scholarly journals Identification of Coiled-Coil Domain–Containing Protein 180 and Leucine-Rich Repeat–Containing Protein 4 as Potential Immunohistochemical Markers for Liposarcoma Based on Proteomic Analysis Using Formalin-Fixed, Paraffin-Embedded Tissue

2019 ◽  
Vol 189 (5) ◽  
pp. 1015-1028 ◽  
Author(s):  
Tomoyuki Aoyama ◽  
Akira Takasawa ◽  
Kumi Takasawa ◽  
Yusuke Ono ◽  
Makoto Emori ◽  
...  
Keyword(s):  
Proteomic Analysis ◽  
Coiled Coil ◽  
Leucine Rich Repeat ◽  
Immunohistochemical Markers ◽  
Coiled Coil Domain ◽  
Formalin Fixed Paraffin ◽  
Formalin Fixed Paraffin Embedded ◽  
Formalin Fixed

Impact of routinely employed procedures for tissue processing on the proteomic analysis of formalin-fixed paraffin-embedded tissue

2014 ◽  
Vol 8 (9-10) ◽  
pp. 796-804 ◽  
Author(s):  
Peter Bronsert ◽  
Juliane Weißer ◽  
Martin L. Biniossek ◽  
Markus Kuehs ◽  
Bettina Mayer ◽  
...  
Keyword(s):  
Proteomic Analysis ◽  
Tissue Processing ◽  
Formalin Fixed Paraffin ◽  
Formalin Fixed Paraffin Embedded ◽  
Formalin Fixed

scholarly journals Quantitative Proteomic Analysis of Formalin Fixed Paraffin Embedded Oral HPV Lesions from HIV Patients

2008 ◽  
Vol 1 (1) ◽  
pp. 40-45 ◽  
Author(s):  
Mohit Raja Jain ◽  
Tong Liu ◽  
Jun Hu ◽  
Marlene Darfler ◽  
Valerie Fitzhugh ◽  
...  
Keyword(s):  
Proteomic Analysis ◽  
Hiv Patients ◽  
Quantitative Proteomic Analysis ◽  
Formalin Fixed Paraffin ◽  
Formalin Fixed Paraffin Embedded ◽  
Oral Hpv ◽  
Formalin Fixed

scholarly journals Immunohistochemical Staining Patterns of Canine Meningiomas and Correlation with Published Immunophenotypes

2002 ◽  
Vol 39 (3) ◽  
pp. 311-321 ◽  
Author(s):  
K. F. Barnhart ◽  
J. Wojcieszyn ◽  
R. W. Storts
Keyword(s):  
Immunohistochemical Staining ◽  
Neuron Specific Enolase ◽  
Positive Staining ◽  
Neoplastic Cells ◽  
Vimentin Expression ◽  
Immunohistochemical Markers ◽  
Formalin Fixed Paraffin ◽  
Tumor Group ◽  
Formalin Fixed Paraffin Embedded ◽  
Formalin Fixed

This study examined immunohistochemical staining patterns for several meningioma variants involving either the brain or spinal cord of dogs. Formalin-fixed, paraffin-embedded tissue from 15 tumors was obtained. The selected tumor group included seven meningothelial, three transitional, two malignant (anaplastic), one myxoid, one papillary, and one osteomatous meningiomas. Tumors were evaluated for reactivity to the following six immunohistochemical markers: vimentin, pancytokeratin, glial fibrillary acidic protein (GFAP), S100, neuron-specific enolase (NSE), and synaptophysin. Vimentin expression was detected in all meningiomas, and 14 of 15 tumors demonstrated intense vimentin staining in more than 50% of the neoplastic cells. Pancytokeratin expression was present in 11 of 15 neoplasms; however, positive staining frequently was focal and often involved a small percentage of the neoplastic cells. GFAP expression was detected in a single, anaplastic meningioma. Although expression of NSE and S100 was detected in 12 of 25 meningiomas, the intensity of the staining and the percentage of positive neoplastic cells was highly variable. Synaptophysin was uniformly negative. These results will help to establish immunohistochemical profiles for meningiomas that will improve our ability to correctly differentiate these neoplasms of meningeal origin from central nervous system tumors originating from other sites.

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