scholarly journals Characterization of the Intrarenal Renin-Angiotensin System in Experimental Alport Syndrome

2015 ◽  
Vol 185 (5) ◽  
pp. 1423-1435 ◽  
Author(s):  
Eun Hui Bae ◽  
Ana Konvalinka ◽  
Fei Fang ◽  
Xiaohua Zhou ◽  
Vanessa Williams ◽  
...  
Keyword(s):  
Alport Syndrome ◽  
Renin Angiotensin System ◽  
Angiotensin System ◽  
Renin Angiotensin

390 Characterization of the Renin-Angiotensin System Regulation in Cavernosal Tissue of Aged Rats

2017 ◽  
Vol 14 (1) ◽  
pp. S115-S116
Author(s):  
M.E. Bragina ◽  
R.A. Fraga-Silva ◽  
F.P. Costa-Fraga ◽  
N. Stergiopulos
Keyword(s):  
Renin Angiotensin System ◽  
Aged Rats ◽  
Angiotensin System ◽  
Renin Angiotensin

scholarly journals Characterization of a Local Renin-Angiotensin System in Rat Gingival Tissue

2009 ◽  
Vol 80 (1) ◽  
pp. 130-139 ◽  
Author(s):  
C.F. Santos ◽  
A.E. Akashi ◽  
T.J. Dionísio ◽  
C.R. Sipert ◽  
D.N. Didier ◽  
...  
Keyword(s):  
Renin Angiotensin System ◽  
Gingival Tissue ◽  
Angiotensin System ◽  
Renin Angiotensin

Angiotensin-dependent renal mechanisms in two-kidney, one-clip renal vascular hypertension

1983 ◽  
Vol 245 (2) ◽  
pp. F131-F141 ◽  
Author(s):  
D. W. Ploth
Keyword(s):  
Blood Pressure ◽  
Renin Angiotensin System ◽  
Systemic Blood Pressure ◽  
Systemic Circulation ◽  
Systemic Hemodynamic ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
Renal Vascular ◽  
Pharmacologic Agents

Our understanding of the physiology of the renin-angiotensin system has advanced remarkably in the last decade as a result of the development of several pharmacologic agents that effectively block components of this humoral cascade. The use of these antagonists has also advanced our understanding of the contribution of the renin-angiotensin system to the development and maintenance of two-kidney, one-clip renal vascular hypertension. These antagonists have contributed greatly to the characterization of the systemic hemodynamic changes that occur in this model and, particularly, to the delineation of the behavior of the nonclipped kidney, a previously normal kidney that is subjected acutely to an environment of elevated systemic blood pressure and the input of a variety of other extrinsic influences. This kidney not only allows the blood pressure to increase and persist at elevated levels but appears to actively participate in the development and propagation of the hypertension. Although a variety of mechanisms impinge on the function of the nonclipped kidney in this model, the goal of this review is to analyze the behavior of this kidney and how its functional state is perturbed, primarily by the influence of angiotensin, which is believed to be delivered to it by the systemic circulation.

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