scholarly journals Role of the Nuclear Receptor Coactivator AIB1/SRC-3 in Angiogenesis and Wound Healing

2012 ◽  
Vol 180 (4) ◽  
pp. 1474-1484 ◽  
Author(s):  
Maram Al-Otaiby ◽  
Elena Tassi ◽  
Marcel O. Schmidt ◽  
Chris D. Chien ◽  
Tabari Baker ◽  
...  
Keyword(s):  
Wound Healing ◽  
Nuclear Receptor ◽  
Nuclear Receptor Coactivator

scholarly journals Role of Nuclear Receptor Coactivator 3 (Ncoa3) in Pluripotency Maintenance

2012 ◽  
Vol 287 (45) ◽  
pp. 38295-38304 ◽  
Author(s):  
Zhaoting Wu ◽  
Meng Yang ◽  
Hongjie Liu ◽  
Hongchao Guo ◽  
Yuan Wang ◽  
...  
Keyword(s):  
Nuclear Receptor ◽  
Nuclear Receptor Coactivator ◽  
Pluripotency Maintenance

scholarly journals Role of the Nuclear Receptor Coactivator AIB1-Δ4 Splice Variant in the Control of Gene Transcription

2011 ◽  
Vol 286 (30) ◽  
pp. 26813-26827 ◽  
Author(s):  
Christopher D. Chien ◽  
Alexander Kirilyuk ◽  
Jordan V. Li ◽  
Wentao Zhang ◽  
Tyler Lahusen ◽  
...  
Keyword(s):  
Nuclear Receptor ◽  
Gene Transcription ◽  
Splice Variant ◽  
Nuclear Receptor Coactivator

Experience of negative pressure wound therapy over sternal wound healing: A retrospective review

WCET Journal ◽  
2019 ◽  
Vol 39 (2) ◽  
pp. 9-18
Author(s):  
Wai Sze Ho ◽  
Wai Kuen Lee ◽  
Ka Kay Chan ◽  
Choi Ching Fong
Keyword(s):  
Wound Healing ◽  
Negative Pressure ◽  
Negative Pressure Wound Therapy ◽  
Assessment Tool ◽  
Wound Care ◽  
Wound Therapy ◽  
Treatment Pathways ◽  
Wound Assessment ◽  
One Year

Objectives The aim of this study was to retrospectively review the effectiveness of negative pressure wound therapy (NPWT) in sternal wound healing with the use of the validated Bates-Jensen Wound Assessment Tool (BWAT), and explore the role of NPWT over sternal wounds and future treatment pathways. Methods Data was gathered from patients' medical records and the institution's database clinical management system. Seventeen subjects, who had undergone cardiothoracic surgeries and subsequently consulted the wound care team in one year were reviewed. Fourteen of them were included in the analysis. Healing improvement of each sternal wound under continuous NPWT and continuous conventional dressings was studied. In total, 23 continuous NPWT and 13 conventional dressing episodes were analysed with the BWAT. Results Among conventional dressing episodes, sternal wound improvement was 2.5–3% over 10 days to 3.5 weeks, whereas 4–5% sternal healing was achieved in 5 days to 2 weeks with sternal wire presence. Better healing at 11% in 1 week by conventional dressing was attained after sternal wire removal. In NPWT episodes, 8–29%, 13–24%, and 15–46% of healing was observed in 2 weeks, 3.5 to 5 weeks and 6 to 7 weeks, respectively. Only 39% wound healing was acquired at the 13th week of NPWT in one subject. With sternal wire present, 6%–29% wound healing progress was achieved by NPWT in 1–4 weeks, and 16–23% wound improvement in 2 to 4.5 weeks by NWPT after further surgical debridement. After sternal wire removal, 6–34% sternal wound healing occurred by continuous NPWT for 1–2 weeks, and maximum healing at 46% after 2.5 weeks of NPWT were observed. Conclusions Better wound healing was achieved in the NPWT group in comparison to conventional dressings alone. However, suboptimal sternal wound healing by NPWT alone was observed. Removal of sternal wire may improve the effectiveness of NPWT. Successful tertiary closure after NPWT among subjects supports the important bridging role of NPWT in sternal wound healing. Factors causing stagnant sternal wound healing by NPWT alone are discussed.

The role of angiopoetic factors in wound healing among patients with diabetes treated with negative-pressure wound therapy

Leczenie Ran ◽  
2015 ◽  
Vol 11 (4) ◽  
pp. 171-178
Author(s):  
Beata Mrozikiewicz-Rakowska ◽  
Joanna Kania ◽  
Ewelina Bucior ◽  
Adriana Nowak ◽  
Tomasz Grzela ◽  
...  
Keyword(s):  
Wound Healing ◽  
Negative Pressure ◽  
Negative Pressure Wound Therapy ◽  
Wound Therapy ◽  
Patients With Diabetes
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