Immunogenicity of Malaria Vaccine Candidate - Plasmodium Falciparum Merozoite Surface Protein 5 (PfMSP5) Expressed in Bacillus subtilis

APCBEE Procedia ◽

10.1016/j.apcbee.2014.01.021 ◽

2014 ◽

Vol 9 ◽

pp. 113-119

Author(s):

Chittibabu Gottimukkala ◽

Charles Ma ◽

Hans J. Netter ◽

Santosh B. Noronha ◽

Ross L. Coppel

Keyword(s):

Plasmodium Falciparum ◽

Bacillus Subtilis ◽

Malaria Vaccine ◽

Vaccine Candidate ◽

Surface Protein ◽

Merozoite Surface Protein ◽

Falciparum Merozoite ◽

Malaria Vaccine Candidate

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Antibodies to Plasmodium falciparum merozoite surface protein-1p19 malaria vaccine candidate induce antibody-dependent respiratory burst in human neutrophils

Malaria Journal ◽

10.1186/s12936-015-0935-5 ◽

2015 ◽

Vol 14 (1) ◽

Cited By ~ 12

Author(s):

Charlotte Joos ◽

Marie-Louise Varela ◽

Babacar Mbengue ◽

Annick Mansourou ◽

Laurence Marrama ◽

...

Keyword(s):

Plasmodium Falciparum ◽

Respiratory Burst ◽

Malaria Vaccine ◽

Vaccine Candidate ◽

Surface Protein ◽

Merozoite Surface Protein ◽

Human Neutrophils ◽

Falciparum Merozoite ◽

Malaria Vaccine Candidate ◽

Induce Antibody

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Genetic Diversity of the Malaria Vaccine Candidate Plasmodium falciparum Merozoite Surface Protein-3 in a Hypoendemic Transmission Environment

American Journal of Tropical Medicine and Hygiene ◽

10.4269/ajtmh.2009.80.479 ◽

2009 ◽

Vol 80 (3) ◽

pp. 479-486 ◽

Cited By ~ 7

Author(s):

Stephen J. Jordan ◽

Julian C. Rayner ◽

OraLee H. Branch ◽

Jean Carlos Castro ◽

Robert A. Oster

Keyword(s):

Genetic Diversity ◽

Plasmodium Falciparum ◽

Malaria Vaccine ◽

Vaccine Candidate ◽

Surface Protein ◽

Merozoite Surface Protein ◽

Falciparum Merozoite ◽

Malaria Vaccine Candidate

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Expression of Plasmodium falciparum C-terminal region of merozoite surface protein (PfMSP119), a potential malaria vaccine candidate, in tobacco

Plant Science ◽

10.1016/s0168-9452(01)00555-6 ◽

2002 ◽

Vol 162 (3) ◽

pp. 335-343 ◽

Cited By ~ 28

Author(s):

Sagar Ghosh ◽

Pawan Malhotra ◽

P.V Lalitha ◽

Sipra Guha-Mukherjee ◽

V.S Chauhan

Keyword(s):

Plasmodium Falciparum ◽

Malaria Vaccine ◽

Vaccine Candidate ◽

Surface Protein ◽

Merozoite Surface Protein ◽

Terminal Region ◽

Malaria Vaccine Candidate

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Geographical patterns of allelic diversity in the Plasmodium falciparum malaria-vaccine candidate, merozoite surface protein-2

Annals of Tropical Medicine and Parasitology ◽

10.1080/00034980120045833 ◽

2001 ◽

Vol 95 (2) ◽

pp. 117-132 ◽

Cited By ~ 23

Author(s):

E. H. E. Hoffmann, L. A. da Silveira,

Keyword(s):

Plasmodium Falciparum ◽

Falciparum Malaria ◽

Malaria Vaccine ◽

Vaccine Candidate ◽

Allelic Diversity ◽

Surface Protein ◽

Plasmodium Falciparum Malaria ◽

Merozoite Surface Protein ◽

Geographical Patterns ◽

Malaria Vaccine Candidate

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Sequence diversity and evolution of the malaria vaccine candidate merozoite surface protein-1 (MSP-1) of Plasmodium falciparum

Gene ◽

10.1016/s0378-1119(02)01180-0 ◽

2003 ◽

Vol 304 ◽

pp. 65-75 ◽

Cited By ~ 57

Author(s):

M Ferreira

Keyword(s):

Plasmodium Falciparum ◽

Malaria Vaccine ◽

Vaccine Candidate ◽

Surface Protein ◽

Merozoite Surface Protein ◽

Sequence Diversity ◽

Merozoite Surface Protein 1 ◽

Malaria Vaccine Candidate

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Origins of sequence diversity in the malaria vaccine candidate merozoite surface protein-2 (MSP-2) in Amazonian isolates of Plasmodium falciparum

Gene ◽

10.1016/j.gene.2006.03.011 ◽

2006 ◽

Vol 376 (2) ◽

pp. 224-230 ◽

Cited By ~ 12

Author(s):

Erika H.E. Hoffmann ◽

Rosely S. Malafronte ◽

Sandra L. Moraes-Ávila ◽

Ana Lúcia Osakabe ◽

Gerhard Wunderlich ◽

...

Keyword(s):

Plasmodium Falciparum ◽

Malaria Vaccine ◽

Vaccine Candidate ◽

Surface Protein ◽

Merozoite Surface Protein ◽

Sequence Diversity ◽

Malaria Vaccine Candidate

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Crystal Structure of a Fab Complex Formed with PfMSP1-19, the C-terminal Fragment of Merozoite Surface Protein 1 from Plasmodium falciparum: A Malaria Vaccine Candidate

Journal of Molecular Biology ◽

10.1016/s0022-2836(03)00376-0 ◽

2003 ◽

Vol 328 (5) ◽

pp. 1091-1103 ◽

Cited By ~ 57

Author(s):

J.C Pizarro ◽

V Chitarra ◽

D Verger ◽

I Holm ◽

S Pêtres ◽

...

Keyword(s):

Crystal Structure ◽

Plasmodium Falciparum ◽

Malaria Vaccine ◽

Vaccine Candidate ◽

Surface Protein ◽

Merozoite Surface Protein ◽

Merozoite Surface Protein 1 ◽

Terminal Fragment ◽

Malaria Vaccine Candidate

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Plasmodium falciparum: Worldwide sequence diversity and evolution of the malaria vaccine candidate merozoite surface protein-2 (MSP-2)

Experimental Parasitology ◽

10.1016/j.exppara.2006.05.003 ◽

2007 ◽

Vol 115 (1) ◽

pp. 32-40 ◽

Cited By ~ 35

Author(s):

Marcelo U. Ferreira ◽

Daniel L. Hartl

Keyword(s):

Plasmodium Falciparum ◽

Malaria Vaccine ◽

Vaccine Candidate ◽

Surface Protein ◽

Merozoite Surface Protein ◽

Sequence Diversity ◽

Malaria Vaccine Candidate

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Soluble and glyco-lipid modified baculovirus Plasmodium falciparum C-terminal merozoite surface protein 1, two forms of a leading malaria vaccine candidate

Vaccine ◽

10.1016/j.vaccine.2006.04.069 ◽

2006 ◽

Vol 24 (33-34) ◽

pp. 5997-6008 ◽

Cited By ~ 24

Author(s):

S BONNET ◽

S PETRES ◽

I HOLM ◽

T FONTAINE ◽

S ROSARIO ◽

...

Keyword(s):

Plasmodium Falciparum ◽

Malaria Vaccine ◽

Vaccine Candidate ◽

Surface Protein ◽

Merozoite Surface Protein ◽

Merozoite Surface Protein 1 ◽

Malaria Vaccine Candidate

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Immunoglobulin G3 Antibodies Specific for the 19-Kilodalton Carboxyl-Terminal Fragment of Plasmodium yoelii Merozoite Surface Protein 1 Transfer Protection to Mice Deficient in Fc-γRI Receptors

Infection and Immunity ◽

10.1128/iai.68.5.3019-3022.2000 ◽

2000 ◽

Vol 68 (5) ◽

pp. 3019-3022 ◽

Cited By ~ 20

Author(s):

Peter Vukovic ◽

P. Mark Hogarth ◽

Nadine Barnes ◽

David C. Kaslow ◽

Michael F. Good

Keyword(s):

Malaria Vaccine ◽

Vaccine Candidate ◽

Surface Protein ◽

Merozoite Surface Protein ◽

Plasmodium Yoelii ◽

Merozoite Surface Protein 1 ◽

Specific Immunoglobulin ◽

Malaria Vaccine Candidate ◽

Main Action ◽

Carboxyl Terminal

ABSTRACT Merozoite surface protein 1 (MSP-119) is a leading malaria vaccine candidate. Specific antibodies contribute to immunity; binding to macrophages is believed to represent the main action of malaria antibodies. We show that an MSP-119-specific immunoglobulin G3 (IgG3) monoclonal antibody can passively transfer protection to mice deficient in the α chain of Fc-γRI whose macrophages cannot bind IgG3.

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