scholarly journals Impact of transcendental meditation on ambulatory blood pressure in African-American adolescents

2004 ◽  
Vol 17 (4) ◽  
pp. 366-369 ◽  
Author(s):  
V Barnes
Keyword(s):  
Blood Pressure ◽  
African American ◽  
Ambulatory Blood Pressure ◽  
Transcendental Meditation ◽  
African American Adolescents

A Controlled Study of the Effects of the Transcendental Meditation® Program on Cardiovascular Reactivity and Ambulatory Blood Pressure

1997 ◽  
Vol 89 (1-2) ◽  
pp. 15-28 ◽  
Author(s):  
Stig R. Wenneberg ◽  
Robert H. Schneider ◽  
Kenneth G. Walton ◽  
Christopher R.K. Maclean ◽  
Debra K. Levitsky ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Reactivity ◽  
Ambulatory Blood Pressure ◽  
Transcendental Meditation ◽  
Controlled Study

scholarly journals Impact of Stress Reduction Interventions on Hostility and Ambulatory Systolic Blood Pressure in African American Adolescents

2010 ◽  
Vol 37 (2) ◽  
pp. 210-233 ◽  
Author(s):  
Lynda Brown Wright ◽  
Mathew J. Gregoski ◽  
Martha S. Tingen ◽  
Vernon A. Barnes ◽  
Frank A. Treiber
Keyword(s):  
Blood Pressure ◽  
African American ◽  
Systolic Blood Pressure ◽  
Stress Reduction ◽  
African American Adolescents

Abstract P181: Cardiac Structure is Associated with Obesity and Blood Pressure But Not Inflammation

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Robert A Palermo ◽  
Samuel S Gidding ◽  
Stehpanie S DeLoach ◽  
Scott W Keith ◽  
Bonita Falkner
Keyword(s):  
Blood Pressure ◽  
African American ◽  
Left Ventricular Mass Index ◽  
African American Adolescents ◽  
Female Gender ◽  
Left Ventricular ◽  
P Value ◽  
Cardiac Structure ◽  
Z Score ◽  
Pai 1

Purpose: The aim of this study was to identify risk factors associated with cardiac structure in a cohort of African American adolescents oversampled for obesity and high blood pressure (BP). Additional associations of cardiac structure with a pro-inflammatory adipokine profile (low adiponectin, elevated IL6, PAI-1 and CRP) were sought. Methods: A cross-sectional study was conducted using a two-by-two factorial design with four groups of African American adolescents based on BP (prehypertension or stage 1 hypertension=high BP) and body mass index (BMI > 95% =obese) designation. Measurements included: echocardiogram, anthropomorphics, BP (on 3 separate occasions), high sensitivity CRP and plasma adipokines (adiponectin, IL6, PAI-1). Standardized echocardiogram measurements were used to obtain left ventricular mass index (LVMI, g/m 2.7 ) and left atrial diameter index (LADI, mm/m 2 ). Ordinary least-squares regression with model selection by Mallow's Cp was used to determine if pro-inflammatory adipokine profile predicted LV mass and LA diameter in models including age, gender, BMI z-score, and systolic BP. Results: Data on 251 African American adolescents, ages 13-19, were analyzed. BMI-z score was strongly associated with a pro-inflammatory adipokine profile whereas high BP was not. Variation in LADI was significantly associated with BMI (β=0.12, p<0.01) and female gender (β=0.08, p=0.04). LVMI variation was significantly associated with BMI (β=3.53, p<0.01), age (β=0.71, p<0.01), female gender (β=-4.32, p<0.01), and systolic BP (β=0.10, p=0.03). Though significant in univariate models, inflammatory markers were not significantly associated with LADI or LVMI after BMI adjustment. Conclusions: In African American adolescents, BMI is an important determinant of LADI and LVMI. Obesity is associated with a pro-inflammatory adipokine profile but LADI and LVMI are not. Table. Regression modeling results after variable selection by Mallow C p : Left Atrium Diameter Index and Left Ventricular Mass Index (N = 251) LADI LVMI Estimate (95% CL) p-value Estimate (95% CL) p-value Age (yr) 0.00063 (-0.021, 0.023) 0.955 0.71 ( 0.18, 1.24) 0.009 Gender (F) 0.08 ( 0.01, 0.16) 0.036 −4.32 (-6.13,-2.51) <.001 BMI z-score 0.12 ( 0.08, 0.16) <.001 3.53 ( 2.66, 4.40) <.001 Systolic BP 0.0019 (-0.0017, 0.0055) 0.306 0.0952 ( 0.0085, 0.1819) 0.032

scholarly journals Impact of Transcendental Meditation on Left Ventricular Mass in African American Adolescents

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Vernon A. Barnes ◽  
Gaston K. Kapuku ◽  
Frank A. Treiber
Keyword(s):  
African American ◽  
Left Ventricular Mass ◽  
Ventricular Remodeling ◽  
Transcendental Meditation ◽  
African American Adolescents ◽  
Left Ventricular ◽  
Ventricular Mass ◽  
Cardiovascular Morbidity And Mortality ◽  
Before And After

Background. An early sign of ventricular remodeling is increased left ventricular mass (LVM) which over time may lead to left ventricular hypertrophy, the strongest predictor of cardiovascular morbidity and mortality, other than advancing age.Methods. 62 (30 TM; 32 CTL) African American adolescents (age16.2±1.3years) with high normal systolic BP were randomly assigned to either 4-month Transcendental Meditation (TM) or health education control groups. The echocardiographic-derived measure of LVM index (LVMI = LVM/ht2.7) was measured before and after the 4-month TM study and at 4-month followup. 2D-guided M-mode echocardiography using a Hewlett Packard 5500 echosonograph was used to determine LVMI.Results. The TM group exhibited a greater decrease in LVMI at 4-month followup compared to the CTL group (−2.6 versus +0.3 gm/ht2.7,P<0.04). The TM group exhibited a lesser increase in BMI at 4-month follow-up compared to the CTL group (0.2±1.6versus1.1±1.4,P<0.03).Conclusion. These findings indicate that among a group of prehypertensive African American adolescents, 4 months of TM compared to heath education resulted in a significant decrease in LVMI, and these changes were maintained at 4-month follow-up.

scholarly journals Differential Impact of Stress Reduction Programs upon Ambulatory Blood Pressure among African American Adolescents: Influences of Endothelin-1 Gene and Chronic Stress Exposure

2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
Mathew J. Gregoski ◽  
Vernon A. Barnes ◽  
Martha S. Tingen ◽  
Yanbin Dong ◽  
Haidong Zhu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
African American ◽  
Chronic Stress ◽  
Behavioral Interventions ◽  
High Stress ◽  
African American Adolescents ◽  
Skills Training ◽  
Individual Variability ◽  
Stress Exposure ◽  
Endothelin 1

Stress-activated gene × environment interactions may contribute to individual variability in blood pressure reductions from behavioral interventions. We investigated effects of endothelin-1 (ET-1) LYS198ASN SNP and discriminatory stress exposure upon impact of 12-week behavioral interventions upon ambulatory BP (ABP) among 162 prehypertensive African American adolescents. Following genotyping, completion of questionnaire battery, and 24-hour ABP monitoring, participants were randomized to health education control (HEC), life skills training (LST), or breathing awareness meditation (BAM). Postintervention ABP was obtained. Significant three-way interactions on ABP changes indicated that among ET-1 SNP carriers, the only group to show reductions was BAM from low chronic stress environments. Among ET-1 SNP noncarriers, under low chronic stress exposure, all approaches worked, especially BAM. Among high stress exposure noncarriers, only BAM resulted in reductions. If these preliminary findings are replicated via ancillary analyses of archival databases and then via efficacy trials, selection of behavioral prescriptions for prehypertensives will be edging closer to being guided by individual's underlying genetic and environmental factors incorporating the healthcare model of personalized preventive medicine.

Abstract P209: Net Worth, Debt Stress, And Ambulatory Blood Pressure In African American Women

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Telisa Spikes ◽  
Raphiel Murden ◽  
Izraelle McKinnon ◽  
Miriam Van Dyke ◽  
Samantha Bromfield ◽  
...  
Keyword(s):  
Blood Pressure ◽  
African American ◽  
African American Women ◽  
Ambulatory Blood Pressure ◽  
Stress Index ◽  
Cvd Risk ◽  
Net Worth ◽  
American Women ◽  
Incidence And Mortality ◽  
Debt Stress

Title: Net Worth, Debt Stress, and Ambulatory Blood Pressure in African American Women Author Names: Telisa Spikes, RN, PHD, Raphiel Murden, MS, Izraelle McKinnon, MPH, Miriam Van Dyke, PhD, Samantha Bromfield, PhD, Renee Moore, PhD, Bianca Booker, MA, Frederic Rahbari-Oskoui MD, Arshed Quyyumi, MD, Viola Vaccarino, MD, PhD, Tené T. Lewis, PhD Background: Low socioeconomic status (SES) is an established predictor of higher cardiovascular disease (CVD) incidence and mortality. Research suggests that neither higher education nor income have been consistently associated with lower CVD risk or outcomes in African Americans (AAs). Net worth and debt stress are two underexamined indices of SES that may be more important for CVD risk, especially in AAs, due to attenuated returns of traditional indicators of SES on health, and the high rates of debt in this group. Objective: To examine the associations of net worth and debt stress, independent of education and income, with ambulatory blood pressure (ABP) in AA women. Methods: Participants were AA women (n=422), mean age 37±4.2 years from various sociodemographic backgrounds recruited from a large metropolitan southeastern region. Net worth was measured using a single item (“Suppose you and others in your household were to sell all of your major possessions including your home, turn all of your investments and other assets into cash, and pay off all of your debts. Would you have something left over, break even, or be in debt?”) with three response categories, left over , break-even , and debt . Debt stress was measured using the four-item Debt Stress Index (e.g. “Overall, how often do you worry about the total amount you and your spouse/partner owe in overall debt?”). ABP was assessed over 48 hours. Multiple linear regression was used to evaluate associations between SES indicators and continuous ABP outcomes adjusting for age, education, income, BMI, BP meds, and depressive symptoms. Results: Overall, 48% of the cohort was categorized as having a positive (“left over”) net worth, while 30% and 22% were categorized as having a neutral (“break-even”), and negative (“debt”) net worth, respectively. Compared to the positive net worth group, negative net worth was associated with higher daytime (ß=5.2; CI: 2.44-8.05 ) and nighttime systolic blood pressure (SBP) (ß=5.3; CI: 2.59-8.06 ) in unadjusted analyses. Findings remained significant for both daytime (ß=4.3; CI:1.38-7.24 ) and nighttime (ß=4.1; CI:1.26-6.90 ) SBP in fully adjusted models. There were no significant unadjusted or fully-adjusted associations between debt stress and daytime, or nighttime SBP. Discussion: Negative net worth was associated with a 4.3 mm Hg higher daytime, and 4.1 mm Hg nighttime SBP independent of education and income. Future research is needed to determine the prospective impact of net worth on long-term CVD risk in AA women.

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