scholarly journals Non-islet-cell tumour hypoglycaemia (NICTH): About a series of 6 cases

2019 ◽  
Vol 80 (1) ◽  
pp. 21-25 ◽  
Author(s):  
Arnaud Jannin ◽  
Stéphanie Espiard ◽  
Kanza Benomar ◽  
Christine Do Cao ◽  
Bénédicte Mycinski ◽  
...  
Keyword(s):  
Islet Cell ◽  
Cell Tumour ◽  
Islet Cell Tumour

Non islet cell tumour hypoglycaemia: management strategies for a rare and challenging condition

2014 ◽  
Author(s):  
Dhanya Kalathil ◽  
Simon Roughneen ◽  
Momin Shah ◽  
Ali Akram ◽  
Reza Zaidi ◽  
...  
Keyword(s):  
Islet Cell ◽  
Management Strategies ◽  
Cell Tumour ◽  
Islet Cell Tumour

scholarly journals Streptozotocin treatment of malignant islet cell tumour.

BMJ ◽  
1970 ◽  
Vol 3 (5722) ◽  
pp. 562-563 ◽  
Author(s):  
N N Stanley ◽  
V Marks ◽  
L Kreel ◽  
N McIntyre
Keyword(s):  
Islet Cell ◽  
Cell Tumour ◽  
Islet Cell Tumour

scholarly journals Non-islet-cell tumour hypoglycaemia in a cat with hepatocellular carcinoma

2019 ◽  
Vol 5 (1) ◽  
pp. 205511691985612
Author(s):  
Alexandra Guillen ◽  
Lorenzo Ressel ◽  
Riccardo Finotello ◽  
Alexander J German ◽  
Alistair Freeman ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Islet Cell ◽  
Abdominal Mass ◽  
Reference Interval ◽  
Serum Glucose ◽  
Cell Tumour ◽  
Surgical Removal ◽  
Islet Cell Tumour ◽  
Insulin Growth Factor ◽  
Well Differentiated

Case summary An 11-year-old male neutered domestic shorthair cat presented with behavioural changes. Physical examination revealed bradycardia and a cranial abdominal mass. The cat was persistently hypoglycaemic (1.2 mmol/l; reference interval [RI] 3.5–5.5 mmol/l) with decreased fructosamine concentration suggesting chronic hypoglycaemia, and decreased insulin concentration excluding insulinoma. Alanine aminotransferase activity was markedly increased (1219.31 U/l; RI 15–60 U/l). On staging CT a large, multilobulated hepatic mass was identified, with no evidence of metastatic disease. After surgical removal serum glucose concentration and heart rate quickly returned to within the RIs. Histopathology was consistent with a solid-to-trabecular, well-differentiated, hepatocellular carcinoma. There was no recurrence of signs or mass during 8 months of follow-up, and the cat was still alive 20 months after surgery. Relevance and novel information Non-islet-cell tumour hypoglycaemia (NICTH) is a rare but life-threatening paraneoplastic syndrome. In humans, hepatocellular carcinoma is the most common epithelial tumour causing NICTH, but these are uncommon in cats, and associated paraneoplastic hypoglycaemia has not been reported. Possible mechanisms include aberrant secretion of big insulin growth factor 2; however, this could not be confirmed. NICTH should be considered in the differential diagnosis of cats with persistent hypoglycaemia.

Non-islet cell tumour hypoglycaemia

1999 ◽  
Vol 51 (2) ◽  
pp. 147-147 ◽  
Author(s):  
J. D. Teale
Keyword(s):  
Islet Cell ◽  
Cell Tumour ◽  
Islet Cell Tumour

ISLET-CELL TUMOUR OF PANCREAS REPORT OF A CASE

The Lancet ◽  
1952 ◽  
Vol 259 (6702) ◽  
pp. 289-293 ◽  
Author(s):  
A.N. Smith ◽  
J.B. Cochran
Keyword(s):  
Islet Cell ◽  
Cell Tumour ◽  
Islet Cell Tumour
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