scholarly journals Establishment and Characterization of Orthotopic Mouse Models for Human Uveal Melanoma Hepatic Colonization

2016 ◽  
Vol 186 (1) ◽  
pp. 43-56 ◽  
Author(s):  
Shinji Ozaki ◽  
Raja Vuyyuru ◽  
Ken Kageyama ◽  
Mizue Terai ◽  
Masahiro Ohara ◽  
...  
Keyword(s):  
Mouse Models ◽  
Uveal Melanoma

Abstract 3228: Establishment and characterization of orthotopic mouse models for human uveal melanoma hepatic metastases

2015 ◽  
Author(s):  
Shinji Ozaki ◽  
Mizue Terai ◽  
Ken Kageyama ◽  
Hanyin Cheng ◽  
Masahiro Ohara ◽  
...  
Keyword(s):  
Mouse Models ◽  
Uveal Melanoma ◽  
Hepatic Metastases

scholarly journals Characterization of tumor‐associated macrophages in prostate cancer transgenic mouse models

The Prostate ◽  
2021 ◽  
Author(s):  
Amber E. Groot ◽  
Kayla V. Myers ◽  
Timothy E. G. Krueger ◽  
Ashley L. Kiemen ◽  
Natalia H. Nagy ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Transgenic Mouse ◽  
Mouse Models ◽  
Transgenic Mouse Models ◽  
Tumor Associated Macrophages

scholarly journals Characterization of the HollandPTC proton therapy beamline dedicated to uveal melanoma treatment and an interinstitutional comparison

2021 ◽  
Author(s):  
Emmanuelle Fleury ◽  
Petra Trnková ◽  
Kees Spruijt ◽  
Joël Herault ◽  
Franciska Lebbink ◽  
...  
Keyword(s):  
Uveal Melanoma ◽  
Proton Therapy ◽  
Melanoma Treatment

scholarly journals Characterization of Mouse Models of Early Pancreatic Lesions Induced by Alcohol and Chronic Pancreatitis

Pancreas ◽  
2015 ◽  
Vol 44 (6) ◽  
pp. 882-887 ◽  
Author(s):  
Shiping Xu ◽  
Chintan Chheda ◽  
Yassine Ouhaddi ◽  
Hajar Benhaddou ◽  
Mouloud Bourhim ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Mouse Models

scholarly journals Characterization of common SMPD1 mutations causing types A and B Niemann-Pick disease and generation of mutation-specific mouse models

2008 ◽  
Vol 95 (3) ◽  
pp. 152-162 ◽  
Author(s):  
Iwan Jones ◽  
Xingxuan He ◽  
Fourogh Katouzian ◽  
Peter I. Darroch ◽  
Edward H. Schuchman
Keyword(s):  
Mouse Models ◽  
Niemann Pick Disease ◽  
Niemann Pick ◽  
Pick Disease

Characterization of the two inducible Cre recombinase-based mouse models NG2- CreERTM and PDGFRb-P2A-CreERT2 for pericyte labeling in the retina

2021 ◽  
Author(s):  
Daniela Mayr ◽  
Julia Preishuber-Pflügl ◽  
Andreas Koller ◽  
Susanne M. Brunner ◽  
Christian Runge ◽  
...  
Keyword(s):  
Mouse Models ◽  
Cre Recombinase

Establishment and characterization of cell lines and xenograft mouse models of canine systemic histiocytosis and disseminated histiocytic sarcoma.

2021 ◽  
Author(s):  
Miyuki Hirabayashi ◽  
James K. Chambers ◽  
Takuya E. Kishimoto ◽  
Nguyen V. Son ◽  
Yuichi Ishikawa ◽  
...  
Keyword(s):  
Mouse Models ◽  
Cell Lines ◽  
Histiocytic Sarcoma

scholarly journals Characterization of spatio-temporal epidural event-related potentials for mouse models of psychiatric disorders

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Xin Wang ◽  
António Pinto-Duarte ◽  
M. Margarita Behrens ◽  
Xianjin Zhou ◽  
Terrence J. Sejnowski
Keyword(s):  
Psychiatric Disorders ◽  
Mouse Models ◽  
Event Related Potentials ◽  
Related Potentials ◽  
Spatio Temporal

scholarly journals In vivo measurement of intrauterine pressure by telemetry: a new approach for studying parturition in mouse models

2010 ◽  
Vol 42 (2) ◽  
pp. 310-316 ◽  
Author(s):  
Stephanie L. Pierce ◽  
William Kutschke ◽  
Rafael Cabeza ◽  
Sarah K. England
Keyword(s):  
Mouse Models ◽  
Accurate Method ◽  
Isometric Tension ◽  
Mouse Uterus ◽  
New Approach ◽  
In Vivo Measurement ◽  
Intrauterine Pressure

Transgenic and knockout mouse models have proven useful in the study of genes necessary for parturition—including genes that affect the timing and/or progression of labor contractions. However, taking full advantage of these models will require a detailed characterization of the contractile patterns in the mouse uterus. Currently the best methodology for this has been measurement of isometric tension in isolated muscle strips in vitro. However, this methodology does not provide a real-time measure of changes in uterine pressure over the course of pregnancy. Recent advances have opened the possibility of using radiotelemetric devices to more accurately and comprehensively study intrauterine pressure in vivo. We tested the effectiveness of this technology in the mouse, in both wild-type (WT) mice and a mouse model of defective parturition (SK3 channel-overexpressing mice), after surgical implant of telemetry transmitters into the uterine horn. Continuous recordings from day 18 of pregnancy through delivery revealed that WT mice typically deliver during the 12-h dark cycle after 19.5 days postcoitum. In these mice, intrauterine pressure gradually increases during this cycle, to threefold greater than that measured during the 12-h cycle before delivery. SK3-overexpressing mice, by contrast, exhibited lower intrauterine pressure over the same period. These results are consistent with the outcome of previous in vitro studies, and they indicate that telemetry is an accurate method for measuring uterine contraction, and hence parturition, in mice. The use of this technology will lead to important novel insights into changes in intrauterine pressure during the course of pregnancy.

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