◽  
Anton V. Dolzhenko
Keyword(s):  
Breast Cancer ◽  
Triple Negative Breast Cancer ◽  
Anticancer Agents ◽  
Breast Cancer Cells ◽  
Triple Negative ◽  
3D Qsar ◽  
Qsar Model ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation

New highly potent and selective 6,N2-diaryl-1,3,5-triazine-2,4-diamines were designed and prepared using the 3D-QSAR model developed earlier.

Design, Synthesis, and Mechanistic Investigations of Bile Acid–Tamoxifen Conjugates for Breast Cancer Therapy

2013 ◽  
Vol 24 (9) ◽  
pp. 1468-1484 ◽  
Author(s):  
Vedagopuram Sreekanth ◽  
Sandhya Bansal ◽  
Rajender K. Motiani ◽  
Somanath Kundu ◽  
Sravan Kumar Muppu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Bile Acid ◽  
Cancer Therapy ◽  
Breast Cancer Therapy ◽  
Design Synthesis ◽  
Mechanistic Investigations

Design, synthesis and biological evaluation of novel FGFR inhibitors bearing an indazole scaffold

2015 ◽  
Vol 13 (28) ◽  
pp. 7643-7654 ◽  
Author(s):  
Jian Liu ◽  
Xia Peng ◽  
Yang Dai ◽  
Wei Zhang ◽  
Sumei Ren ◽  
...  
Keyword(s):  
Growth Factor ◽  
Cancer Therapy ◽  
Fibroblast Growth Factor ◽  
Fibroblast Growth Factor Receptor ◽  
Growth Factor Receptor ◽  
Biological Evaluation ◽  
Fibroblast Growth ◽  
Design Synthesis ◽  
Potential Target ◽  
Synthesis And Biological Evaluation

Fibroblast growth factor receptor (FGFR) is a potential target for cancer therapy.

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