Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells

Baoyuan Zhang; Junfang Lyu; Eun Ju Yang; Yifan Liu; Changjie Wu; Lakhansing Pardeshi; Kaeling Tan; Qiang Chen; Xiaoling Xu; Chu-Xia Deng; Joong Sup Shim

doi:10.1016/j.apsb.2019.08.008

Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells

Acta Pharmaceutica Sinica B ◽

10.1016/j.apsb.2019.08.008 ◽

2020 ◽

Vol 10 (4) ◽

pp. 615-627 ◽

Cited By ~ 4

Author(s):

Baoyuan Zhang ◽

Junfang Lyu ◽

Eun Ju Yang ◽

Yifan Liu ◽

Changjie Wu ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Breast Cancer Cells ◽

Class I ◽

Histone Deacetylase Inhibition ◽

Synthetic Lethal

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Histone deacetylase inhibition and estrogen signalling in human breast cancer cells

Biochemical Pharmacology ◽

10.1016/j.bcp.2004.04.031 ◽

2004 ◽

Vol 68 (6) ◽

pp. 1239-1246 ◽

Cited By ~ 41

Author(s):

Raphaël Margueron ◽

Vanessa Duong ◽

Audrey Castet ◽

Vincent Cavaillès

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Histone Deacetylase Inhibition

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Abstract P6-14-01: A class I histone deacetylase inhibitor, entinostat, enhances lapatinib efficacy in both HER2-overexpressing inflammatory and non-inflammatory breast cancer cells through FOXO3-mediated Bim1 expression

10.1158/1538-7445.sabcs14-p6-14-01 ◽

2015 ◽

Author(s):

Jangsoon Lee ◽

Chandra Bartholomeusz ◽

Gabriel N Hortobagyi ◽

Peter Ordentlich ◽

Naoto T Ueno

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Inflammatory Breast Cancer ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Cells ◽

Class I ◽

Deacetylase Inhibitor

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295 POSTER Histone deacetylase inhibition modulates estrogen receptor expression at multiple levels in breast cancer cells

European Journal of Cancer Supplements ◽

10.1016/s1359-6349(06)70300-7 ◽

2006 ◽

Vol 4 (12) ◽

pp. 93

Author(s):

D. Russell ◽

L. deGraffenried ◽

J. Freeman ◽

J. Silva ◽

W. Friedrichs ◽

...

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Cancer Cells ◽

Histone Deacetylase ◽

Breast Cancer Cells ◽

Receptor Expression ◽

Estrogen Receptor Expression ◽

Histone Deacetylase Inhibition ◽

Multiple Levels

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A class I histone deacetylase inhibitor, entinostat, enhances lapatinib efficacy in HER2-overexpressing breast cancer cells through FOXO3-mediated Bim1 expression

Breast Cancer Research and Treatment ◽

10.1007/s10549-014-3014-7 ◽

2014 ◽

Vol 146 (2) ◽

pp. 259-272 ◽

Cited By ~ 27

Author(s):

Jangsoon Lee ◽

Chandra Bartholomeusz ◽

Oula Mansour ◽

Juliane Humphries ◽

Gabriel N. Hortobagyi ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Cells ◽

Class I ◽

Deacetylase Inhibitor

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Cytotoxic Effects of Jay Amin Hydroxamic Acid (JAHA), a Ferrocene-Based Class I Histone Deacetylase Inhibitor, on Triple-Negative MDA-MB231 Breast Cancer Cells

Chemical Research in Toxicology ◽

10.1021/tx300376h ◽

2012 ◽

Vol 25 (11) ◽

pp. 2608-2616 ◽

Cited By ~ 43

Author(s):

Mariangela Librizzi ◽

Alessandra Longo ◽

Roberto Chiarelli ◽

Jahanghir Amin ◽

John Spencer ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Hydroxamic Acid ◽

Breast Cancer Cells ◽

Triple Negative ◽

Class I ◽

Cytotoxic Effects ◽

Deacetylase Inhibitor

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Downregulation of the Ca 2+ ‐activated K + channel K C a 3.1 by histone deacetylase inhibition in human breast cancer cells

Pharmacology Research & Perspectives ◽

10.1002/prp2.228 ◽

2016 ◽

Vol 4 (2) ◽

Cited By ~ 8

Author(s):

Susumu Ohya ◽

Saki Kanatsuka ◽

Noriyuki Hatano ◽

Hiroaki Kito ◽

Azusa Matsui ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

K Channel ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Histone Deacetylase Inhibition

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Histone deacetylase inhibitors sensitize 5‑fluorouracil‑resistant MDA‑MB‑468 breast cancer cells to 5‑fluorouracil

Oncology Letters ◽

10.3892/ol.2018.9388 ◽

2018 ◽

Cited By ~ 1

Author(s):

Tetsuya Minegaki ◽

Ai Suzuki ◽

Misato Mori ◽

Shiori Tsuji ◽

Satoshi Yamamoto ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Breast Cancer Cells ◽

Histone Deacetylase Inhibitors

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Synthetic Lethal Interactions between EGFR and PARP Inhibition in Human Triple Negative Breast Cancer Cells

PLoS ONE ◽

10.1371/journal.pone.0046614 ◽

2012 ◽

Vol 7 (10) ◽

pp. e46614 ◽

Cited By ~ 64

Author(s):

Somaira Nowsheen ◽

Tiffiny Cooper ◽

Jennifer A. Stanley ◽

Eddy S. Yang

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Triple Negative Breast Cancer ◽

Breast Cancer Cells ◽

Triple Negative ◽

Parp Inhibition ◽

Synthetic Lethal ◽

Synthetic Lethal Interactions

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Histone deacetylase 4 mediates SMAD family member 4 deacetylation and induces 5-fluorouracil resistance in breast cancer cells

Oncology Reports ◽

10.3892/or.2013.2578 ◽

2013 ◽

Vol 30 (3) ◽

pp. 1293-1300 ◽

Cited By ~ 18

Author(s):

SEONG-LAN YU ◽

DONG CHUL LEE ◽

JI WOONG SON ◽

CHANG GYO PARK ◽

HOI YOUNG LEE ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Family Member ◽

Histone Deacetylase ◽

Breast Cancer Cells ◽

Histone Deacetylase 4

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Histone deacetylase 8 triggers the migration of triple negative breast cancer cells via regulation of YAP signals

European Journal of Pharmacology ◽

10.1016/j.ejphar.2018.12.030 ◽

2019 ◽

Vol 845 ◽

pp. 16-23 ◽

Cited By ~ 10

Author(s):

Panpan An ◽

Jiexin Li ◽

Linlin Lu ◽

Yingmin Wu ◽

Yuyi Ling ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Triple Negative Breast Cancer ◽

Breast Cancer Cells ◽

Triple Negative ◽

Histone Deacetylase 8

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