Radioiodine therapy in benign thyroid disorders. Evaluation of French nuclear medicine practices

2014 ◽  
Vol 75 (4) ◽  
pp. 241-246 ◽  
Author(s):  
Delphine Bernard ◽  
Marie Dominique Desruet ◽  
Marianne Wolf ◽  
Julie Roux ◽  
Camille Boin ◽  
...  
Keyword(s):  
Nuclear Medicine ◽  
Radioiodine Therapy ◽  
Thyroid Disorders ◽  
Benign Thyroid Disorders ◽  
Benign Thyroid

Radioiodine therapy of benign thyroid disorders: what are the effective thyroidal half-life and uptake of 131I?

2010 ◽  
Vol 31 (3) ◽  
pp. 201-205 ◽  
Author(s):  
Carsten Kobe ◽  
Wolfgang Eschner ◽  
Markus Wild ◽  
Ilka Rahlff ◽  
Ferdinand Sudbrock ◽  
...  
Keyword(s):  
Half Life ◽  
Radioiodine Therapy ◽  
Thyroid Disorders ◽  
Benign Thyroid Disorders ◽  
Benign Thyroid

Radioiodine therapy of benign thyroid-disorders

2017 ◽  
Vol 56 (05) ◽  
pp. 171-176
Author(s):  
Tobias Hartmann ◽  
Werner Vach ◽  
Lars Frings ◽  
Michael Mix ◽  
Philipp Tobias Meyer ◽  
...  
Keyword(s):  
Radioiodine Therapy ◽  
Influence Factors ◽  
Target Volume ◽  
Thyroid Disorders ◽  
Metabolic State ◽  
Patient Age ◽  
Patient Âgé ◽  
Benign Thyroid Disorders ◽  
Nonparametric Correlation ◽  
Benign Thyroid

SummaryAim: In radioiodine therapy (RIT) of benign thyroid-disorders empirical half-lives (HLemp) may be used to calculate therapeutic dose. In this study the effective half-life (HLf as well as potential influence factors were retrospectively determined in order to better estimate HLemp.Methods: Data from patients undergoing RIT from 01/09 to 04/14 were analysed (empirically estimated HLeff stratified by metabolic state and diagnosis). Inclusion criteria were: Benign thyroid-disorders, singular capsule administration and ≥ 6 dosimetry time-points (i. e. > 72 h inpatient stay). The effects of metabolic state, previous thy- reostatic medication and sex on HLeff were assessed by non-parametric ANOVA. The effects of target-volume and patient-age were assessed by regression analysis and nonparametric correlation (Spearman).Results: Data of 1,498 patients were analyzed: Graves’ Disease (GD), n = 286; multinodular goiter/disseminated autonomy (AMG/DA), n = 751; autonomous thyroid nodules (ATN), n = 421; euthyroid goiter (EG), n = 40. Mean HLeff (days ± SD) was 5.4 ± 1.5 in GD, 6.6 ± 1.2 in AMG/DA, 5.5 ± 1.6 in ATN and 6.9 ± 0.7 in EG. HLeff differed by metabolic state in GD, AMG/DA, and ATN, whereas neither thyreos- tatic medication nor sex were relevant. Moreover, target-volume (all diagnoses) and age (ATN and GD only) were associated with HLeft although the effect was small (R2 < 3.8%).Conclusion: When using standard HLeff for RIT, diagnosis and metabolic state should be considered for dose-calculations in RIT. Despite partial significance, the effects of target-volume and patient-age are small and a correction of HLeff, for these factors doesn’t appear to be necessary in a routine setting.

scholarly journals The role of nuclear medicine in the clinical management of benign thyroid disorders. Part 1. Hyperthyroidism

2020 ◽  
pp. jnumed.120.243170
Author(s):  
Giuliano Mariani ◽  
Massimo Tonacchera ◽  
Mariano Grosso ◽  
Francesca Orsolini ◽  
Paolo Vitti ◽  
...  
Keyword(s):  
Nuclear Medicine ◽  
Clinical Management ◽  
Thyroid Disorders ◽  
Benign Thyroid Disorders ◽  
Benign Thyroid

scholarly journals Nationwide trends in surgery and radioiodine treatment for benign thyroid disease during iodization of salt

2010 ◽  
Vol 162 (4) ◽  
pp. 755-762 ◽  
Author(s):  
Charlotte Cerqueira ◽  
Nils Knudsen ◽  
Lars Ovesen ◽  
Peter Laurberg ◽  
Hans Perrild ◽  
...  
Keyword(s):  
Rate Ratio ◽  
Radioiodine Therapy ◽  
Combined Treatment ◽  
Iodine Intake ◽  
Utilization Rate ◽  
Temporary Increase ◽  
Thyroid Disorders ◽  
Treatment Rate ◽  
Benign Thyroid Disorders ◽  
Benign Thyroid

ObjectiveIodization of salt was introduced in Denmark in 1998 because of mild-to-moderate iodine deficiency (ID). The aim of this study was to analyze the utilization rate of surgery and radioiodine therapy for benign thyroid disorders before and after the introduction of iodization, and to study a possible association between the changes and the raised iodine intake.DesignA nationwide register study.MethodsInformation on operations and radioiodine treatments for benign thyroid disorders was extracted from nationwide registers in the years 1990 to 2007. Treatment rates are presented for surgery and for radioiodine separately, and as a combined rate, both nationwide and split by the regions of prior mild and moderate ID.ResultsA total of 65 605 treatments were identified: 26 456 operations and 39 149 radioiodine treatments. In the first years of iodization (1998–2000; rate ratio 2000/1997), the combined treatment rate increased with 2.5% (95% confidence interval (CI): −1.8–7.1). Split by prior ID level, the increase was seen in the region of moderate ID, but a decrease was seen in the region of mild ID. After 2000, the combined rate decreased, and ended up being 11.1% (95% CI: 7.1–15.0) lower in 2007 than before iodization (rate ratio 2007/1997). The changes were primarily due to changes in the use of radioiodine therapy as the surgery rates remained almost constant.ConclusionsIodization seemed to be associated with a temporary increase in the utilization rate of surgery and radioiodine therapy in the region of prior moderate ID, probably as a result of treatment of iodine-induced hyperthyroidism, but the rates ended up being lower than before iodization.

Total Thyroidectomy for Benign Thyroid Disorders in an Endemic Region

2001 ◽  
Vol 25 (3) ◽  
pp. 307-310 ◽  
Author(s):  
Anjali Mishra ◽  
Amit Agarwal ◽  
Gaurav Agarwal ◽  
S.K. Mishra
Keyword(s):  
Total Thyroidectomy ◽  
Thyroid Disorders ◽  
Endemic Region ◽  
Benign Thyroid Disorders ◽  
Benign Thyroid

The role Of thyroid autotransplantation in patients with benign thyroid disorders

2019 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Adel Alawady ◽  
Alaal Khalil ◽  
salah abdelaal ◽  
Mohamed Alkilany ◽  
Hassan Ashour
Keyword(s):  
Thyroid Disorders ◽  
Benign Thyroid Disorders ◽  
Benign Thyroid
Sign in / Sign up

Export Citation Format

Share Document