A point prevalence survey of health care–associated infections in pediatric populations in major Canadian acute care hospitals

2007 ◽  
Vol 35 (3) ◽  
pp. 157-162 ◽  
Author(s):  
Denise Gravel ◽  
Anne Matlow ◽  
Marianna Ofner-Agostini ◽  
Mark Loeb ◽  
Lynn Johnston ◽  
...  
Antibiotics ◽  
2020 ◽  
Vol 9 (6) ◽  
pp. 288
Author(s):  
Seven Johannes Sam Aghdassi ◽  
Petra Gastmeier ◽  
Michael Behnke ◽  
Sonja Hansen ◽  
Tobias Siegfried Kramer

Despite limited indications, redundant anaerobic antimicrobial prescriptions (RAAPs) are frequent. The objective of this study was to assess the prevalence and characteristics of RAAPs in German acute care hospitals. In a retrospective data analysis, antimicrobial prescriptions from a point prevalence survey on antimicrobial use in German acute care hospitals in 2016 were analyzed and RAAPs were identified. RAAPs were defined as a patient simultaneously receiving any of the following combinations: Penicillin/beta-lactamase inhibitor (PenBLI) plus clindamycin; PenBLI plus metronidazole; PenBLI plus moxifloxacin; PenBLI plus carbapenem; carbapenem plus clindamycin; carbapenem plus metronidazole; carbapenem plus moxifloxacin; clindamycin plus metronidazole; clindamycin plus moxifloxacin; and metronidazole plus moxifloxacin. Data from 64,412 patients in 218 hospitals were included. Overall, 4486 patients (7%) received two or more antimicrobials. In total, 441 RAAP combinations were identified. PenBLI plus metronidazole was the most common anaerobic combination (N = 166, 38%). The majority of RAAPs were for the treatment of community-acquired (N = 258, 59%) infections. Lower respiratory tract infections (N = 77; 20%) and skin/soft tissue infections (N = 76; 20%) were the most frequently recorded types of infections. RAAPs are common in German hospitals. Reducing redundant antimicrobial coverage should be a key component of future antimicrobial stewardship activities.


2019 ◽  
Vol 191 (36) ◽  
pp. E981-E988 ◽  
Author(s):  
Robyn Mitchell ◽  
Geoffrey Taylor ◽  
Wallis Rudnick ◽  
Stephanie Alexandre ◽  
Kathryn Bush ◽  
...  

2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S511-S511
Author(s):  
Christopher Evans ◽  
Raphaelle Beard ◽  
Zina Gugkaeva ◽  
Brooke Stayer ◽  
Candice Simpson ◽  
...  

2018 ◽  
Vol 23 (32) ◽  
Author(s):  
Jan Walter ◽  
Sebastian Haller ◽  
Chantal Quinten ◽  
Tommi Kärki ◽  
Benedikt Zacher ◽  
...  

An aim of the ECDC point prevalence survey (PPS) in European Union/European Economic Area acute care hospitals was to acquire standardised healthcare-associated infections (HAI) data. We analysed one of the most common HAIs in the ECDC PPS, healthcare-associated pneumonia (HAP). Standardised HAI case definitions were provided and countries were advised to recruit nationally representative subsets of hospitals. We calculated 95% confidence intervals (CIs) around prevalence estimates and adjusted for clustering at hospital level. Of 231,459 patients in the survey, 2,902 (1.3%; 95% CI: 1.2–1.3) fulfilled the case definition for a HAP. HAPs were most frequent in intensive care units (8.1%; 95% CI: 7.4–8.9) and among patients intubated on the day of the survey (15%; 95% CI: 14–17; n = 737 with HAP). The most frequently reported microorganism was Pseudomonas aeruginosa (17% of 1,403 isolates), followed by Staphylococcus aureus (12%) and Klebsiella spp. (12%). Antimicrobial resistance was common among isolated microorganisms. The most frequently prescribed antimicrobial group was penicillins, including combinations with beta-lactamase inhibitors. HAPs occur regularly among intubated and non-intubated patients, with marked differences between medical specialities. HAPs remain a priority for preventive interventions, including surveillance. Our data provide a reference for future prevalence of HAPs at various settings.


2014 ◽  
Vol 370 (13) ◽  
pp. 1198-1208 ◽  
Author(s):  
Shelley S. Magill ◽  
Jonathan R. Edwards ◽  
Wendy Bamberg ◽  
Zintars G. Beldavs ◽  
Ghinwa Dumyati ◽  
...  

2019 ◽  
Vol 24 (46) ◽  
Author(s):  
Seven Johannes Sam Aghdassi ◽  
Frank Schwab ◽  
Sonja Hansen ◽  
Luis Alberto Peña Diaz ◽  
Michael Behnke ◽  
...  

Background Robust data on the quality of antimicrobial prescriptions in German acute care hospitals are scarce. To establish and implement antimicrobial stewardship (AMS) measures and to increase prudent antimicrobial use (AMU), the identification of appropriate process and quality indicators is pertinent. Aim Our main objective was to identify parameters associated with adequate AMU and inadequate AMU by analysing point prevalence data. Our secondary goal was to describe the current state of AMS implementation in Germany. Methods A national point prevalence survey for healthcare-associated infections and AMU was conducted in German hospitals in 2016. Data on structure and process parameters were also collected. Recorded antimicrobial prescriptions were divided into adequate, inadequate and undefinable AMU. A multivariable linear regression analysis was performed to examine the correlation of selected structure and process parameters with the adequacy of recorded antimicrobials. Results Data from 218 acute care hospitals, 64,412 patients and 22,086 administered antimicrobials were included. Multivariable linear regression analysis revealed that documentation of a reason for AMU in the patient notes increased the likelihood of adequate AMU and decreased the likelihood of inadequate AMU significantly (p < 0.001), while tertiary care hospital type had the opposite effect (p < 0.001). Conclusion Through associating structural and process parameters with adequacy of AMU, we identified parameters that increased the odds of prudent AMU. Documentation was a key element for improving AMU. Revealed deficits regarding the implementation of AMS in German hospitals concerning dedicated staff for AMS activities and establishment of regular AMU training and AMU audits should be tackled.


2012 ◽  
Vol 40 (6) ◽  
pp. 491-496 ◽  
Author(s):  
Katie Rutledge-Taylor ◽  
Anne Matlow ◽  
Denise Gravel ◽  
Joanne Embree ◽  
Nicole Le Saux ◽  
...  

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