scholarly journals Immunoconjugates and long circulating systems: Origins, current state of the art and future directions

2013 ◽  
Vol 65 (1) ◽  
pp. 24-35 ◽  
Author(s):  
Alexander Koshkaryev ◽  
Rupa Sawant ◽  
Madhura Deshpande ◽  
Vladimir Torchilin
Sensors ◽  
2020 ◽  
Vol 20 (9) ◽  
pp. 2554 ◽  
Author(s):  
Mohammad Reza Zamani Kouhpanji ◽  
Bethanie J. H. Stadler

The remarkable multimodal functionalities of magnetic nanoparticles, conferred by their size and morphology, are very important in resolving challenges slowing the progression of nanobiotechnology. The rapid and revolutionary expansion of magnetic nanoparticles in nanobiotechnology, especially in nanomedicine and therapeutics, demands an overview of the current state of the art for synthesizing and characterizing magnetic nanoparticles. In this review, we explain the synthesis routes for tailoring the size, morphology, composition, and magnetic properties of the magnetic nanoparticles. The pros and cons of the most popularly used characterization techniques for determining the aforementioned parameters, with particular focus on nanomedicine and biosensing applications, are discussed. Moreover, we provide numerous biomedical applications and highlight their challenges and requirements that must be met using the magnetic nanoparticles to achieve the most effective outcomes. Finally, we conclude this review by providing an insight towards resolving the persisting challenges and the future directions. This review should be an excellent source of information for beginners in this field who are looking for a groundbreaking start but they have been overwhelmed by the volume of literature.


2013 ◽  
Vol 5 (6) ◽  
pp. 525-538 ◽  
Author(s):  
Andrew Shawyer ◽  
Mark D Goodwin ◽  
Robert N Gibson

Author(s):  
Mica R. Endsley ◽  
Gary Klein ◽  
David D. Woods ◽  
Philip J. Smith ◽  
Stephen J. Selcon

Cognitive Engineering and Naturalistic Decision Making are presented as two related fields of endeavor that seek to understand how people process information and perform within complex systems and to develop ways of applying this knowledge within the design and training process This panel presents an overview of the current state of the art in this research domain and charts paths for needed developments in the field in the near future.


2008 ◽  
Vol 23 (3) ◽  
pp. 227-260 ◽  
Author(s):  
DANIEL BRYANT ◽  
PAUL KRAUSE

AbstractThis article surveys existing practical implementations of both defeasible and argumentation-based reasoning engines and associated literature. We aim to summarize the current state of the art in the research area, show that there are many similiarities and connections between the various implementations and also highlight the differences regarding evaluation goals and strategies. An important goal of this paper is to argue for the need for well-designed empirical evaluations, as well as formal complexity analysis, in order to justify the practical applicability of a reasoning engine. There are indeed many challenges to be faced in developing implementations of argumentation. Not least of these is the inherent computational complexity of the formal models. We cover some of the ways these challenges have been addressed, and provide pointers for future directions in realizing the goal of practical argumentation.


2020 ◽  
Author(s):  
Yu Hsuan Lee ◽  
Ravi Kumar ◽  
Jacob Benz ◽  
HaliAnne McGee-Hilbert ◽  
Geoffrey Hollinger ◽  
...  

Informatics ◽  
2020 ◽  
Vol 7 (4) ◽  
pp. 37
Author(s):  
Loraine Franke ◽  
Daniel Haehn

Modern scientific visualization is web-based and uses emerging technology such as WebGL (Web Graphics Library) and WebGPU for three-dimensional computer graphics and WebXR for augmented and virtual reality devices. These technologies, paired with the accessibility of websites, potentially offer a user experience beyond traditional standalone visualization systems. We review the state-of-the-art of web-based scientific visualization and present an overview of existing methods categorized by application domain. As part of this analysis, we introduce the Scientific Visualization Future Readiness Score (SciVis FRS) to rank visualizations for a technology-driven disruptive tomorrow. We then summarize challenges, current state of the publication trend, future directions, and opportunities for this exciting research field.


2021 ◽  
Vol 10 (21) ◽  
pp. 5203
Author(s):  
Katherine Brain ◽  
Tracy L. Burrows ◽  
Laura Bruggink ◽  
Anneleen Malfliet ◽  
Chris Hayes ◽  
...  

Nutrition plays an important role in pain management. Healthy eating patterns are associated with reduced systemic inflammation, as well as lower risk and severity of chronic non-cancer pain and associated comorbidities. The role of nutrition in chronic non-cancer pain management is an emerging field with increasing interest from clinicians and patients. Evidence from a number of recent systematic reviews shows that optimising diet quality and incorporating foods containing anti-inflammatory nutrients such as fruits, vegetables, long chain and monounsaturated fats, antioxidants, and fibre leads to reduction in pain severity and interference. This review describes the current state of the art and highlights why nutrition is critical within a person-centred approach to pain management. Recommendations are made to guide clinicians and highlight areas for future research.


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