Short-Term Improvement in Physical Activity and Body Composition After Supervised Exercise Training Program in Idiopathic Pulmonary Fibrosis

2016 ◽  
Vol 97 (5) ◽  
pp. 788-797 ◽  
Author(s):  
Baruch Vainshelboim ◽  
Benjamin Daniel Fox ◽  
Mordechai Reuven Kramer ◽  
Shimon Izhakian ◽  
Evgeni Gershman ◽  
...  
2021 ◽  
Author(s):  
Victoria Motz ◽  
Alison Faust ◽  
Jessica Dahmus ◽  
Benjamin Stern ◽  
Christopher Soriano ◽  
...  

BACKGROUND Most patients with nonalcoholic fatty liver disease (NAFLD) are physically inactive despite the well-known benefits of physical activity. Telehealth offers promise as a novel way to deliver an exercise training program and increase physical activity. However, the feasibility, safety and efficacy of telehealth-based exercise programs is unknown in patients with NAFLD. OBJECTIVE To determine the feasibility of a directly supervised exercise training program delivered to patients with nonalcoholic steatohepatitis (NASH), the progressive form of NAFLD, exclusively with telehealth. METHODS In response to COVID-19 research restrictions, we adapted an existing clinical trial and delivered 20-weeks of moderate-intensity aerobic training five days a week under real-time direct supervision using an audio-visual telehealth platform. Aerobic training was completed by walking outdoors or using a home treadmill. Fitness activity trackers with heart rate monitors ensured exercise was completed at the prescribed intensity with real-time feedback from an Exercise Physiologist. RESULTS Three patients with biopsy-proven NASH were enrolled with mean age of 52 +/- 14 years. Mean body mass index was 31.9 +/- 5.1 kg/m2. All subjects had metabolic syndrome. All subjects completed >80% of exercise sessions (mean 84 +/- 3%) and no adverse events occurred. Body weight (-5.1 +/- 3.7%), body fat (-4.4 +/- 2.3%) and waist circumference (-1.3 +/- 1.6 inches) all improved with exercise. Relative reduction in magnetic resonance imaging proton density fat fraction (MRI-PDFF) was 35.1 +/- 8.8%. Reductions in hemoglobin A1c -0.5 +/- 0.2% and HOMA-IR -4.0 +/- 1.2 were observed. Peak oxygen consumption (VO2 peak) improved by +9.9 +/- 6.6 mL/kg/min. CONCLUSIONS This proof of concept study found supervised exercise training delivered via telehealth is feasible and safe in patients with NASH. Telehealth-based exercise training also appears to be highly efficacious in patients with NASH but this will need to be confirmed by future large-scale trials. CLINICALTRIAL NCT03518294


Lung ◽  
2015 ◽  
Vol 193 (3) ◽  
pp. 345-354 ◽  
Author(s):  
Baruch Vainshelboim ◽  
Jose Oliveira ◽  
Benjamin Daniel Fox ◽  
Yafit Soreck ◽  
Oren Fruchter ◽  
...  

Author(s):  
Jaume Bordas Martinez ◽  
Jose Manuel Palma Lopez ◽  
Mariagna Sampere Aymerich ◽  
Anna Bachs Salvado ◽  
Lurdes Planas Cerezales ◽  
...  

2006 ◽  
Vol 38 (Supplement) ◽  
pp. S333
Author(s):  
Elaine M. Concklin ◽  
Michelle A. Provost-Craig ◽  
Elizabeth Orsega-Smaith ◽  
Nancy Getchell ◽  
William Farquhar

2016 ◽  
Vol 59 ◽  
pp. e55 ◽  
Author(s):  
Katia Reichhart ◽  
Mélissa Evesque ◽  
Marion M.C. Cavana ◽  
Pauline Muszynski ◽  
Marie-Madeleine Leclercq ◽  
...  

2017 ◽  
Vol 14 (5) ◽  
pp. 353-359 ◽  
Author(s):  
Cadeyrn J. Gaskin ◽  
Melinda Craike ◽  
Mohammadreza Mohebbi ◽  
Kerry S. Courneya ◽  
Patricia M. Livingston

Background:The ENGAGE (efficacy of a referral and physical activity program for survivors of prostate cancer) study established that a clinician referral and 12-week exercise training program increased vigorous physical activity at 12 weeks among men with prostate cancer. Here, we report the 6- and 12-month outcomes.Methods:In this multicenter cluster randomized controlled trial, we compared a clinician referral and exercise training program to usual care. Discounted gym membership was offered to men in the intervention condition on completion of the 12-week exercise program. Self-reported physical activity at 6 and 12 months was the primary outcome. Quality of life, anxiety, and depressive symptoms were secondary outcomes.Results:A total of 147 men meeting eligibility criteria agreed to participate (54 intervention, 93 control). A positive interaction effect for vigorous physical activity was observed at 6 months, but not 12 months. No significant effects for the secondary outcomes were found.Conclusions:A clinician referral and community-based supervised and unsupervised exercise training program, along with discounted gym membership, had a positive short-term effect on vigorous physical activity levels, but did not improve quality of life, in men with prostate cancer.


2011 ◽  
Vol 43 (9) ◽  
pp. 1744-1751 ◽  
Author(s):  
VIKRAM V. RANGAN ◽  
LESLIE H. WILLIS ◽  
CRIS A. SLENTZ ◽  
LORI A. BATEMAN ◽  
A. TAMLYN SHIELDS ◽  
...  

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