scholarly journals Effects of Aspirin on Intra-Platelet Vascular Endothelial Growth Factor, Angiopoietin-1, and P-Selectin Levels in Hypertensive Patients

2006 ◽  
Vol 19 (9) ◽  
pp. 970-977 ◽  
Author(s):  
S NADAR ◽  
A BLANN ◽  
G LIP
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Vascular Endothelial ◽  
Hypertensive Patients ◽  
Endothelial Growth Factor ◽  
Angiopoietin 1

scholarly journals Role of Vascular Endothelial Growth Factor and Angiopoietin 1 in Renal Injury in Hemolytic Uremic Syndrome

2012 ◽  
Vol 36 (6) ◽  
pp. 516-523 ◽  
Author(s):  
Shinichiro Ohara ◽  
Yukihiko Kawasaki ◽  
Yusaku Abe ◽  
Masahiro Watanabe ◽  
Atsushi Ono ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Hemolytic Uremic Syndrome ◽  
Renal Injury ◽  
Vascular Endothelial ◽  
Uremic Syndrome ◽  
Endothelial Growth Factor ◽  
Angiopoietin 1

Gene Therapy by Adenovirus-Mediated Vascular Endothelial Growth Factor and Angiopoietin-1 Promotes Perfusion of Muscle Flaps

2002 ◽  
Vol 110 (1) ◽  
pp. 149-159 ◽  
Author(s):  
Przemyslaw Lubiatowski ◽  
Raffi Gurunluoglu ◽  
Corey K. Goldman ◽  
Blaazenka Skugor ◽  
Kevin Carnevale ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Vascular Endothelial ◽  
Muscle Flaps ◽  
Endothelial Growth Factor ◽  
Angiopoietin 1

scholarly journals Clinical Significance of Serum Levels of Vascular Endothelial Growth Factor, Angiopoietin-1, and Angiopoietin-2 in Patients with Rheumatoid Arthritis

2010 ◽  
Vol 37 (6) ◽  
pp. 1121-1128 ◽  
Author(s):  
DAITARO KUROSAKA ◽  
KENICHIRO HIRAI ◽  
MAKIKO NISHIOKA ◽  
YUKIO MIYAMOTO ◽  
KEN YOSHIDA ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Serum Levels ◽  
Vascular Endothelial ◽  
Angiopoietin 2 ◽  
Serum Crp ◽  
Endothelial Growth Factor ◽  
Vegf Level ◽  
Angiopoietin 1

Objective.To evaluate the clinical significance of serum levels of vascular endothelial growth factor (VEGF), angiopoietin-1 (Ang-1), and angiopoietin-2 (Ang-2) in patients with rheumatoid arthritis (RA).Methods.The subjects were 70 patients with RA. Serum VEGF, Ang-1, and Ang-2 levels were determined by ELISA. As indices of disease activity, serum levels of C-reactive protein (CRP) and matrix metalloprotease (MMP)-3 were examined, and the 28-joint count Disease Activity Score (DAS28)-CRP was calculated. Power Doppler ultrasonography was performed in the bilateral wrists, elbows, shoulders, knees and ankles. The synovial blood flow signals were scored using a 3-grade scale (0–2), and the total of the scores in the 10 joints was regarded as the total signal score (TSS).Results.Serum VEGF level showed significant correlations with serum CRP and MMP-3 levels, DAS28-CRP, and TSS. Serum Ang-1 level showed significant correlations with serum MMP-3 level and DAS28-CRP. Serum Ang-2 level showed significant correlations with serum CRP level and TSS.Conclusion.The serum VEGF level is important as an index of the activity of RA based on angiogenesis and a prognostic factor regarding joint destruction. Serum Ang-1 level may be useful as an index of sustained arthritis based on the maintenance of newly formed vessels. Serum Ang-2 level may reflect a state of marked angiogenesis.

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