Hyperprolactinemia in post-menopausal women: A case report

2015 ◽  
Vol 76 (4) ◽  
pp. 389
Author(s):  
I. Barka ◽  
S. Ouerdeni ◽  
Y. Hasni ◽  
I. Slim ◽  
A. Maaroufi ◽  
...  
Author(s):  
Tara Burleigh ◽  
Khandalavala Birgit

Objectives: This is the first case report of iatrogenic Takotsubo syndrome (TS) due to a combination of lisdexamfetamine and phentermine. Background: TS is characterized by transient acute ballooning of the left ventricular wall. Typically, it occurs in extremely stressed post-menopausal women, however a few iatrogenic causes have been described recently. Results: A 55-year old woman prescribed lisdexamfetamine and phentermine, presented with acute substernal chest pain. Acute coronary syndrome was excluded. The echocardiogram was diagnostic of TS, and she recovered spontaneously, with supportive care. Conclusion: Caution with the use of sympathomimetic medications in post-menopausal women appears warranted.


2015 ◽  
Vol 76 (2) ◽  
Author(s):  
Mariantonietta D’Agostino ◽  
Francesco Giallauria ◽  
Caterina Montuori ◽  
Francesca Farina ◽  
Luigi Maresca ◽  
...  

Introduction. Takotsubo syndrome is a reversibile cardiomyopathy that often occurs during an emotional stress and is more frequent in post-menopausal women. Case presentation. We describe a clinic case of a 42 years old woman, admitted to our emergency unit because of a thoracic pain. The ECG showed ST-T elevation in V1- V4, the echocardiography revealed akinesia of apical segment of left ventricle. Coronary arteries were free from significant stenosis and ventriculography showed akinesia of apical segment of left ventricle. In the following days, ECG evolved toward a normalization of ST-T segment with appearance of negative T wave in V2-V6, and also the echocardiography showed a normalized LV wall motion. The patient was discharged and ECG and echocardiography were normal at two months follow up. Conclusion. In this case report, a young woman during puerperium presented with a Takotsubo syndrome. We speculate that the high Prolactin level and her emotional state contributed to the clinical manifestation of the syndrome.


2019 ◽  
Vol 12 (3) ◽  
pp. 807-813
Author(s):  
Joseph W. Clyde ◽  
Alan W. Katz

Adenocarcinoma ex-goblet carcinoid (ADA ex-GCC) is a rare and aggressive subtype of goblet cell carcinoid, a distinct tumor of the appendix characterized by both neuroendocrine and glandular differentiation. Patients often present with chronic abdominal pain or symptoms of acute appendicitis. Right hemicolectomy is the primary mode of treatment, and prophylactic salpingo-oophorectomy and hysterectomy is recommended in post-menopausal women due to the tumor’s propensity of transcoelemic spread, especially to the ovaries. In this case report, we describe a patient with ADA ex-GCC who was found to have oligometastic disease in the pelvis and treated with hypofractionated stereotactic body radiation therapy (HSRT). She initially underwent a right hemicolectomy followed by adjuvant capecitabine four years prior when her tumor was incidentally discovered on colonoscopy. She subsequently had a salpingo-oophorectomy for gynecologic tract metastatic disease and declined further chemotherapy. The patient was again discovered to have oligometastatic disease in the right pelvis adjacent to the rectum on a Gallium-68 dotatate PET/MRI, and was subsequently treated with HSRT to 39 Gy in 6.5 Gy daily fractions. The patient tolerated her radiation course without notable radiation-related toxicity, and she remains without disease progression nine months later.


Cases Journal ◽  
2008 ◽  
Vol 1 (1) ◽  
Author(s):  
Hooman Soleymani majd ◽  
Sean Watermeyer ◽  
Lamiese Ismail

1976 ◽  
Vol 35 (02) ◽  
pp. 403-414 ◽  
Author(s):  
Terence Davies ◽  
Gillian Fieldhouse ◽  
George P. McNicol

SummaryThe effects on the haemostatic mechanism of oestrogen therapy, given to prevent bone loss in post-menopausal women, have been investigated. Oestriol succinate was given orally to 10 women at a level of 2 mg/day for 1 month and for a further 3 months with incremental increase of 2 mg each month. 6 of the 10 women were subsequently treated with 25 μg/day orally of ethinyl oestradiol. Oestriol succinate therapy resulted in a small increase in the level of factor VII, a decrease in factor VIII concentration and increased sensitivity of platelets to aggregating agents. Ethinyl oestradiol treatment resulted in much more widespread changes with marked increases in coagulation factors VII, VIII, IX and X, decreased levels of antithrombin and dramatic increases in circulating plasminogen levels and euglobulin lysis activity. The data suggested that the nature of oestrogens employed therapeutically is important in determining the qualitative and quantitative effect of oestrogen therapy on components of the haemostatic mechanism.


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