Intra-prostatic injection of botulinum toxin type A in treatment of dogs with spontaneous benign prostatic hyperplasia

2012 ◽  
Vol 133 (3-4) ◽  
pp. 224-228 ◽  
Author(s):  
Giuliano Queiroz Mostachio ◽  
Maricy Apparício ◽  
Tathiana Ferguson Motheo ◽  
Aracélle Elisane Alves ◽  
Wilter Ricardo Russiano Vicente
Keyword(s):  
Botulinum Toxin ◽  
Benign Prostatic Hyperplasia ◽  
Botulinum Toxin Type A ◽  
Type A ◽  
Botulinum Toxin Type ◽  
Prostatic Hyperplasia

Botulinum toxin type A improves benign prostatic hyperplasia symptoms in patients with small prostates

Urology ◽  
2005 ◽  
Vol 66 (4) ◽  
pp. 775-779 ◽  
Author(s):  
Yao-Chi Chuang ◽  
Po-Hui Chiang ◽  
Chao-Cheng Huang ◽  
Naoki Yoshimura ◽  
Michael B. Chancellor
Keyword(s):  
Botulinum Toxin ◽  
Benign Prostatic Hyperplasia ◽  
Botulinum Toxin Type A ◽  
Type A ◽  
Botulinum Toxin Type ◽  
Prostatic Hyperplasia

Intraprostatic botulinum toxin type A injection for the treatment of benign prostatic hyperplasia: Initial experience with Dysport™

2010 ◽  
Vol 44 (3) ◽  
pp. 151-157 ◽  
Author(s):  
Mohammadreza Nikoobakht ◽  
Azar Daneshpajooh ◽  
Hamed Ahmadi ◽  
Farshad Namdari ◽  
Maedeh Rezaeidanesh ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Benign Prostatic Hyperplasia ◽  
Botulinum Toxin Type A ◽  
Type A ◽  
Botulinum Toxin Type ◽  
Prostatic Hyperplasia ◽  
Initial Experience

Treatment of Benign Prostatic Hyperplasia by Ultrasound-Guided Botulinum Toxin Type A Injection

2015 ◽  
Vol 73 (2) ◽  
pp. 357-359 ◽  
Author(s):  
Xu-Dong Ding ◽  
Huan-Xian Chen ◽  
Hong-Qiong Xiao ◽  
Wei Wang ◽  
Zhi-Gang Ding ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Benign Prostatic Hyperplasia ◽  
Botulinum Toxin Type A ◽  
Type A ◽  
Botulinum Toxin Type ◽  
Prostatic Hyperplasia ◽  
Ultrasound Guided

scholarly journals Semen parameters and seminal plasma protein and biochemical profiles of dogs with benign prostatic hyperplasia after botulinum toxin type A intraprostatic injection

2014 ◽  
Vol 44 (6) ◽  
pp. 1113-1118 ◽  
Author(s):  
Tathiana Ferguson Motheo ◽  
Aracélle Elisane Alves ◽  
Giuliano Queiroz Mostachio ◽  
Maricy Apparício ◽  
Alexandre Pinto Ribeiro ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Benign Prostatic Hyperplasia ◽  
Plasma Protein ◽  
Seminal Plasma ◽  
Botulinum Toxin Type A ◽  
Botulinum Toxin Type ◽  
Prostatic Hyperplasia ◽  
Semen Parameters ◽  
Protein Profiles ◽  
Sds Page

This study aimed to determine the effects of different concentrations of botulinum toxin type A (BT-A) on semen parameters, and seminal plasma biochemical and protein profiles of dogs with benign prostatic hyperplasia (BPH). Eighteen sexually intact male dogs with BPH were randomly divided in three groups, and received an intraprostatic injection of saline solution (control group - CG), 250UI (GI) or 500UI (GII) of BT-A under transabdominal ultrasound guidance. Semen was collected at baseline, 2, 4 and 8 weeks after treatment. Semen parameters were determined and seminal plasma pH, total protein (TP), total chlorides (TC), calcium (Ca), potassium (K), and sodium (Na) concentrations were assessed. One-dimensional sodium dodecyl sulfatepolyacrilamide gel eletrophoresis (SDS- PAGE) was performed to determine seminal plasma protein profile. Sperm parameters and seminal plasma pH, TP, TC, Ca and K mean values did not change significantly at any time point and among treated groups (P>0.05). The SDS-PAGE analysis of the pooled fractions identified 31 protein bands with molecular weights ranging from 3.9 to 106.2kDA in all treatment groups during the entire evaluation period. Regardless the used dose, intraprostatic BT-A injection do not alter semen parameters and seminal plasma biochemical and protein profiles of dogs with BPH.

Sign in / Sign up

Export Citation Format

Share Document